Toyoshima Yuka

スズキユカ (トヨシマユカ) | Toyoshima Yuka

Affiliation and department：

Research field (1)： Food sciences

Research keywords (8)：脂肪肝 , 翻訳調節 , インスリン受容体基質 , 内分泌・代謝学 , 分子栄養学 , タンパク質栄養 , インスリン様成長因子 , インスリン

Research theme for competitive and other funds (6)：

2022 - 2025 The study on the physiological role of the increase in hepatic insulin receptor substrate-2 under protein deprivation
2019 - 2022 Study on the mechanisms by which the translation initiation regulating factors induces lipid accumulation in rat liver under protein deprivation.
2016 - 2019 The physiological significance of eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) on lipid accumulation in rat liver under protein deprivation.
2008 - 子宮内発育不全モデルのキャッチアップ成長・肥満誘導機構の解明:インスリン様シグナル増強の役割
2007 - タンパク質栄養状態に応答した中枢・末梢組織におけるIGF・インスリンシグナルの調節機構と生理活性の制御

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Papers (34)：

Hiroki Nishi, Kaito Uchida, Maki Saito, Daisuke Yamanaka, Haruka Nagata, Hinako Tomoshige, Ichiro Miyata, Koichi Ito, Yuka Toyoshima, Shin-Ichiro Takahashi, et al. Essential Amino Acid Intake Is Required for Sustaining Serum Insulin-like Growth Factor-I Levels but Is Not Necessarily Needed for Body Growth. Cells. 2022. 11. 9
石川真由美, 豊村順子, 八木孝, 田口雄亮, 立花利公, 中田朋子, 豊島由香, 杉原仁, 南史朗. 成長ホルモンによるXBP-1の発現と膵島の形態維持について. 糖尿病. 2021. 64. Suppl.1. I-4
高橋伸一郎, 伯野史彦, 山中大介, 竹中麻子, 豊島由香, 中林靖. 学際研究で切り拓く脂質とアミノ酸のメタボダイナミズムアミノ酸シグナルによる物質代謝制御. 日本生化学会大会プログラム・講演要旨集. 2020. 93回. [2S09m-04]
内田海登, 豊島由香, 伯野史彦, 高橋伸一郎, 竹中麻子. 低タンパク質食摂取で生じるマウスの成長遅滞はInsulin-like Growth Factor-1(IGF-1)投与により抑制される. アミノ酸研究. 2020. 13. 2. 105-105
Yuka Toyoshima, Katsuyuki Nakamura, Reiko Tokita, Naomi Teramoto, Hidetoshi Sugihara, Hisanori Kato, Keitaro Yamanouchi, Shiro Minami. Disruption of insulin receptor substrate-2 impairs growth but not insulin function in rats. JOURNAL OF BIOLOGICAL CHEMISTRY. 2020. 295. 33. 11914-11927

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MISC (22)：

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Lectures and oral presentations (36)：

An increase in 4E-BP1 level mediates to enhance triglyceride accumulation in rat liver under protein malnutrition
(IUNS 21st ICN International Congress of Nutrition 2017)
低タンパク質栄養による肝臓脂質蓄積機構 -新規メカニズムの探索-
(第71回日本栄養・食糧学会大会 2017)
低タンパク質栄養によるインスリン活性増強機構とその生理的意義
(日本アミノ酸学会10周年記念大会 2016)
低タンパク質栄養に応答して起こる褐色脂肪組織の脱共役タンパク質UCP1量の増加とエネルギー消費の亢進
(第70回日本栄養・食糧学会大会 2016)
Protein malnutrition increases the amount and phosphorylation of 4E-binding protein 1 (4E-BP1) to accumulate lipid in rat liver.
(12th Asian Congress of Nutrition 2015)

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Education (3)：

1999 - 2002 The University of Tokyo Graduate School, Division of Agriculture
1997 - 1999 Ochanomizu University Faculty of Life Science
1993 - 1997 Ochanomizu University Faculty of Human Life and Environmental Sciences

Professional career (1)：

Work history (7)：

2021/07 - 現在 Utsunomiya University School of Agriculture Department of Agrobiology and Bioresources Associate Professor
2020/05 - 2021/06 Ochanomizu University Institute for Human Life Innovation Project Associate Professor
2015/04 - 2020/04 Nippon Medical School Institute for Advanced Medical Sciences Assistant Professor
2014/10 - 2015/03 Nippon Medical School
2008/04 - 2014/09 Nippon Medical School

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Committee career (3)：

Awards (5)：

Association Membership(s) (6)：

日本生化学会 , American Society for Nutrition , 日本栄養・食糧学会 , JAPANESE SOCIETY FOR AMINO ACID SCIENCES , 日本内分泌学会 , 日本農芸化学会

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