Rchr

J-GLOBAL ID：200901002975855482 Update date: Jan. 31, 2024

Nakajima Jun

ナカジマジュン | Nakajima Jun

Affiliation and department：
Job title： Director
Other affiliations (1)：

The University of Tokyo Graduate School of Medicine, Surgical Sciences, Department of Cardiothoracic Surgery Emeritus Professor

Homepage URL (2)： http://ctstokyo.umin.ne.jp/ , http://www.h.u-tokyo.ac.jp/patient/depts/thoracics_md.html

Research field (1)： Respiratory surgery

Research keywords (1)： Thoracic surgery

Research theme for competitive and other funds (43)：

2022 - 2027 Integrative understanding of cardiac and mediastinal diseases based on the common developmental origins
2021 - 2023 縦隔間葉系の器官発生及び疾患発症における意義の解明
2019 - 2020 Analysis of spatiotemporal heterogeneity in metastatic lung tumors
2018 - 2020 術中迅速蛍光診断のための癌特異的蛍光プローブ開発
2017 - 2020 Development of a Lung Regenaration Model Using Autologous Cells

2017 - 2020 Comprehensive profiling of tumor immune microenvironment for effective personalized lung cancer vaccine

2017 - 2020 Establishment of noninvasive nuclear monitoring for chronic rejection after lung transplantation and development of early therapy

2015 - 2019 Development of lung cancer specific fluorescent probe for post operative recurrence control

2015 - 2018 Development of personalized lung cancer vaccine targeting neoantigens

2015 - 2017 Effects of Perfluorocarbon on the re-perfuion injury of the donor lungs

2014 - 2017 Identification of neoantigens and development of a novel personalized lung cancer treatment targeting passenger mutations

2014 - 2017 Mechanisms of histone-induced lung reperfusion injury after lung transplantation

2013 - 2016 Elucidation of the mechanism of transplanted rejected airways with special reference to innate immunity

2012 - 2016 Chimeric antigen receptor gamma delta T cell immunotherapy for the treatment of malignant mesothelioma

2012 - 2015 Development of cancer vaccine therapy targeting individual genetic mutations identified by next generation sequencing

2010 - 2012 Elucidation of the mechanism of transplanted rejected airways with special reference to epithelial to mesenchymal transition

2009 - 2011 Clinical study on adoptive immunotherapy with autologous gammadelta T-lymphocyte for patients with pulmonary metastasis from colorectal cancer.

2007 - 2008 Construction of the system for lung cancer treatment based onmethylation profile and EGFR mutation

2007 - 2008 Clinical research of a new immunotherapy for the lung cancer : Autologous gamma-delta T-cell adoptive immunotherapy

2005 - 2006 Clinical research on a new immunotherapy for the treatment of non-small cell lung cancer

2002 - 2003 The investigation on the expression regulation and the role on chemosensitivity of a xenobiotic enzyme GSTP1 in lung cancer.

2000 - 2002 Establishment of Tissue Banking System on the basis of regional linkage

2000 - 2001 T-cell receptor遺伝子再構成解析モデルとしての胸腺腫内環境の研究

1999 - 2001 Improved acceptance of homologous aorta by removal of graft dendritic cell

1998 - 1999 Studies on the cellular modulation in cryopreservation focusing the allogenicity of thoracic tissues

1997 - 1999 Studies on the implantation of the heart valves or great vessels utilizing viable xeno-tissues

1997 - 1999 Basic Research for Neonatal Discordant Xeno Heart Transplantation.

1997 - 1998 胸腺腫のリンパ球誘導・分化阻害機構の基礎的研究

1995 - 1997 Co-operative Research on Clinical Application and Functional Preservation of Heart and Heart-lung Transplantation

1994 - 1996 Development of the new monitoring system for acute rejection in clinicallung and lung-heart transplantation, focusing on the cytotoxicity specific to the major histocompatibility complex class I antigens of the donor organ.

1993 - 1996 XENOTRANSPLANTATION OF HEARTS AND LUNGS

1994 - 1995 RESEARCH ON HUMAN AIRWAY EPITHELIUM ACTING AS ALLOANTIGEN-PRESENTING CELLS

1990 - 1992 Basic Research of Heart Lung Transplantation

1987 - 1989 Experimental investigation of heart-lung transplantation

1987 - 1988 肺、縦隔悪性腫瘍の縦隔進展に対する診断確定のための基礎的および臨床的研究

1986 - 1987 胸腺腫のモノクロナール抗体による免疫組織学的解析と臨床的予後に関する基礎的研究

肺移植

胸部悪性腫瘍に対する免疫療法

胸部悪性腫瘍の外科治療学

Lung transplantation

Clinicopathological study on thymic epithelial neoplasms

Study on surgical therapeutics of the lung cancer.

Study on allogenicity of airway epithelium

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Papers (465)：

Meinoshin Okumura, Ichiro Yoshino, Soichiro Funaki, Katsuhiro Okuda, Shun-Ichi Watanabe, Masahiro Tsuboi, Kimihiro Shimizu, Hiroshi Date, Toyofumi F Chen-Yoshikawa, Jun Nakajima, et al. Long-term outcomes following surgical treatment for thymic epithelial tumor in Japan and an analysis of prognostic factors based on the Japanese Association for Research on the Thymus nationwide database. Surgery today. 2023
Jun Nakajima. Is Sublobar Resection Applicable to T1c Non-Small Cell Lung Cancer?. The Annals of thoracic surgery. 2023. 115. 6. 1351-1352
Takahiro Iida, Kazuhiro Nagayama, Kentaro Kitano, Haruo Yamauchi, Minoru Ono, Jun Nakajima. Modified Ravitch procedure for pectus excavatum in Marfan syndrome with annuloaortic ectasia. Interdisciplinary cardiovascular and thoracic surgery. 2023. 36. 6
Jun Nakajima. Minimally Invasive Thymectomy Could Be Attempted for Locally Advanced Thymic Malignancies: A Real-World Study With Propensity Score-Matched Analysis. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2023. 18. 5. 559-560
Hisashi Oishi, Yoshinori Okada, Masaaki Sato, Jun Nakajima, Daisuke Nakajima, Takeshi Shiraishi, Toshihiko Sato, Takashi Kanou, Yasushi Shintani, Kentaroh Miyoshi, et al. Prognostic factors for lung transplant recipients focusing on age and gender: the Japanese lung transplantation report 2022. Surgery today. 2023

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MISC (209)：

Takehiro Tsuchiya, Hideki Kuwano, Takeshi Ito, Masayoshi Nagata, Taketo Kawai, Yumi Tsuboi, Daisuke Matsubara, Isami Okamoto, Kenji Tamura, Jun Nakajima, et al. Novel mechanisms of EGFR-TKI resistance and clonal evolution of lung adenocarcinoma by overexpression of a cell adhesion molecule, CADM1. CANCER RESEARCH. 2020. 80. 21
Kentaro Kitano, Yoshikazu Shinohara, Masako Ikemura, Takahiro Karasaki, Kazuhiro Nagayama, Masaaki Sato, Masaki Anraku, Jun Nakajima. [Reexpansion Pulmonary Edema and Atrial Fibrillation after Resection of a Giant Solitary Fibrous Tumor of the Pleura]. Kyobu geka. The Japanese journal of thoracic surgery. 2019. 72. 12. 997-1000
孫長博, 長山和弘, 長岡孝治, 細井亮宏, 垣見和宏, 中島淳. マウス肺癌LLC-1をモデル系とした新生抗原の網羅的解析(The neoantigen landscape of murine lung cancer LLC-1 model). 日本がん免疫学会総会プログラム・抄録集. 2019. 23回. 83-83
Takeshi Ito, Atsuko Nakamura, Ichidai Tanaka, Yumi Tsuboi, Teppei Morikawa, Jun Nakajima, Daiya Takai, Masashi Fukayama, Yoshitaka Sekido, Toshiro Niki, et al. CADM1 associates with Hippo pathway core kinases; membranous co-expression of CADM1 and LATS2 in lung tumors predicts good prognosis. Cancer science. 2019. 110. 7. 2284-2295
唐崎隆弘, 篠原義和, 北野健太郎, 長山和弘, 佐藤雅昭, 垣見和宏, 中島淳. Spread through air spaces(STAS)を有する非小細胞肺癌に対する次世代シーケンスデータ解析. 日本呼吸器外科学会雑誌. 2019. 33. 3. RO1-5

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Education (2)：

1992 - 学位記(東京大学博士(医学))
- 1982 The University of Tokyo Faculty of Medicine School of Medicine

Professional career (2)：

(BLANK)
M.D.

Work history (2)：

2023/04 - 現在 Japanese Red Cross Medical Center Director
2011/04 - 2023/03 Graduate School of Medicine, The University of Tokyo Department of Thoracic Surgery, Graduate School of Medicine Professor

Committee career (15)：

2018/04 - 現在日本外科学会代議員
2017/05 - 現在日本呼吸器外科学会理事
2021/06 - 2023/06 The Japan Society for The Japan Society for Respiratory Endoscopy Council
2012/11 - 2022/12 日本肺癌学会理事
2021/11 - 2022/10 The Japan Association for Thoracic Surgery (JATS) Congress President, the 75th JATS Annual Meeting

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Awards (1)：

1996 - 日経BP技術賞

Association Membership(s) (6)：

The Japan Society for Transplantation , 日本呼吸器学会 , 日本肺癌学会 , 日本呼吸器外科学会 , 日本胸部外科学会 , 日本外科学会

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