Nakamura Orie

ナカムラオリエ | Nakamura Orie

Affiliation and department：
Job title： Research Associate

Research field (6)： Animals: biochemistry, physiology, behavioral science , Environmental effects of chemicals , Environmental effects of radiation , Biological resource conservation , Veterinary medicine , Molecular biology

Research keywords (8)： Tokudaia muenninki , Diplothrix legata , Apodemus speciosus , Reproduction system , Endometrium , CTLA-2α , Nuclear Cathepsin L , reproductive immunology

Research theme for competitive and other funds (6)：

2011 - 2014 妊娠子宮における核カテプシンLの機能と核移行メカニズムの解析
2010 - 2011 妊娠子宮脱落膜CTLA-2αおよびカテプシンLの細胞質-核輸送メカニズムと核における機能解析
2007 - 2008 マウス子宮内膜脱落膜化における新規システインインヒビター Cytotoxic T lymphocyte associated protein (CTLA)-2αの作用機序
2004 - 2006 Antiphospholipid syndrome : Elucidation of molecular mechanism to give insights into new therapeutic approach
Differentiation of the uNK cells

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Papers (17)：

Takushi Fujimoto, Orie Nakamura, Michiko Saito, Akio Tsuru, Masaki Matsumoto, Kenji Kohno, Kenji Inaba, Hiroshi Kadokura. Identification of the physiological substrates of PDIp, a pancreas-specific protein disulfide isomerase family member. Journal of biological chemistry. 2018
Orie Nakamura, Satoru Moritoh, Kota Sato, Shigeto Maekawa, Namie Murayama, Noriko Himori, Kazuko Omodaka, Tetsuya Sogon, Toru Nakazawa. Bilberry extract administration prevents retinal ganglion cell death in mice via the regulation of chaperone molecules under conditions of endoplasmic reticulum stress. Clinical Ophthalmology. 2017. 11. 1825-1834
Masayuki Yasuda, Yuji Tanaka, Kazuko Omodaka, Koji M. Nishiguchi, Orie Nakamura, Satoru Tsuda, Toru Nakazawa. Transcriptome profiling of the rat retina after optic nerve transection. SCIENTIFIC REPORTS. 2016. 6
Kazuko Omodaka, Takuji Kurimoto, Orie Nakamura, Kota Sato, Masayuki Yasuda, Yuji Tanaka, Noriko Himori, Yu Yokoyama, Toru Nakazawa. Artemin Augments Survival and Axon Regeneration in Axotomized Retinal Ganglion Cells. JOURNAL OF NEUROSCIENCE RESEARCH. 2014. 92. 12. 1637-1646
Kazuko Omodaka, Koji M. Nishiguchi, Masayuki Yasuda, Yuji Tanaka, Kota Sato, Orie Nakamura, Kazuichi Maruyama, Toru Nakazawa. Neuroprotective effect against axonal damage-induced retinal ganglion cell death in apolipoprotein E-deficient mice through the suppression of kainate receptor signaling. BRAIN RESEARCH. 2014. 1586. 203-212

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MISC (1)：

中澤徹, 國方彦志, 横倉俊二, 丸山和一, 西口康二, 高橋秀肇, 国松志保, 劉孟林, 檜森紀子, 田中佑治, et al. 眼疾患メカニズムの新しい理解失明ゼロを目指して. 日本眼科学会雑誌. 2015. 119. 3. 168-194

Lectures and oral presentations (21)：

ビルベリーアントシアニンはERシャペロン調節を介して網膜神経節細胞死を抑制する
(第87回日本生化学会大会 2014)
妊娠成立にむけてダイナミックに変化する子宮内膜~プロテアーゼ調節から見る子宮内膜脱落膜化~
(京都産業大学生命科学セミナー 2013)
プロゲステロン刺激によって脱落膜化する子宮内膜間質細胞株の樹立
(第27回日本生殖免疫学会総会 2012)
カテプシンLは調節因子CTLA-2αと結合することで転写因子CDP/Cux cleavageを変化させている
(第84回日本生化学会大会 2011)
The nuclear transported cathepsin L is stabilized by binding to the regulatory protein CTLA-2alpha and contributes to the maintenance of pregnancy via regulation of placental lactogen expression in murine endometrial stromal cells.
(GCOE International Symposium on Organelle Network 2010)

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Education (1)：

- 1998 Azabu University Faculty of Veterinary Medicine

Professional career (1)：

博士(獣医学) (山口大学)

Work history (2)：

2018/04 - 現在 National Institute for Environment Studies Center for Environmental Biology and Ecosystem Research associate
1998 - 2000 National Cancer Center Research Institute, fellow assistant

Awards (1)：

2003 - 日本生殖免疫学会学会賞

Association Membership(s) (2)：

日本生化学会 , 日本獣医学会

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