Rchr
J-GLOBAL ID:200901002537032309   Update date: Mar. 18, 2024

Hirata Masato

ヒラタ マサト | Hirata Masato
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://d.fdcnet.ac.jp/
Research field  (1): Medical biochemistry
Research keywords  (4): Osteocalcin ,  Developmental Origin of Health and Disease ,  Metabolic syndrome ,  Cellular Biochemistry
Research theme for competitive and other funds  (48):
  • 2020 - 2024 Studies on the effect of maternal uncarboxylated osteocalcin on the metabolic properties of next generation
  • 2020 - 2023 骨由来タンパク・オステオカルシンの運動機能向上に関わる新規生理機能の解明
  • 2017 - 2021 Novel drug discovery for dislipidemia
  • 2017 - 2020 Roles of osteocalcin for energy metabolism
  • 2012 - 2017 Analysis of the functional interaction among bone, gut and energy metabolism with a special reference to gender difference
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Papers (206):
  • Takahito Otani, Akiko Mizokami, Hiroshi Takeuchi, Tetsuichiro Inai, Masato Hirata. The role of adhesion molecules in osteocalcin-induced effects on glucose and lipid metabolism in adipocytes. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2024. 1871. 4. 119701-119701
  • Tomoyo Kawakubo-Yasukochi, Yoshikazu Hayashi, Masato Hirata. Effects of Maternal Nutrition on Oral Health in Offspring. Current Oral Health Reports. 2023. 10. 3. 69-74
  • Mineyuki Mizuguchi, Takeshi Yokoyama, Takahito Otani, Shiori Kuribara, Yuko Nabeshima, Takayuki Obita, Masato Hirata, Keiichi Kawano. Structural and mutational analyses of decarboxylated osteocalcin provide insight into its adiponectin-inducing activity. FEBS Letters. 2023. 597. 11. 1479-1488
  • Jing Gao, Akiko Mizokami, Hiroshi Takeuchi, Aonan Li, Fei Huang, Haruki Nagano, Takashi Kanematsu, Eijiro Jimi, Masato Hirata. Phospholipase C-related but catalytically inactive protein acts as a positive regulator of insulin signalling in adipocytes. Journal of Cell Science. 2022. 135. 1
  • Tomoyo Kawakubo-Yasukochi, Ena Yano, Soi Kimura, Takuya Nishinakagawa, Akiko Mizokami, Yoshikazu Hayashi, Yuji Hatakeyama, Kenji Ohe, Atsushi Yasukochi, Seiji Nakamura, et al. Hepatic glycogenolysis is determined by maternal high-calorie diet via methylation of Pygl and it is modified by oteocalcin administration in mice. Molecular Metabolism. 2021. 54. 101360-101360
more...
MISC (32):
  • 溝上顕子, 安河内, 川久保, 友世, 平田 雅人. オステオカルシンと美容. FOOD Style21. 2024. 28. 2. 22-25
  • 溝上 顕子, 安河内(川久保)友世, 大谷 崇仁, 平田 雅人. オステオカルシンのホルモン作用. 糖尿病・内分泌代謝科. 2022. 54. 3. 259-266
  • 平田雅人. 骨と臓器のコミュニケーション〜オステオカルシンの研究から〜. FOOD Style 21. 2021. 25. 9. 8-11
  • 溝上 顕子, 安河内(川久保)友世, 平田 雅人. 骨が支える健康長寿-若返りホルモン「オステオカルシン」を中心に. FOOD Style 21. 2020. 24. 7. 37-39
  • 平田雅人. 骨の作り出すメッセージ物質が免疫力アップ、記憶力アップを促し、若返り効果を生む. 人体 驚異のメカニズム. 2018. 68-70
more...
Books (26):
  • Interface Oral Health Science 2007
    Springer, Tokyo 2007
  • ブレインサイエンス・レビュー2004
    クバプロ 東京 2004
  • 脳機能の解明:生命科学の主潮流
    ガイア出版会 福岡 2002
  • 医科生化学
    2000
  • 医科生化学 (KS医学・薬学専門書)
    2000 ISBN:406153663X
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Lectures and oral presentations  (80):
  • Amelioration of cell number and metabolic features of adipocytes by osteocalcin
    (Journal of Oral Biosciences Supplement (Web) 2020)
  • Functional modulation of myotubes by osteocalcin
    (JOURNAL OF PHARMACOLOGICAL SCIENCES 2015)
  • Acceleration of bone regeneration by local application of lithium: Wnt signal-mediated osteoblastogenesis and Wnt signal-independent suppression of osteoclastogenesis (vol 90, pg 397, 2014)
    (BIOCHEMICAL PHARMACOLOGY 2014)
  • Altered intracellular trafficking of EGFR by extracellular glucose concentration in squamous carcinoma cells
    (FASEB JOURNAL 2014)
  • Scorpion toxin modulates P2X receptor activation in rat cerebral artery myocyte
    (JOURNAL OF PHARMACOLOGICAL SCIENCES 2014)
more...
Education (2):
  • 1976 - 1980 Kyushu University
  • 1970 - 1976 Kyushu University School of Dentistry
Professional career (1):
  • (BLANK) (Kyushu University)
Work history (9):
  • 2017/04 - 現在 Fukuoka Dental College School of Dentistry
  • 2017/04 - 現在 九州大学名誉教授
  • 2015/04 - 2017/03 Kyushu University Faculty of Dental Science
  • 2010/05 - 2017/03 Kyushu University
  • 1996/08 - 2017/03 Kyushu University School of Dentistry
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Committee career (3):
  • 2000 - 歯科基礎医学会 名誉会員
  • 薬理学会 評議員
  • 生化学会 評議員
Awards (3):
  • 2019/02 - 日本歯科医学会 日本歯科医学会会長賞・研究部門
  • 2018/05 - 歯科基礎医学会 平成29年度歯科基礎医学会賞
  • 2002/10 - 第2回歯科基礎医学会ライオン学術賞
Association Membership(s) (3):
歯科基礎医学会 ,  薬理学会 ,  生化学会
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