Hosoya Osamu

ホソヤオサム | Hosoya Osamu

Affiliation and department：
Job title： Assistant Professor
Homepage URL (1)： https://pxy-www.a.okayama-u.ac.jp/user/mnb/Top.html

Research field (2)： Cell biology , Neuroscience - general

Research keywords (2)：細胞生物学 , Cell Biology

Research theme for competitive and other funds (9)：

2021 - 2024 網膜視細胞におけるトポイソメラーゼIIβの生理、病理学的役割の検証
2018 - 2021 岡山大学方式人工網膜(OURep)の製造品質管理とfirst-in-human医師主導治験
2011 - 2014 Roles of type II DNA topoisomerase in the interaction of distant genomic sites
2013 - 2014 SP120による知的障害関連遺伝子の発現制御
2010 - 2012 LA遺伝子の発現と精神・神経疾患

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Papers (10)：

Toshihiko Matsuo, Chaomulige, Mary Miyaji, Osamu Hosoya, Akira Saito, Kazuyuki Nakazono. Candidate Genes in Testing Strategies for Linkage Analysis and Bioinformatic Sorting of Whole Genome Sequencing Data in Three Small Japanese Families with Idiopathic Superior Oblique Muscle Palsy. International Journal of Molecular Sciences. 2022. 23. 15. 8626-8626
Shihui Liu, Mary Miyaji, Osamu Hosoya, Toshihiko Matsuo. Effect of NK-5962 on Gene Expression Profiling of Retina in a Rat Model of Retinitis Pigmentosa. International Journal of Molecular Sciences. 2021. 22. 24. 13276-13276
Osamu Hosoya, Myung Chung, Satoshi Ansai, Hideaki Takeuchi, Mary Miyaji. A modified Tet-ON system minimizing leaky expression for cell-type specific gene induction in medaka fish. Development, growth & differentiation. 2021
Shihui Liu, Toshihiko Matsuo, Mary Miyaji, Osamu Hosoya. The Effect of Cyanine Dye NK-4 on Photoreceptor Degeneration in a Rat Model of Early-Stage Retinitis Pigmentosa. Pharmaceuticals (Basel, Switzerland). 2021. 14. 7
Mary Miyaji, Ryohei Furuta, Osamu Hosoya, Kuniaki Sano, Norikazu Hara, Ryozo Kuwano, Jiyoung Kang, Masaru Tateno, Kimiko M. Tsutsui, Ken Tsutsui. Topoisomerase IIβ targets DNA crossovers formed between distant homologous sites to induce chromatin opening. Scientific Reports. 2020. 10. 1

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MISC (39)：

宮地まり, 河野真二, 細谷修, 竹内秀明, 筒井公子, 筒井研. メダカDNAトポイソメラーゼIIβによる神経系の遺伝子発現制御. 第44回日本分子生物学会年会抄録. 2021
細谷修, Chung Myung, 安齋賢, 竹内秀明, 宮地まり. 改良型Tet-ONシステムを用いたメダカ網膜桿体特異的な遺伝子発現誘導. 第44回日本分子生物学会年会抄録. 2021
Shihui Liu, Toshihiko Matsuo, Mary Miyaji, Osamu Hosoya. Prevention of apoptotic photoreceptor cell death by a Cryptocyanine drug (NK-4) during inherited retinal degeneration in RCS rats. ARVO 2020 Annual Meeting Abstract. 2020. 61. 7
Chaomulige, Toshihiko Matsuo, Shihui Liu, Mary Miyaji, Osamu Hosoya, Izuho Hatada, Takuro Horii. A new knock-out mouse model (MGST2 gene knock-out) for strabismus. ARVO 2020 Annual Meeting Abstract. 2020. 61. 7
Mary Miyaji, Ryohei Furuta, Osamu Hosoya, Kuniaki Sano, Kimiko M. Tsutsui, Ken Tsutsui. Topoisomerase IIβ targets DNA crossovers formed between distant homologous sites to modulate chromatin structure and gene expression. 2019

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Patents (1)：

Lectures and oral presentations (54)：

A modified Tet-ON system minimizing leaky expression for cell-type specific gene induction in medaka fish
(2021)
Regulation of neuronal gene expressions by Medaka DNA topoisomerase IIβ
(2021)
Prevention of apoptotic photoreceptor cell death by a Cryptocyanine drug (NK-4) during inherited retinal degeneration in RCS rats
(ARVO Annual Meeting 2020)
A new knock-out mouse model (MGST2 gene knock-out) for strabismus
(ARVO Annual Meeting 2020)
Topoisomerase IIβ targets DNA crossovers formed between distant homologous sites to modulate chromatin structure and gene expression
(2019)

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Education (4)：

Professional career (1)：

Work history (3)：

2005 - 現在岡山大学大学院医歯薬学総合研究科生体制御科学専攻助教
1998/04 - 2005/03 Okayama University
2005 - - Assistant Professor,Dept. Neurogenomics, Grad. Sch. Med. Dent. Pharm. Sci., Okayama Univ.,Biophysiological Sciences,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University

Awards (2)：

Association Membership(s) (3)：

日本神経科学学会 , 日本生化学会 , 分子生物学会

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