Rchr

J-GLOBAL ID：200901005157145959 Update date: Jan. 30, 2024

Nawa Mikiro

ナワミキロウ | Nawa Mikiro

Affiliation and department：
Job title： graduate student
Homepage URL (1)： http://www.tokyo-med.ac.jp/pharmacol/top.html

Research field (2)： Pharmacology , Neuroscience - general

Research keywords (5)： BTBD10 , Alzheimer's Disease , Amyotrophic Lateral Sclerosis , 神経薬理学 , Neuropharmacology

Research theme for competitive and other funds (7)：

2021 - 2024 TDP-43リン酸化に着目した神経細胞死機構解明とALS/FTD治療戦略の構築
2015 - 2018 筋萎縮性側索硬化症運動神経細胞でのBTBD10発現低下と病態発症・進行との関連性
2012 - 2015 細胞死抑制因子BTBD10の発現量はなぜALS脊髄運動神経細胞で減少するのか?
2011 - 2012 ALS病態におけるBTBD10発現量低下の意義解明
2010 - Akt活性増強因子BTBD10のがん細胞における発現調節機構解明

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Papers (28)：

Shinya Kusakari, Mikiro Nawa, Yuichi Hashimoto, Masaaki Matsuoka. CLSPCOL rescues Alzheimer's disease mouse models. Translational neuroscience. 2022. 13. 1. 11-19
Yuichi Hashimoto, Shinya Kusakari, Mikiro Nawa, Koichi Okamoto, Yuka Toyama, Masaaki Matsuoka. Restoration of the reduced CLSP activity alleviates memory impairment in Alzheimer disease. Translational Psychiatry. 2021. 11. 1. 44-44
Takahara Y, Miyachi N, Nawa M, Matsuoka M. Calmodulin-like skin protein suppresses the increase in senescence-associated β-galactosidase induced by hydrogen peroxide or ultraviolet irradiation in keratinocytes. Cell biology international. 2019. 43. 7. 835-843
Shinya Kusakari, Mikiro Nawa, Katsuko Sudo, Masaaki Matsuoka. Calmodulin-like skin protein protects against spatial learning impairment in a mouse model of Alzheimer disease. Journal of Neurochemistry. 2018. 144. 2. 218-233
Yuichi Hashimoto, Yuka Toyama, Shinya Kusakari, Mikiro Nawa, Masaaki Matsuoka. An Alzheimer Disease-linked Rare Mutation Potentiates Netrin Receptor Uncoordinated-5C-induced Signaling That Merges with Amyloid beta Precursor Protein Signaling. JOURNAL OF BIOLOGICAL CHEMISTRY. 2016. 291. 23. 12282-12293

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MISC (8)：

Yuichi Hashimoto, Mikiro Nawa, Tomohiro Chiba, Sadakazu Aiso, Ikuo Nishimoto, Masaaki Matsuoka. Transforming Growth Factor beta 2 Autocrinally Mediates Neuronal Cell Death Induced by Amyloid-beta (vol 83, pg 1039, 2006). JOURNAL OF NEUROSCIENCE RESEARCH. 2015. 93. 6. 984-984
Mikiro Nawa, Masaaki Matsuoka. KCTD20, an isoform of BTBD10, is a novel Akt activator. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 199P-199P
名和幹朗, 松岡正明, 中台枝里子, 三谷昌平. 運動神経細胞における細胞死抑制因子BTBD10発現低下はALS発症の一因である. 東京医科大学雑誌. 2012. 70. 1. 101-101
Yuichi Hashimoto, Nobuyuki Tachi, Mikiro Nawa, Masaaki Matsuoka. Involvement of MOCA in neuronal cell death by familial Alzheimer's disease-linked mutants of APP and presenilins. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2011. 115. 192P-192P
Yuichi Hashimoto, Mikiro Nawa, Masaaki Matsuoka. TAG-1 inhibits neuronal cell death induced by interaction between TGFβ2 and APP. 2010. 68. 4. 456-456

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Lectures and oral presentations (19)：

Calmodulin-like skin protein suppresses hydrogen peroxide- or ultraviolet-induced increase in senescence associated beta- galactosidase in keratinocytes
(第92回日本薬理学会年会 2019)
Calmodulin-like skin proteinはアルツハイマー病モデルマウスの空間学習障害を抑制する
(第28回神経行動薬理若手研究者の集い 2019)
Calmodulin-like skin proteinはアルツハイマー病モデルマウスの空間学習障害を抑制する
(第90回日本薬理学会年会 2017)
Calmodulin-like skin protein prevents spatial learning impairment of Alzheimer’s disease model mice
(Society for Neuroscience 2016, 2016)
KCTD20, an isoform of BTBD10, is a novel Akt activator
(第87回日本薬理学会年会 2014)

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Education (3)：

2004 - 2008 Keio University
2002 - 2004 Keio University
1998 - 2002 Tokyo University of Pharmacy and Life Sciences

Professional career (1)：

博士(医学) (慶應義塾大学)

Work history (6)：

2017/03 - 現在 Tokyo Medical University
2014/04 - 2017/02 Tokyo Medical University
2011/04 - 2014/03 Tokyo Medical University
2009/04 - 2011/03 Tokyo Medical University
2008/04 - 2009/03 Keio University School of Medicine

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Committee career (1)：

- 現在日本薬理学会学術評議員

Awards (2)：

2023/03 - 東京医科大学稲垣教育賞(ベストティーチャー賞)
2013/05 - Sasa Memorial Award Reduced expression of BTBD10, an Akt activator, leads to motor neuron death.

Association Membership(s) (2)：

Society for Neuroscience , THE JAPANESE PHARMACOLOGICAL SOCIETY

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