Kurihara Kazuo

クリハラカズオ | Kurihara Kazuo

Affiliation and department：
Job title： Senior Principal Researcher
Homepage URL (2)： http://www.qst.go.jp/ , http://www.qst.go.jp/ENG/tabid72.html

Research field (2)： Quantum beam science , Structural biochemistry

Research keywords (5)： BIX , Protein , Crystallography , Diffractometer , Neutron

Research theme for competitive and other funds (6)：

2019 - 2022 Elucidation of the catalytic mechanism of hydrogenase based on all-atom structure information for the mitigation of global warming
2016 - 2020 Elucidation of reaction mechanism of hydrogenase by neutron crystallography
2010 - 2012 Elucidation of Protein-Ligand Interactions Using Neutron Diffraction
2007 - 2009 Technological improvement for Neutron Crystallographic Analysis of Protein Structures
2006 - 2007 タンパク質のフォールディング、ダイナミクス及び分子認識に関与する水和構造

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Papers (98)：

Takeshi Murakawa, Kazuo Kurihara, Mitsuo Shoji, Naomine Yano, Katsuhiro Kusaka, Yoshiaki Kawano, Mamoru Suzuki, Yasuteru Shigeta, Takato Yano, Motoyasu Adachi, et al. Neutron Crystallography of a Semiquinone Radical Intermediate of Copper Amine Oxidase Reveals a Substrate-Assisted Conformational Change of the Peptidyl Quinone Cofactor. ACS Catalysis. 2023. 12403-12413
Takeshi Hiromoto, Koji Nishikawa, Seiya Inoue, Hideaki Ogata, Yuta Hori, Katsuhiro Kusaka, Yu Hirano, Kazuo Kurihara, Yasuteru Shigeta, Taro Tamada, et al. New insights into the oxidation process from neutron and X-ray crystal structures of an O₂-sensitive [NiFe]-hydrogenase. Chemical Science. 2023
Takeshi Murakawa, Kazuo Kurihara, Motoyasu Adachi, Katsuhiro Kusaka, Katsuyuki Tanizawa, Toshihide Okajima. Re-evaluation of protein neutron crystallography with and without X-ray/neutron joint refinement. IUCrJ. 2022. 9. 3. 342-348
Fumiaki Kono, Kazuo Kurihara, Taro Tamada. Current status of neutron crystallography in structural biology. Biophysics and Physicobiology. 2022
Takeshi Hiromoto, Koji Nishikawa, Seiya Inoue, Hiroaki Matsuura, Yu Hirano, Kazuo Kurihara, Katsuhiro Kusaka, Matthew Cuneo, Leighton Coates, Taro Tamada, et al. Towards cryogenic neutron crystallography on the reduced form of [NiFe]-hydrogenase. Acta crystallographica. Section D, Structural biology. 2020. 76. Pt 10. 946-953

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MISC (146)：

栗原和男, 河野史明, 清水瑠美, 玉田太郎, 田村格良. Current status of neutron diffractometers for protein crystals, BIX-3 and BIX-4. 日本中性子科学会年会講演概要集. 2023. 23rd
栗原和男, 平野優, 廣本武史, 河野史明, 田村格良, 玉田太郎. Updating of neutron diffractometers for protein crystals, BIX-3 and BIX-4. 日本中性子科学会年会講演概要集. 2022. 22nd
玉田太郎, 平野優, 廣本武史, 栗原和男. 生体高分子用中性子単結晶回折装置BIX-3,4の現状. 日本結晶学会年会講演要旨集. 2022. 2022
平野優, 栗原和男, 玉田太郎. Life Science using BIX-3, BIX-4. 波紋. 2022. 32. 1
栗原和男, 玉田太郎. Current Status and Future Prospects of Single Crystal Diffractometers for Bio-Macromolecules, BIX-3 and BIX-4. 波紋. 2021. 31. 1

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Patents (1)：

生体高分子の結晶育成装置

Books (4)：

入門構造生物学 -放射光X線と中性子で最新の生命現象を読み解く-(高エネルギー加速器研究機構構造生物学研究センター編加藤龍一編集)
共立出版 2010
タンパク質結晶の新展開 -新しい育成技術から構造解析・応用研究へ-(監修: 高野和文)
シーエムシー出版 2008
生命科学のための機器分析実験ハンドブック(西村善文 /編)
羊土社 2007
Hydrogen- and Hydration-Sensitive Structural Biology (Nobuo Niimura, Hiroshi Mizuno, John R. Helliwell and Eric Westhof)
KubaPro Co. Ltd 2005

Lectures and oral presentations (5)：

中性子とX線を相補利用したタンパク質構造解析の実際
(大阪大学蛋白質研究所セミナー 2014)
Detailed structure analysis of active site of β-lactamase TOHO-1
(4th International Symposium on Diffraction Structural Biology 2013)
Preparation of D-bovine RNase A
(Human Frontier Science Project Year 1 Symposium 2007)
Neutron Single-crystal Diffractometers Dedicated for Biological Macromolecules at JAEA
(Third Japanese-French seminar on Structural Dynamics on Proteins 2007)
Neutron Diffraction Experiment of Fully Deuterated Proteins
(Human Frontier Science Project kick off Symposium 2006)

Education (3)：

- 1998 Tohoku University Graduate School of Science Doctoral course second term, Department of Physics
- 1995 Tohoku University Graduate School of Science Doctoral course first term, Department of Physics
- 1993 Tohoku University Faculty of Science Department of Physics 2

Professional career (1)：

Ph.D. (Tohoku University)

Work history (11)：

2021/04 - 現在 National Institutes for Quantum Science and Technology Institute for Quantum Life Science, Quantum Life and Medical Science Directorate Senior Principal Researcher
2019/04 - 2021/03 National Institutes for Quantum and Radiological Science and Technology Institute for Quantum Life Science Senior Principal Researcher
2016/04 - 2019/03 National Institutes for Quantum and Radiological Science and Technology Tokai Quantum Beam Science Center Senior Principal Researcher
2015/07 - 2016/03 Japan Atomic Energy Agency Quantum Beam Science Center, Sector of Nuclear Science Research Senior Principal Researcher
2014/04 - 2015/06 Japan Atomic Energy Agency Quantum Beam Science Center, Sector of Nuclear Science Research Assistant Principal Researcher

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Awards (1)：

2009/10 - 独立行政法人日本原子力研究開発機構理事長表彰研究開発功績賞中性子を用いた全原子構造解析による生物化学反応機構の解明

Association Membership(s) (5)：

JAPANESE ASSOCIATION FOR CRYSTAL GROWTH , THE BIOPHYSICAL SOCIETY OF JAPAN , PROTEIN SCIENCE SOCIETY OF JAPAN , THE CRYSTALLOGRAPHIC SOCIETY OF JAPAN , THE JAPANESE SOCIETY FOR NEUTRON SCIENCE

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