Shibata Hiroyuki | Researcher Information

2005 - 2010 筋緊張性ジストロフィ症に関わるタンパク質因子の構造生物学・機能生物化学からの研究
2002 - 2010 ペルオキシソームの形成・細胞内輸送に関わるタンパク質因子の構造生物学・機能生物化学からの研究
2001 - 2006 Structural biological analysis of proteins associated with intracellular translocation of peroxisomal membrane proteins
Structural biological analysis of proteins associated with myotonic dystrophy

Kyoko Egawa, Hiroyuki Shibata, Shun-ichi Yamashita, Hiroya Yurimoto, Yasuyoshi Sakai, Hiroaki Kato. Overexpression and purification of rat peroxisomal membrane protein 22, PMP22, in Pichia pastoris. PROTEIN EXPRESSION AND PURIFICATION. 2009. 64. 1. 47-54
Yasuhiko Sato, Hiroyuki Shibata, Hiroaki Nakano, Yuji Matsuzono, Yoshinori Kashiwayama, Yuji Kobayashi, Yukio Fujiki, Tsuneo Imanaka, Hiroaki Kato. Characterization of the interaction between recombinant human peroxin Pex3p and Pex19p - Identification of Trp-104 in Pex3p as a critical residue for the interaction. JOURNAL OF BIOLOGICAL CHEMISTRY. 2008. 283. 10. 6136-6144
T Shimizu, H Shibata, T Araya, T Nakatsu, K Miyairi, T Okuno, H Kato. Expression, purification, and crystallization of endopolygalacturonase from a pathogenic fungus, Stereum purpureum, in Escherichia coli. PROTEIN EXPRESSION AND PURIFICATION. 2005. 44. 2. 130-135
Kashiwayama, Y, Asahina, K, Shibata, H, Morita, M, Muntau, A. C, Roscher, A. A, Wanders, R. J. A, Shimozawa N, Sakaguchi, M, Kato, H, et al. Role of Pex19p in the targeting of PMP70 to peroxisome. Biochim. Biophys. Acta. 2005. 1746. 2. 116-128
H Shibata, Y Kashiwayama, T Imanaka, H Kato. Domain architecture and activity of human Pex19p, a chaperone-like protein for intracellular trafficking of peroxisomal membrane proteins. JOURNAL OF BIOLOGICAL CHEMISTRY. 2004. 279. 37. 38486-38494

ｍore...

Dap kinase crystals, method of screening candidate for drug targeting dap kinase using the same and drug obtained thereby
Dap kinase crystals, method of screening candidate for drug targeting dap kinase using the same and drug obtained thereby

ABCタンパク質の立体構造研究-現状と課題「ABC蛋白質」(植田和光編)
学会出版センター 2005 ISBN:4762230421

ペルオキシソーム膜タンパク質輸送に関与するPex3pとPex19pの相互作用様式
(日本蛋白質科学会2008年度大会 2008)
Domain Architecture and Activity of Human Pex19p, a Chaperone-like Protein for Intracellular Trafficking of Peroxisomal Membrane Proteins
(International Meeting on the Topogenesis of Organellar Proteins 2004)
ペルオキシソーム膜タンパク質局在化機構の解析-Pex19pのドメイン構造と機能
(理研構造生物シンポジウムIX 2004)
Domain structure and function of human Pex19p, a chaperone-like protein for intracellular trafficking of peroxisomal membrane proteins
(日本生化学会2003年度大会 2003)
ペルオキシソーム膜タンパク質局在化機構の解析-Pex19pのドメイン構造と機能
(日本蛋白質科学会2003年度大会 2003)

ｍore...

Structural analysis of protein associated with circadian clock machinary of cyanobacteria
2002 -
Expression and purification of ABC proteins (MDR1, SUR1) for X-ray crystallography
2001 -
Structural biological analysis of proteins associated with intracellular translocation of peroxisomal membrane proteins
2001 -

- 1998 Kyoto University Graduate School, Division of Agriculture Agricultural Biological Chemistry
- 1997 Kyoto University
- 1994 Kyoto University
- 1992 Kyoto University Faculty of Agriculture

Ph. D. (Agriculture)

National Cerebral and Cardiovascular Center, Research Institute Department of Cardiac Physiology Researcher

日本生化学会 , 日本蛋白質科学会 , The Japanese Biochemical Society , Protein Science Society of Japan , and Agrochemistry , Biotechnology , Japan Society for Bioscience