Rchr
J-GLOBAL ID：200901005813476304
Update date: Oct. 22, 2021
Takeshita Sunao
タケシタ スナオ | Takeshita Sunao
Affiliation and department：
Job title：
Chief, (Section of Joint Disease)
Homepage URL (1)：
http://www.ncgg.go.jp/department/bjd/bjd/index.htm
Research field (3)：
Orthopedics
, Human pathology
, Cell biology
Research keywords (6)：
細胞分化
, 骨・筋肉
, 骨・軟骨代謝学
, Cell Differentiation
, Bone/Muscle
, Bone/Cartilage Metabolic Studies
Research theme for competitive and other funds (7)：
- 2016 - 2018 骨カップリング因子Cthrc1の骨形成促進機構の解明と創薬への応用
- 2014 - 2015 破骨細胞の骨基質認識に関わる遺伝子群の網羅的機能解析
- 2010 - 2012 骨吸収特異的転写制御機構の解明
- 2005 - 2009 Study for the Regulatory Mechanisms of Bone Metabolism by Osteoclastic factors
- 2007 - 2008 破骨細胞因子による骨代謝制御機構の解明
- 2005 - 2007 高齢者の骨関節疾患の発症因子と新しい治療法に関する研究
- 2005 - 2007 Study for the Cansative Factors and the New Therapy of Aged Bone and Joint Diseases
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Papers (53)：
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Kazuhiko Matsuoka, Yukihiro Kohara, Yoshinori Naoe, Atsushi Watanabe, Masako Ito, Kyoji Ikeda, Sunao Takeshita. WAIF1 Is a Cell-Surface CTHRC1 Binding Protein Coupling Bone Resorption and Formation. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2018. 33. 8. 1500-1512
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Sunao Takeshita, Toshio Fumoto, Masako Ito, Kyoji Ikeda. Serum CTX levels and histomorphometric analysis in Src versus RANKL knockout mice. Journal of Bone and Mineral Metabolism. 2018. 36. 3. 264-273
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Lijun Wang, Caterina Iorio, Kevin Yan, Howard Yang, Sunao Takeshita, Sumin Kang, Benjamin G. Neel, Wentian Yang. A ERK/RSK-mediated negative feedback loop regulates M-CSF-evoked PI3K/AKT activation in macrophages. FASEB Journal. 2018. 32. 2. 875-887
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Takeshita S. [Coupling of bone resorption and formation.]. Clinical calcium. 2017. 27. 12. 1705-1711
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Kyoji Ikeda, Sunao Takeshita. The role of osteoclast differentiation and function in skeletal homeostasis. JOURNAL OF BIOCHEMISTRY. 2016. 159. 1. 1-8
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MISC (21)：
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K Kaji, S Takeshita, K Miyake, T Takai, A Kudo. Functional association of CD9 with the Fc gamma receptors in macrophages. JOURNAL OF IMMUNOLOGY. 2001. 166. 5. 3256-3265
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J Kawaguchi, Kii, I, Y Sugiyama, S Takeshita, A Kudo. The transition of cadherin expression in osteoblast differentiation from mesenchymal cells: Consistent expression of cadherin-11 in osteoblast lineage. JOURNAL OF BONE AND MINERAL RESEARCH. 2001. 16. 2. 260-269
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Targeted disruption of cadherin-11 leads to a reduction in bone density in calvaria and long bone metaphyses. J. Bone Mener. Res. 2001
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Identification and characterization of mouse bone marrow stroal cell lines immortalized by temperature sensitive SV40T antigen: supportive activity for osteoclast diferentiation. Bone. 2001
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S Takeshita, K Kaji, A Kudo. Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclasts. JOURNAL OF BONE AND MINERAL RESEARCH. 2000. 15. 8. 1477-1488
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Education (4)：
- - 1984 University of Miyazaki
- - 1984 University of Miyazaki Graduate School, Division of Agriculture
- - 1982 University of Miyazaki Faculty of Agriculture
- - 1982 University of Miyazaki Faculty of Agriculture
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