Rchr
J-GLOBAL ID：200901003142864530
Update date: Oct. 01, 2022
RIKA OBATA
オバタ リカ | RIKA OBATA
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Research theme for competitive and other funds (9)：
2014 - 2015 ホタルルシフェラーゼ発光メカニズムの解明
2014 - 2015 キラルな有機化合物の合成と構造の解析
2005 - 2006 生物活性を有する環状イソジロシン化合物の開発と応用
2005 - 2006 環状イソジチロシン化合物の合成研究
2005 - 2005 Synthesis and antibacterial activity of cyclic isodityrosine tripeptides (Pacifichem 2005)
2001 - 2002 バーチャル化合物構造データベースの構築
1997 - 1999 抗痴呆症薬の分子設計と合成
1995 - 1997 コレステロール代謝阻害剤pyripyropeneの薬化学的研究
Discovery of halogenated eurypamide B analogues as inhibitors of lipid droplet accumulation in macrophages
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Papers (49)：
Masahiro Kiyama, Satoshi Iwano, Satoshi Otsuka, Shijia W. Lu, Rika Obata, Atsushi Miyawaki, Takashi Hirano, Shojiro A. Maki. Quantum yield improvement of red-light-emitting firefly luciferin analogues for in vivo bioluminescence imaging. Tetrahedron. 2018. 74. 6. 652-660
Daisuke Yasuda, Akihiro Yuasa, Rika Obata, Mao Nakajima, Kyoko Takahashi, Tomoyuki Ohe, Yoshinobu Ichimura, Masaaki Komatsu, Masayuki Yamamoto, Riyo Imamura, et al. Discovery of benzo[g]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2017. 27. 22. 5006-5009
Daisuke Yasuda, Mao Nakajima, Akihiro Yuasa, Rika Obata, Kyoko Takahashi, Tomoyuki Ohe, Yoshinobu Ichimura, Masaaki Komatsu, Masayuki Yamamoto, Riyo Imamura, et al. Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein interaction inhibitors and their inhibitory activity. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2016. 26. 24. 5956-5959
Tetsuya Saito, Yoshinobu Ichimura, Keiko Taguchi, Takafumi Suzuki, Tsunehiro Mizushima, Kenji Takagi, Yuki Hirose, Masayuki Nagahashi, Tetsuro Iso, Toshiaki Fukutomi, et al. p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming. NATURE COMMUNICATIONS. 2016. 7
Masahiro Kiyama, Ryohei Saito, Satoshi Iwano, Rika Obata, Haruki Niwa, Shojiro A. Maki. Multicolor Bioluminescence Obtained Using Firefly Luciferin. CURRENT TOPICS IN MEDICINAL CHEMISTRY. 2016. 16. 24. 2648-2655
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MISC (10)：
OBATA RIKA. Caution in an Experiment of Electroless Nicckel Plating on Glass. 慶應義塾大学日吉紀要 自然科学. 2018. 63. 15-25
OBATA RIKA. What the Rf means in Paper Chromatography. 慶應義塾大学日吉紀要 自然科学. 2016. 60. 60. 7-15
OBATA RIKA. Traffic signal reaction and decoloration of indigo carmine in an aqueous solution. 慶應義塾大学日吉紀要 自然科学. 2016. 59. 59. 21-33
OBATA RIKA. バルマーランプのスペクトルとスピロピラン化合物のフォトクロミズム. 慶應義塾大学日吉紀要 自然科学. 2012. 52. 52. 1-18
OBATA RIKA. 無電解めっきとフォトレジストを用いた鏡の作成. 慶應義塾大学日吉紀要 自然科学. 2012. 52. 52. 19-35
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Patents (10)：
Naphthoquinone derivatives and G1 phase progression inhibitors, bactericides, imipenem activity enhancers, infectious disease inhibitors, etc., containing them.
ナフトキノン誘導体化合物
Preparation of cyclic isodityrosine derivatives having an imipenem-potentiating effect and a cholesteryl ester formation inhibiting activity.
環状イソジチロシン誘導体
Imine derivative and amide derivative
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Books (1)：
天然物化学-植物編
アイピーシー 2007 ISBN:9784901493024
Lectures and oral presentations (76)：
Cathodic Reduction of Acetophenone Using a Boron-Doped Diamond
(German Japanese Symposium on Electrosynthesis 2017 (GJSE-7) 2017)
Innovation of New Luciferin Analog for in vivo Optical Imaging
(World molecular Imaging Congress 2017 2017)
SYNTHESIS AND BIOLUMINESCENCE OF HETEROCYCLIC ANALOGUES OF FIREFLY LUCIFERIN
(17th Asian Chemical Congress & 19th General Assembly of FACS 2017)
ナフタレン骨格を有する選択的Keap-1-リン酸化p62阻害剤の創製研究
(第34回メディシナルケミストリーシンポジウム 2016)
Development of novel inhibitors for Keap1-Nrf2 and Keap1-p62 protein-protein interaction.
(The Society for Redox Biology and Medicine's 23rd Annual Meeting (SFRBM2016) 2016)
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Works (4)：
キラルな有機化合物の合成と構造の解析-Hitoshi Research Portfolio 2016
Rika Obata, Shigeru Ohba 2016 - 2016
「生物活性分子の化学」1回担当(テーマ:酵素阻害剤)
OBATA RIKA 2005 - 2005
科学探究ゼミナール2005 テーマ:「紅茶を飲むとなぜ眠れない?-カフェインの精製」担当
OBATA RIKA 2005 - 2005
共同研究(Johns Hopkins大、米国)
OBATA RIKA
Education (1)：
- 1986 Keio University 理工学部 化学科
Professional career (1)：
博士(理学) (Keio University)
Committee career (8)：
日本化学会 会員
The Chenmical Society of Japan Member
日本薬学会 会員
The Pharmaceutical Society of Japan Member
アメリカ化学会 会員
American Chemical Society Member
有機合成化学協会 会員
The Society of Synthetic Organic Chemistry, Japan Member
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Association Membership(s) (4)：
The Chenmical Society of Japan
, The Pharmaceutical Society of Japan
, American Chemical Society
, The Society of Synthetic Organic Chemistry, Japan
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