2019 - 2022 Study on the amino acid signaling via transporters and receptors for the pharmacologic control of cellular metabolism
2018 - 2020 Study on the effects of amino acid availability on life span and the underlying molecular mechanisms
2015 - 2018 Regulation of cellular metabolism and functions mediated by amino acid transporters and the mechanisms of action of their inhibitors
2015 - 2017 The role of Ubiquitin-Proteasome system in the kidney injury and regeneration
2015 - 2017 Investigation of a novel lipase-like transmembrane protein for the discovery of drugs to regulate the epidermal barrier function
2014 - 2017 Chemo-resistance of xCT expression in NSCLC
2014 - 2015 Identification of a Vesicle specific D-serine transporter in the brain.
2012 - 2015 Identification and the physiological role of a cystine transporter
2012 - 2015 Identification and characterization of a membrane protein TRAP involved in Fanconi syndrome like symptoms.
2012 - 2014 Identification of plasma membrane leucine receptor and elucidation of its link to mTOR signaling pathway
2010 - 2012 Application of F-18-FMT PET for amino acid transporter targetedcancer therapy
2010 - 2011 Signaling mechanisms of a novel-type transmembrane receptor 4F2hc
2009 - 2011 Roles of a novel kidney-specific prostaglandin(PG) transporter in local PG clearance in renal cortex and its pathological relevance
2009 - 2011 New drug development for hyperuricemia targeting novel urate efflux transporter URATv1
2005 - 2010 Transportsome on biomembrane systems: its molecular assembly and physiological function.
2007 - 2009 Identification and functional characterization of plasma membrane amino acid sensors
2005 - 2009 Organic solute transportsomes: their molecular assembly and functional significance
2006 - 2007 Role of System LAmino Acid Transporter in Podocyte Cell Biology
2006 - 2007 Role of a novel prostaglandin transporter OAT-PG in sodium transport regulation mechanism
2005 - 2006 Study on_the protein-protein interaction regulating the function of amino acid transporters
2003 - 2004 Regulatory mechanism of urate transport function by urate transporter binding protein PDZK1
2002 - 2004 Development of novel anti-uricosuric agents based on the genomic strategy.
2001 - 2004 Analysis of Expression of LAT1 in Childhood Leukemia and Effect of Inhibitors on Proliferation Inhibition
2001 - 2004 Genetic Abnormality of Renal Proximal Tubule-Specific Transporters as Causes of Sudden Death Syndrome in South-Eastern Asia
2000 - 2004 Analysis of the vectorial transport of amino acid and drugs in epithelial cells.
2003 - 2003 リバースオンコロジー;がん胎児性LAT1抑制薬による遺伝子変化の網羅的解析
2003 - 2003 腫瘍関連抗原4F2重鎖(CD98)のmTORを介するシグナル機構の解明
2002 - 2003 Identification and functional characterization of all the genes of heterodimeric amino acid transporter family by means of whole genome information
1994 - Award from International Academy for Biomedical and Drug Research in 1994: Special Recognition of Excellence.
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Association Membership(s) (16)：
がん分子標的治療研究会
, 米国細胞生物学会
, 米国神経科学会
, 米国生化学分子生物学会
, 日本腎臓学会
, 日本毒性学会(評議員)
, 日本蛋白質科学会
, 日本細胞生物学会
, 日本分子生物学会
, THE JAPANESE BIOCHEMICAL SOCIETY
, 日本薬理学会(評議員)
, THE JAPANESE CANCER ASSOCIATION
, 米国腎臓学会
, THE JAPAN DIABETES SOCIETY
, THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS
, 米国薬理学会
