Uno Yasuhiro

ウノヤスヒロ | Uno Yasuhiro

Affiliation and department：

Research field (1)： Zoological sciences

Research keywords (8)：ゲノム , Veterinary Medicine , Genomics , Molecular Biology , Drug Metabolism , 分子生物学 , 獣医学 , 薬物代謝学

Research theme for competitive and other funds (4)：

2020 - 2023 Systematic identification and characterization of essential drug-metabolizing enzyme toward establishment of platform for drug metabolism research in veterinary species
2005 - 2007 Molecular mechanism of chemical-induced toxicity in fetal livers
2005 - 2006 薬物代謝酵素フラビン含有モノオキシゲナーゼがもたらす薬物相互作用と疾病の個人差
-

Papers (187)：

Yasuhiro Uno, Miaki Makiguchi, Genki Ushirozako, Kyoko Tsukiyama-Kohara, Makiko Shimizu, Hiroshi Yamazaki. Molecular and functional characterization of flavin-containing monooxygenases (FMO1-6) in tree shrews. Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology. 2024. 277
Yasuhiro Uno, Norie Murayama, Hiroshi Yamazaki. Novel Cytochrome P450 2C119 Enzymes in Cynomolgus and Rhesus Macaques Metabolize Progesterone, Diclofenac, and Omeprazole. Drug metabolism and disposition: the biological fate of chemicals. 2024. 52. 3. 266-273
Yasuhiro Uno, Osamu Yamato, Hiroshi Yamazaki. Transcript abundance of hepatic drug-metabolizing enzymes in two dog breeds compared with 14 species including humans. Drug Metabolism and Pharmacokinetics. 2024. 101002-101002
Tomoki Ootawa, Siyuan Wu, Ryoya Sekio, Henry Smith, Md. Zahorul Islam, Ha Thi Thanh Nguyen, Yasuhiro Uno, Mitsuya Shiraishi, Atsushi Miyamoto. Characterization of Vasoreactivity in a Semi-Arboreal Snake, the Tokara Habu (Protobothrops tokarensis). Animals. 2023. 13. 23. 3629-3629
Yasuhiro Uno, Shotaro Uehara, Genki Ushirozako, Tatsunori Masatani, Hiroshi Yamazaki. Chronic Toxoplasma infection affects gene expression of drug-metabolizing enzymes in mouse liver. Xenobiotica; the fate of foreign compounds in biological systems. 2023. 1-6

ｍore...

MISC (28)：

ｍore...

Lectures and oral presentations (23)：

イヌ、ブタ、カニクイザルにおけるチトクロムP450の同定・解析
(第50回日本毒性学会学術年会 2023)
カニクイザルにおける薬物代謝酵素の同定・解析
(第48回日本毒性学会学術年会 2021)
マイクロミニピッグにおける薬物動態関連機能分子の解析
(第43回日本毒性学会学術年会 2016)
実験動物およびヒトの薬物酸化酵素活性の比較
(第42回日本毒性学会学術年会 2015)
カニクイザルにおけるチトクロームP450とグルクロン酸抱合酵素の解析
(第42回日本毒性学会学術年会 2015)

ｍore...

Education (5)：

2008 - Hokkaido University Graduate School of Veterinary Medicine
2001 - 2003 University of Tokyo Institute of Medical Science
1998 - 2001 University of Minnesota, Molecular Veterinary Science
1994 - 1998 University of Massachusetts, Animal Science
1988 - 1994 Hokkaido University Faculty of Veterinary Medicine Department of Veterinary Medicine

Professional career (1)：

Work history (5)：

2019 - 現在 Kagoshima University Joint Faculty of Veterinary Medicine Associate Professor
2017 - 2019 Shin Nippon Biomedical Laboratories, Ltd. Preclinical Research Support Division, Research Planning Unit Unit Leader
2006 - 2017 Shin Nippon Biomedical Laboratories, Ltd. Pharmacokinetics and Bionanalysis Center Unit Leader
2003 - 2006 Hokkaido University Graduate School of Pharmaceutical Science Assistant Professor
2001 - 2003 Shin Nippon Biomedical Laboratories, Ltd.

Awards (4)：

2010 - The Japanese Society for the Study of Xenobiotics Young Investigator’s Awards
1998 - Poultry Science Association Graduate Student Research Certificate of Excellence
1998 - University of Minnesota Animal Biotechnology Center Travel Award
1994 - Yoshida Scholarship Foundation Scholarship

Association Membership(s) (2)：

THE JAPANESE SOCIETY OF VETERINARY SCIENCE , THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page