Rchr
J-GLOBAL ID：200901002908346425   Update date: Feb. 01, 2024

Shimotohno Kunitada

シモトオノ クニタダ | Shimotohno Kunitada
Affiliation and department：
Keio University School of Medicine

About Keio University School of Medicine


Job title： Professor,Director
Research field  (2)： Virology ,  Cell biology
Research keywords  (6)： hepatitis C virus ,  抗ウイルス剤 ,  肝炎 ,  Carcinogenesis ,  Cancer ,  Virus
Research theme for competitive and other funds  (33)：
  • 2010 - 2016 Infection/inflammation-assisted acceleration of the carcinogenic spiral and its alteration though vector conversion of the host response to tumors
  • 2010 - 2015 Prevention of cancer development by hepatitis C virus
  • 2010 - 2014 The role of lipid metabolism on HCV proliferation
  • 1983 - 2010 ヒトT細胞白血病ウィルスによる発がん機構 肝炎ウィルスによる肝発がん
  • 1983 - 2010 Molecular mechanism of carcinogenesis of human T-cell leukemia virus Molecular mechanism of hepatocarcinogenesis by hepatic viruses
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Papers (273)：
  • Koji Fujita, Hironori Nishitsuji, Hisakazu Iwama, Tomoko Tadokoro, Asahiro Morishita, Shima Mimura, Masafumi Ono, Takashi Himoto, Kunitada Shimotohno, Tsutomu Masaki. Pegylated interferon therapy-related microRNA-6126 downregulates sodium taurocholate cotransporting polypeptide expression in hepatocytes. Gene. 2023. 853. 147068-147068
  • Takayuki Murata, Satoko Iwahori, Yusuke Okuno, Hironori Nishitsuji, Yusuke Yanagi, Koichi Watashi, Takaji Wakita, Hiroshi Kimura, Kunitada Shimotohno. N6-methyladenosine Modification of Hepatitis B Virus RNA in the Coding Region of HBx. International journal of molecular sciences. 2023. 24. 3
  • Keigo Yato, Mami Matsuda, Kento Fukano, Tomohisa Tanaka, Kohji Moriishi, Hironori Nishitsuji, Kunitada Shimotohno, Koji Tamura, Takaji Wakita, Masamichi Muramatsu, et al. Identification of neutralizing epitopes in the preS2 domain of the hepatitis B virus. Virus research. 2023. 323. 199014-199014
  • Ayaka Washizaki, Asako Murayama, Megumi Murata, Tomoko Kiyohara, Keigo Yato, Norie Yamada, Hussein Hassan Aly, Tomohisa Tanaka, Kohji Moriishi, Hironori Nishitsuji, et al. Neutralization of hepatitis B virus with vaccine-escape mutations by hepatitis B vaccine with large-HBs antigen. Nature Communications. 2022. 13. 1. 5207-5207
  • Hironori Nishitsuji, Satoko Iwahori, Mariko Ohmori, Kunitada Shimotohno, Takayuki Murata. Ubiquitination of SARS-CoV-2 NSP6 and ORF7a Facilitates NF-κB Activation. mBio. 2022. e0097122
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MISC (108)：
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Patents (6)：
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Education (4)：
  • - 1973 北海道大学大学院 薬学研究科
  • - 1973 Hokkaido University Faculty of Pharmacy
  • - 1967 Tohoku University Faculty of Science Department of Chemistry
  • - 1967 Tohoku University Faculty of Science, Department of Chemistry
Professional career (1)：
  • Doctor of Pharmaceutical Sciences (Hokkaido University)
Work history (6)：
  • 2011/11 - 現在 National Center for Global Health and Medicine Research Center for Hepatitis and Immunology Project Chief
  • 2007/04 - 2011/10 Chiba Institute of Technology Research Institute professor
  • 1996/09 - 2006/03 京都大学ウィルス研教授
  • 1985 - 1996 国立がんセンター研究所部長
  • 1983 - 1985 国立がんセンター研究所室長
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Committee career (5)：
  • 1990 - 日本生化学会 評議員
  • 1990 - The Japanese Biochemical Society Councilor
  • 1987 - 日本癌学会 評議員
  • 1987 - The Japanese Cancer Association Councilor
  • 日本ウイルス学会 会員,第51回日本ウイルス学会学術集会会長(2003)
Awards (4)：
  • 2016/02 - Princess Takamatsu Cancer Research Fund Princess Takamatsu Cancer Research Fund Prizes
  • 2006/09 - Japanese Cancer Association Yoshida Tomizo prie
  • 1997 - 野口英世医学賞
  • 1985 - 日本遺伝学会奨励賞
Association Membership(s) (8)：
日本肝臓学会 ,  日本ウイルス学会 ,  日本分子生物学会 ,  日本生化学会 ,  日本癌学会 ,  The Molecular Biology Society of Japan ,  The Japanese Cancer Association ,  The Japanese Biochemical Society
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