Nemoto Tetsuhiro

ネモトテツヒロ | Nemoto Tetsuhiro

Affiliation and department：
Job title： professor
Homepage URL (1)： http://www.p.chiba-u.ac.jp/lab/yakka/index.html

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (1)：合成化学

Research theme for competitive and other funds (26)：

2022 - 2026 安定分子構造の直接的な変換・官能基化を活用した革新的有機合成法の開発と展開
2021 - 2023 Development of new BNCT sensitizer based on molecular chirality recognition of amino acid transporter LAT
2020 - 2022 Organic Synthesis using a direct S0-Tn Transition based on Internal Heavy Atom Effect: Application to Photo Reactions
2018 - 2022 Development and Application of Novel Organic Synthesis Methods Based on Dearomatization-Rearomatization Processes
2019 - 2021 化学触媒・酵素触媒プロセスの融合による生物活性天然物・医薬品の効率合成

2018 - 2021 銀カルベノイドを活用した新しい有機合成法の開発と展開

2019 - 創薬研究に資するポリスピロ化合物の新規合成法開発と展開

2016 - 2018 Novel Development of an Amide Insertion Reaction and an Elucidation of metallic Property of Carbenoid Species

2016 - 2018 Development of platform for cancer epigenetic therapy by region-specific inhibition of epigenomic alteration

2015 - 2018 Development of Frieden-Crafts type reactions and their applications to heterocyclic molecule syntheses

2018 - 銀カルベノイドを活用する脱芳香化反応の展開と創薬有用分子合成への応用

2014 - 2017 Selective modification of histone methylation using DNA binding-small molecules

2017 - 未開拓創薬有用天然物:ドラグマシジンE の不斉全合成研究

2014 - 2016 キラルアミン触媒を用いる不斉アジリジン化を基盤とした生物活性化合物合成

2014 - 2015 3,4位縮環インドール類の革新的合成法開発を基盤とする新規創薬シーズの発掘

2015 - ドラグマシジンEの全合成を基盤とした医薬化学研究

2015 - 3,4位中員環縮環インドール類の効率合成法の開発

2014 - 3,4位縮環インドール類の革新的合成法開発を基盤とする新規創薬シーズの発掘

2012 - 含窒素有機分子の革新的合成法の開発と応用

2009 - 2010 Developments and applications of multifunctional catalytic molecules based on the creation of novel asymmetric reaction space

2010 - フェノール類のipso-Friedel-Crafts型反応と関連する有機合成化学についての網羅的研究

2008 - 2009 ジアミノホスフィンオキシドを基盤とする高性能遷移金属触媒の開発

2006 - 2008 Innovative Synthesis of Nitrogen-Containing Organic Compounds Using Diaminophpsphine Oxides and Multicatalytic Reaction Processes

2007 - 2007 ジアミドホスファイト型多金属含有不斉触媒の開発

2004 - 2005 新規機能性リン配位子:ジアミノホスフィンオキシドを用いる実践的触媒的不斉合成

2002 - 2002 α,β-エポキシエステルの実践的触媒的不斉合成-ジルチアゼム、ポリオールへの展開

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Papers (136)：

Masaya Nakajima, Sho Nagasawa, Keita Yamazaki, Tomohiro Yazawa, Honoka Yoneyama, Yuko Kotaka, Tetsuhiro Nemoto. Direct S0 → Tn Transition under Visible Light Irradiation Enabling Synthesis of a Pseudoindoxyl Scaffold. Organic Letters. 2024
Shingo Harada, Hiroki Takenaka, Tsubasa Ito, Haruki Kanda, Tetsuhiro Nemoto. Valence-isomer selective cycloaddition reaction of cycloheptatrienes-norcaradienes. Nature Communications. 2024
Keita Yamazaki, Yuma Okuda, Akiko Takaya, Tetsuhiro Nemoto. Total Synthesis of Dragmacidins G and H. Organic Letters. 2024. 26. 3. 670-675
Satapanawat Sittihan, Shingo Harada, Tomohiro Isono, Tetsuhiro Nemoto, Somsak Ruchirawat. Molecular Reconstruction with Stereochemical Relay: An Investigation into the Rearrangement of Spiro[4.5]decadienone to Benzoxepane. Chemistry - An Asian Journal. 2024. 19. 2
Shingo Harada, Shumpei Hirose, Mizuki Takamura, Maika Furutani, Yuna Hayashi, Tetsuhiro Nemoto. Silver(I)/Dirhodium(II) Catalytic Platform for Asymmetric N-H Insertion Reaction of Heteroaromatics. Journal of the American Chemical Society. 2023. 146. 1. 733-741

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MISC (11)：

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Education (2)：

The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Chemistry
The University of Tokyo Faculty of Pharmaceutical Sciences

Professional career (1)：

Work history (6)：

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Awards (12)：

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Association Membership(s) (4)：

有機合成化学協会 , 日本化学会 , 日本薬学会 , ヨウ素学会

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