Kameyama Toshiki

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://www.fujita-hu.ac.jp/~tkame

Research field (6)： Neuroscience - general , Tumor biology , Cell biology , Developmental biology , Molecular biology , Neuroanatomy and physiology

Research keywords (18)： Hypothalamus , knockout mouse , Neural Circuit Formation , RNA-seq , Cancer , pre-mRNA splicing , Neural Stem Cell , GFP , 共焦点顕微鏡 , NZF , Neuronal Differentiation , 増殖 , Zinc Finger , 胚性腫瘍細胞 , 転写制御因子 , 過剰発現実験 , Differntiation , 神経前駆細胞

Research theme for competitive and other funds (15)：

2022 - 2025 Induction of hypothalamic neurons by neuronal direct reporogramming
2017 - 2020 成熟mRNA再スプライシングの癌細胞生物学的悪性化に対する広範な影響の解析
2017 - 2019 Global profiling of cancer-associated exitron splicing
2014 - 2018 関節拘縮を呈するNZF-2/-3二重変異マウスを用いた神経回路形成機構の解析
2016 - 2017 成熟mRNA再スプライシングに由来する癌細胞特異的異常転写産物の網羅的探索と制御機構の解析

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Papers (28)：

Miho Kawata, Yu Kodani, Mahito Ohkuma, Ei-Ichi Miyachi, Yoko S Kaneko, Akira Nakashima, Hidetaka Suga, Toshiki Kameyama, Kanako Saito, Hiroshi Nagasaki. Long-range axonal projections of transplanted mouse embryonic stem cell-derived hypothalamic neurons into adult mouse brain. PloS one. 2022. 17. 11. e0276694
Yu Kodani, Miho Kawata, Hidetaka Suga, Takatoshi Kasai, Chikafumi Ozone, Mayu Sakakibara, Atsushi Kuwahara, Shiori Taga, Hiroshi Arima, Toshiki Kameyama, et al. EpCAM Is a Surface Marker for Enriching Anterior Pituitary Cells From Human Hypothalamic-Pituitary Organoids. Frontiers in Endocrinology. 2022. 13. 941166-941166
Yu Kodani, Miho Kawata, Hidetaka Suga, Yoko S Kaneko, Akira Nakashima, Toshiki Kameyama, Kanako Saito, Hiroshi Nagasaki. Characterization of Hypothalamic MCH Neuron Development in a 3D Differentiation System of Mouse Embryonic Stem Cells. eNeuro. 2022
Huey-Huey Chua, Toshiki Kameyama, Akila Mayeda, Te-Huei Yeh. Epstein-Barr Virus Enhances Cancer-Specific Aberrant Splicing of TSG101 Pre-mRNA. International journal of molecular sciences. 2022. 23. 5
Otani, Yuta, Fujita, Ken-ichi, Kameyama, Toshiki, Mayeda, Akila. The Exon Junction Complex Core Represses Cancer-Specific Mature mRNA Re-Splicing: A Potential Key Role in Terminating Splicing. International Journal of Molecular Sciences. 2021. 22. 12. 6519

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MISC (20)：

KAWATA Miho, KODANI Yu, KAMEYAMA Toshiki, NAKASHIMA Akira, NAGASAKI Hiroshi. Axon-guidance to the posterior pituitary on grafted hypothalamic neurons from mouse ES cells. 日本神経化学会大会抄録集(Web). 2020. 63rd
安部明弘, 山本幸也, 岡本晃直, 入山智沙子, 徳田倍将, 稲熊容子, 蟹江匡治, 冨田章裕, 赤塚美樹, 岡本昌隆, et al. ETV6の再構成による異所性遺伝子発現を認めた急性骨髄性白血病の二症例(Two cases of AML with ectopic gene expression resulting from the ETV6 rearrangements). 臨床血液. 2018. 59. 9. 1642-1642
塚本健太郎, 亀山俊樹, 山口央輝, 鈴木匡弘, 堀口安彦, 土井洋平. Bartonella henselaeによる新規内皮細胞増殖関連蛋白質の産生(Novel endothelial cell growth-related protein produced by Bartonella henselae). 日本細菌学雑誌. 2018. 73. 1. 112-112
塚本健太郎, 亀山俊樹, 山口央輝, 鈴木匡弘, 堀口安彦, 土井洋平. Bartonella henselaeによる新規内皮細胞増殖関連蛋白質の産生(Novel endothelial cell growth-related protein produced by Bartonella henselae). 日本細菌学雑誌. 2018. 73. 1. 112-112
塚本健太郎, 亀山俊樹, 山口央輝, 鈴木匡弘, 堀口安彦, 土井洋平. Novel endothelial cell growth-related protein produced by Bartonella henselae. 日本細菌学雑誌(Web). 2018. 73. 1

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Books (2)：

分子細胞生物学辞典第2版
2009
Bio Science Word Library
1996

Lectures and oral presentations (14)：

Induction of hypothamic paraventricular nucleus and supraoptic nucleus neuron by direct reprogramming
(2022)
EJCが癌特異的な成熟 mRNA再スプライシングを抑制する:mRNAの品質管理に関わる新たな EJCの役割
(【ワークショップ】真核生物におけるストレスに応答した遺伝子発現制御とその破綻に伴う老化および疾患第42回日本分子生物学会年会 2019)
EJC CORE REPRESSES CANER-SPECIFIC MATURE mRNA RE-SPLICING: EJC AS A SIGNAL TO TERMINATE SPLICING
(Cold Spring Harbor Laboratory Meeting “EUKARYOTIC mRNA PROCESSING” 2019)
Cancer specific aberrant mRNA re-splicing and its repressors: What are the splicing termination mechanisms destroyed in cancer cells?
(Invited Seminar, Department of Applied Genetics and Cell Biology (DAGZ) University of Natural Resources and Life Sciences (BOKU) 2019)
Identification of Tumor Suppressor RBM4a as a Repressor of Cancer-Specific Mature mRNA Re-splicing
(The 77th Annual Meeting of the Japanese Cancer Association 2018)

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Education (2)：

1992 - 1997 Nagoya University Graduate School of Science
1988 - 1992 Tohoku University School of Science Department of Biology

Professional career (1)：

博士(理学) (名古屋大学)

Work history (7)：

2022/04 - 現在 Fujita Health University Department of Physiology, School of Medicine Associate Professor
2016/04 - 現在 Chukyogakuin University Faculty of Nursing
2020/04 - 2022/03 Fujita Health University Department of Physiology, School of Medicine Senior Assistant Professor
2018/10 - 2020/03 Fujita Medical University Division of Gene Expression Mechanism, Institute for Comprehensive Medical Science Assistant Professor
2007 - 2018/10 藤田保健衛生大学総合医科学研究所遺伝子発現機構学研究部門助教

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Association Membership(s) (7)：

The Physiological Society of Japan , 日本RNA学会 , THE JAPANESE CANCER ASSOCIATION , 日本分子生物学会 , Society for Neuroscience , 日本神経科学会 , 日本発生生物学会

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