Rchr
J-GLOBAL ID：200901000465018672   Update date: Jan. 30, 2024

Uekita Takamasa

ウエキタ タカマサ | Uekita Takamasa
Affiliation and department：
National Defense Academy Department of Applied Chemistry, Genome Biology

About National Defense Academy Department of Applied Chemistry, Genome Biology


Job title： Associate Professor
Research field  (4)： Tumor biology ,  Experimental pathology ,  Pathobiochemistry ,  Cell biology
Research keywords  (10)： シグナル伝達 ,  浸潤・転移 ,  細胞生物学 ,  機能生物化学 ,  腫瘍学 ,  Metastasis ,  Invasion ,  Cancer ,  Cell Biology ,  Functional Biochemistry
Research theme for competitive and other funds  (11)：
  • 2021 - 2024 Basic research on the development of new therapeutic methods for cancer metastasis targeting the CDCP1 extracellular domain
  • 2020 - 2023 複合刺激応答型金属錯体に立脚した選択的抗がん剤の開発
  • 2015 - 2018 Basic research on cancer therapy development targeting anchorage independence
  • 2012 - 2015 Analysis of the mechanism of cancer progression that overcome the cellular senescence by activated Ras
  • 1998 - 2007 MT1-MMPの細胞内ドメインの機能解析
Show all
Papers (27)：
  • Masato Taoka, Kota Kamei, Akiko Kashima, Yuko Nobe, Takahiro Takekiyo, Takamasa Uekita, Tohru Ichimura. An ionic liquid-assisted sample preparation method for sensitive integral-membrane proteome analysis. Analytical biochemistry. 2023. 683. 115349-115349
  • Takafumi Tozawa, Kohichi Matsunaga, Tetsuro Izumi, Naotake Shigehisa, Takamasa Uekita, Masato Taoka, Tohru Ichimura. Ubiquitination-coupled liquid phase separation regulates the accumulation of the TRIM family of ubiquitin ligases into cytoplasmic bodies. PloS one. 2022. 17. 8. e0272700
  • Masato Taoka, Koji Horita, Takahiro Takekiyo, Takamasa Uekita, Yukihiro Yoshimura, Tohru Ichimura. An Ionic Liquid-Based Sample Preparation Method for Next-Stage Aggregate Proteomic Analysis. Analytical chemistry. 2019. 91. 21. 13494-13500
  • Tadashi Sawayama, Katsuhiko Nakashima, Tohru Ichimura, Ryuichi Sakai, Takamasa Uekita. Homophilic complex formation of CDCP1 via the extracellular CUB2 domain facilitates SFK activation and promotes cancer cell migration. Oncology reports. 2019. 42. 4. 1507-1516
  • Masato Taoka, Michihiko Fujii, Masahiro Tsuchiya, Takamasa Uekita, Tohru Ichimura. A Sensitive Microbead-Based Organic Media-Assisted Method for Proteomics Sample Preparation from Dilute and Denaturing Solutions. ACS applied materials & interfaces. 2017. 9. 49. 42661-42667
ｍore...
MISC (50)：
  • 中島 克彦, 上北 尚正, 黒澤 仁, 堺 隆一. 転移関連膜タンパク質CDCP1の切断による分泌とその機能(Secretion of cleaved CDCP1, a metastasis-related transmembrane protein, and its biological function). 日本癌学会総会記事. 2014. 73回. P-2176
  • 富山 新太, 上北 尚正, 山口 英樹, 上野 英明, 滝田 順子, 佐々木 一樹, 中川原 章, 森 健太郎, 堺 隆一. 新規ALK結合蛋白質であるFlotillin-1は、ALKの細胞膜結合の調節を介してALKシグナルを制御する(Flotillin-1 regulates oncogenic signaling in neuroblastoma cells by regulating ALK membrane association). 日本癌学会総会記事. 2014. 73回. J-3103
  • 富山 新太, 上北 尚正, 山口 英樹, 佐々木 一樹, 滝田 順子, 中川原 章, 森 健太郎, 堺 隆一. 新規ALK結合蛋白質であるFlotillin-1は、endocytosisを介してALKシグナルを制御する(Flotillin-1 is a novel ALK binding protein which regulates ALK signaling through receptor endocytosis). 日本癌学会総会記事. 2013. 72回. 15-15
  • 富山 新太, 上北 尚正, 山口 英樹, 鎌田 礼子, 佐々木 一樹, 中川原 章, 堺 隆一. 新規ALK結合蛋白質であるFlotillin-1は、endocytosisを介してALKシグナルを制御する(Flotillin-1 is a novel ALK binding protein which regulates ALK signaling through receptor endocytosis). 日本癌学会総会記事. 2012. 71回. 528-528
  • Ryuichi Sakai, Takamasa Uekita. CDCP1 links RAS and Src signaling pathways as a common effector for the promotion of tumor metastasis. CANCER RESEARCH. 2012. 72
ｍore...
Books (1)：
  • 実験医学(10月号) 細胞表層プロテオリシスによる細胞移動の調節
    羊土社 2003
Lectures and oral presentations  (1)：
  • Regulation of metastasis and invasion by a novel Src substrate CDCP1
    (68th Annual Meeting of the Japanese Cancer Association (招待講演) 2009)
Education (3)：
  • 1998 - 2002 The University of Tokyo Graduate School of Medicine
  • 1996 - 1998 The University of Tokyo Graduate School of Agricultural and Life Sciences Animal Resource Sciences
  • 1991 - 1995 Saitama University Faculty of Science Biochemistry
Professional career (2)：
  • M.S. in Agriculture and Life Science (The University of Tokyo)
  • Ph.D. in Medical Science (The University of Tokyo)
Work history (8)：
  • 2013/10 - 現在 National Defense Academy Department of Applied Chemistry, Genome Biology Associate Professor
  • 2012/11 - 2013/09 National Cancer Center Research Institute Division of Metastasis and Invasion Signaling senior Researcher
  • 2012/04 - 2012/10 National Cancer Center Reseach Institute Growth Factor Division senior Researcher
  • 2010/05 - 2012/03 National Cancer Center Reseach Institute Growth Factor Division Staff Scientist
  • 2003/05 - 2008/04 National Cancer Center Research Institute Growth Factor Division
Show all
Awards (4)：
  • 2017/07 - 日本がん転移学会 第26回日本がん転移学会 優秀ポスター賞
  • 2010/07 - 日本がん転移学会 第19回日本がん転移学会 優秀演題賞(口演)
  • 2002/07 - 日本がん転移学会 第11回日本がん転移学会 優秀演題賞(口演)
  • 2001/09 - Institute of Medical Science, University of Tokyo Founding symposium Excellent Research Award
Association Membership(s) (9)：
米国癌学会 ,  日本生化学会 ,  日本分子生物学会 ,  日本がん転移学会 ,  日本癌学会 ,  The Japanese Biochemical Society ,  The Molecular Biology Society of Japan ,  The Japanese Association for Metastasis Research ,  The Japanese Cancer Association
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM