Kadowaki Hisae

カドワキヒサエ | Kadowaki Hisae

Affiliation and department：

Research field (1)： Cell biology

Research theme for competitive and other funds (9)：

2022 - 2025 病態脳における小胞体プロテオスタシス破綻によるコレステロール合成不全と脳萎縮
2021 - 2024 小胞体ストレスにおける予防的品質管理の分子機構の解明
2018 - 2021 小胞体ストレスによる新規合成タンパク質の分解機構の解明
2015 - 2018 口腔領域マクロファージにおける小胞体ストレスシグナルを介した炎症病態機構の解明
2013 - 2015 Development of ER quality monitoring probe to characterize the oral tissue disease

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Papers (21)：

Takashi Sugiyama, Naoya Murao, Hisae Kadowaki, Hideki Nishitoh. Chemical chaperones ameliorate neurodegenerative disorders in Derlin-1-deficient mice via improvement of cholesterol biosynthesis. Scientific reports. 2022. 12. 1. 21840-21840
Takashi Sugiyama, Naoya Murao, Hisae Kadowaki, Keizo Takao, Tsuyoshi Miyakawa, Yosuke Matsushita, Toyomasa Katagiri, Akira Futatsugi, Yohei Shinmyo, Hiroshi Kawasaki, et al. ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function. iScience. 2021. 24. 7. 102758-102758
Hironori Kato, Kohki Okabe, Masato Miyake, Kazuki Hattori, Tomohiro Fukaya, Kousuke Tanimoto, Shi Beini, Mariko Mizuguchi, Satoru Torii, Satoko Arakawa, et al. ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue. Life science alliance. 2020. 3. 3
Hisae Kadowaki, Pasjan Satrimafitrah, Yasunari Takami, Hideki Nishitoh. Molecular mechanism of ER stress-induced pre-emptive quality control involving association of the translocon, Derlin-1, and HRD1. Scientific Reports. 2018. 8. 1. 7317
Kadowaki H, Nishitoh H. Endoplasmic reticulum quality control by garbage disposal. FEBS Journal. 2018. 286. 2. 232-240

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MISC (5)：

Books (4)：

Lectures and oral presentations (30)：

小胞体の予防的品質管理における新規合成タンパク質の分解機構
(第39回日本分子生物学会年会 2016)
小胞体の予防的品質管理における新規合成タンパク質の分解機構
(第39回日本分子生物学会年会 2016)
Molecular mechanism of newly synthesized protein degradation in ER stress-induced preemptive quality control
(EMBO Conference 2016)
Molecular mechanism of newly synthesized protein degradation in ER stress-induced preemptive quality control
(EMBO Conference 2016)
小胞体の予防的品質管理における新規合成タンパク質の分解機構
(第11回小胞体ストレス研究会 2016)

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Education (2)：

Professional career (1)：

Work history (6)：

2018/10/01 - 現在 University of Miyazaki Faculty of Madicine School of Madicine Function control study course function biochemistry field
2012/12 - 現在 University of Miyazaki Faculty of Madicine School of Madicine Function control study course function biochemistry field Assistant Professor
2012/04/01 - 2012/11/30 University of Miyazaki Faculty of Madicine School of Madicine Function control study course function biochemistry field
2009/04 - 2012/03 The University of Tokyo Graduate School of Pharmaceutical Sciences
2008/04 - 2009/03 The University of Tokyo Graduate School of Pharmaceutical Sciences

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Awards (6)：

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Association Membership(s) (2)：

日本生化学会 , 日本分子生物学会

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