Yokosuka Akihito

ヨコスカアキヒト | Yokosuka Akihito

Affiliation and department：
Job title： Associate Professor

Research field (1)： Environmental and pharmaceutical development resources

Research keywords (9)： apoptosis , 細胞毒性 , サポニン , 配糖体 , 高等植物 , cytotoxic , glycosides , saponin , plants

Research theme for competitive and other funds (9)：

2021 - 2025 分子シャペロンの制御を基盤とした植物由来新規がん分子標的治療薬シーズの探索
2018 - 2021 Discovery of the seeds for novel cancer molecular-targeted agents from plant-derived steroid compounds
2017 - 2021 Search for new natural products with anticancer potential in targeting with AMPK, and their combination effects with metformin
2014 - 2018 Discovery of the seeds for plant-derived molecular-targeted agents with a focus on microtubule dynamics
2006 - 2008 Researches into phytochemicals leading to the improvement of metabolic syndrome

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Papers (102)：

海老原樹, 横須賀章人, 三宅克典, 三巻祥浩. キョウチクトウ科テイカカズラTrachelospermum asiaticum茎から単離された新規プレグナン配糖体の構造. 日本薬学会年会要旨集. 2022. 142年会. 27PO1-13S
Akihito Yokosuka, Tatsuya Shimomura, Shohei Yokogawa, Airi Oguro, Katsunori Miyake, Yoshihiro Mimaki. Chemical Components in Hedera rhombea Leaves and Their Cytotoxicity. Chemical & pharmaceutical bulletin. 2022. 70. 2. 175-181
Akihito Yokosuka, Keita Ishihara, Tsuyoshi Yamada, Tomoki Iguchi, Yoshihiro Mimaki. Steroidal Glycosides from the Aerial Parts of Avena sativa L. and Their Cytotoxic Activity. Journal of agricultural and food chemistry. 2021. 69. 48. 14568-14579
Akihito Yokosuka, Tomoki Iguchi, Maki Jitsuno, Yoshihiro Mimaki. Structure and Cytotoxicity of Novel Lignans and Lignan Glycosides from the Aerial Parts of Larrea tridentata. Molecules (Basel, Switzerland). 2021. 26. 20
Akihito Yokosuka, Misaki Honda, Hitoshi Kondo, Yoshihiro Mimaki. Chemical Constituents of the Whole Plant of Verbena hastata and Their Inhibitory Activity Against the Production of AGEs. NATURAL PRODUCT COMMUNICATIONS. 2021. 16. 4

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MISC (209)：

吉澤由佳, 猪俣美菜, 横須賀章人, 井口巴樹, 三巻祥浩. Chemical components of Ranunculaceae plants (39) Apoptosis-inducing activity of bufadienolide derivative from the whole plants of Helleborus niger. 日本薬学会年会要旨集(Web). 2023. 143rd
高橋直煕, 井口巴樹, 永峯杏樹, 横須賀章人, 三巻祥浩. ユリ科Agapanthus africanus地下部から単離された新規ステロイド配糖体の構造とSBC-3ヒト小細胞肺がん細胞に対するアポトーシス誘導活性. 日本生薬学会年会講演要旨集. 2022. 68th
平野愛実, 青木柾行, 高取和広, 小黒愛理, 松尾侑希子, 横須賀章人, 三巻祥浩. Combined effect of Japanese herbal medicine and metformin and chemical constituents from Clematis mandshurica roots and rhizomes. 日本薬学会年会要旨集(Web). 2021. 141st
大澤志拓, 大沢採香, 横須賀章人, 三巻祥浩. Sesquiterpene derivatives from Artemisiae Folium. 日本薬学会年会要旨集(Web). 2021. 141st
吉澤由佳, 猪俣美菜, 横須賀章人, 三巻祥浩. Chemical components of Ranunculaceae plants (36) Steroidal derivatives from the whole plants of Helleborus niger, and their cytotoxicity and apoptosis inducing activity. 日本薬学会年会要旨集(Web). 2021. 141st

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Education (4)：

- 1999 Tokyo University of Pharmacy and Life Sciences Graduate School of Pharmacy
- 1999 Tokyo University of Pharmacy and Life Science Graduate School, Division of Pharmaceutical Sciences
- 1997 Tokyo University of Pharmacy and Life Sciences School of Pharmacy School of Pharmacy
- 1997 Tokyo University of Pharmacy and Life Science Faculty of Pharmaceutical Science

Professional career (1)：

Awards (3)：

Association Membership(s) (4)：

MEDICAL AND PHARMACEUTICAL SOCIETY FOR WAKAN-YAKU , THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER , 日本生薬学会 , 日本薬学会

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