Tsujita Maki

• 2023 - 2026 Pathomechanism and therapeutic approach for Ritscher- Schinzel syndrome: comprehensive understanding of membrane protein recycling disorders.
• 2022 - 2025 Studies on novel HDL cholesterol efflux mechanisms
• 2020 - 2021 Effect of WAON treatment on lipoprotein metabolism: CETP tg mice study
• 2020 - 2021 Effects of the magnetic field on ABCA1-mediated cellular lipid release
• 2018 - 2019 Study in prebHDL generation; exploring the ABCA1-independent mechanism
2018 - 2019 Identification of the docking interface between ABCA1 and apoA-I that is critical for lipid loading of HDL particles
2015 - 2018 Elucidation of mechanism on neuronal cell death and development of hemodiagnosis in ischemic stroke
2015 - 2018 Explication of cholesterol efflux mechanism from small intestine
2017 - 2018 Study in prebHDL generation; exploring the ABCA1-independent mechanism
2011 - 2015 Studies of TICE and intesitinal SR-BI
2004 - 2004 脳内HDLの機能;脳コレステロール輸送と障害の修復
2003 - 2004 Elucidation of HDL generation mechanism in hepatocytes
2003 - 2003 脳内HDLの機能:脳コレステロール輸送と障害の修復
2002 - 2003 Molecular Basis of Intracellular Cholesterol Homeostasis and Genration of HDL
2001 - 2002 Explication of HDL biosynthesis: prebHDL generation from liver cells
2001 - 2001 脳内HDLの機能;脳コレステロール代謝平衡と障害の修復
2000 - 2001 脳内HDLの機能:脳ステロール代謝平衡と障害の修復
2000 - 2001 Molecular Basis of Intracellular Cholesterol Homeostasis
1998 - 1999 Homeostasis and its pathology of cellular lipid
1998 - 1999 Study in cell biology of the etiology for low HDLemia
1997 - 1998 Mechanism for cellular cholesterol remoral mediated by an apolipoprotein receptor(s)
1997 - 1998 Enhancement of cellular cholesterol efflux and atherosclerosis treatwent by pharmacological stimulation of an apolipoprotein receptor(s)
1993 - 1996 Modulation of cellular cholesterol efflux

• Maki Tsujita, John T. Melchior, Shinji Yokoyama. Lipoprotein particles in cerebrospinal fluid. Arteriosclerosis, Thrombosis, and Vascular Biology. 2024
• Mark Castleberry, Chase A Raby, Anca Ifrim, Yasuhiro Shibata, Sachi Matsushita, Shinya Ugawa, Yutaka Miura, Atsushi Hori, Takashi Miida, MacRae F Linton, et al. High-density lipoproteins mediate small RNA intercellular communication between dendritic cells and macrophages. Journal of lipid research. 2023. 64. 2. 100328-100328
• Shiomi Otsuji, Yosuke Nishio, Maki Tsujita, Marlene Rio, Céline Huber Lequesne, Valérie Cormier-Daire, Carlos Antón-Plágaro, Seiji Mizuno, Yoshihiko Kawano, Satoko Miyatake, et al. Clinical diversity and molecular mechanism of VPS35L-associated Ritscher-Schinzel syndrome. Journal of Medical Genetics. 2022. 60. 4. 359-367
• Maki Tsujita, Sachi Matsushita, Hiroshi Takase. Modulation of lipoprotein profiles by the WAON treatment in mice. Japanese Journal of Health and Research. 2021. 42. 42. 69-76
• Maki Tsujita, Boris Vaisman, Liu Chengyu, Kasey C. Vickers, Kei-ichiro Okuhira, Sten Braesch-Andersen, Alan T. Remaley. Apolipoprotein A-I in mouse cerebrospinal fluid derives from the liver and intestine via plasma high-density lipoproteins assembled by ABCA1 and LCAT. FEBS letters. 2020

ｍore...

• 辻田 麻紀, 高瀬 弘嗣, 熊本 奈都子, 鵜川 眞也, 古家 圭人, 鍔木 基成. マウスにおけるABCA1を介した細胞コレステロール搬出および成体脳細胞新生に対する磁場の影響. 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [P-150]
• 辻田 麻紀, 松下 佐知, 中須賀 公亮, 高瀬 弘嗣. 和温療法によるマウス血中リポタンパク質代謝平衡の改変. 日本動脈硬化学会総会プログラム・抄録集. 2021. 53回. 243-243
• 末永 翔平, 金山 忠史, 橘 茉里奈, 楠本 嵩志, 杉原 涼, 西辻 和親, 辻田 麻紀, 石田 竜弘, 奥平 桂一郎. apoA-I結合タンパク質AIBPの抗炎症活性発現メカニズムの検討. 日本薬学会年会要旨集. 2019. 139年会. 3. 66-66
• 橘 茉里奈, 末永 翔平, 楠本 嵩志, 杉原 涼, 高田 春風, 西辻 和親, 辻田 麻紀, 石田 竜弘, 奥平 桂一郎. 炎症モデルマウスにおけるapoA-I結合タンパク質AIBPの抗炎症作用の検討. 日本薬学会年会要旨集. 2019. 139年会. 3. 66-66
• Maki Tsujita, Shinya Ugawa, Shinji Yokoyama. Short Term Taste Preference for Cholesterol Rich Diet in ABCA1 Null Mice. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2017. 37

ｍore...

• Research on novel HDL cholesterol excretion mechanism
  Science Impact Ltd 2023
• Molecular Basis of Cellular Cholesterol Efflux and Regulation of Plasma HDL level
  Springer 2000
• Molecular Basis for cellular cholesterol efflux and regulation of plasma HDL levels.
  Elsevier Secience B.V 1999
• An essential amino acid sequence of the substrate (amine)-binding region of porcine FAD-containing monooxygenase.
  University of Calgary Press 1996
• Cholesterol-binding region of cytochrome P450scc(P450XIA1): identification and amino acid sequence of the cholesterol binding domain.
  John Libbey Eurotext 1994

ｍore...

• Dyslipidemia and sudden cardiac death
  (UCSF Cardiac Electrophysiology research conference 2024)
• Apolipoprotein A-I in the brain
  (HDL workshop 2024 2024)
• Lipoprotein characteristics in VPS35L-associated Ritscher-Schinzel syndrome
  (Brigham and Women’s Hospital Genetics Division Seminar, Harvard New Research Building (NRB), room 457 2023)
• Apolipoprotein A-I origin and the function of ABCA1 in mouse adult-neurogenesis at the hippocampal dentate gyrus
  (Medical University Vienna, Center for Physiology and Pharmacology, Institute of Pharmacology, Waehringerstrasse 13a, 1090 Vienna, "Gr. HS Pharmakologie" 2023)
• Magnetic field-treated mice reduce adult-neurogenesis at the hippocampal dentate gyrus: implication of the PPARa pathway
  (Special seminar (virtual), Building 37 Room 3106, NCI, NIH, Bethesda, MD, USA 2022)

ｍore...

• - 1993 Kagawa Medical School Graduate School of Medicine Biochemistry
• - 1989 University of Kobe Graduate School of Science Biology
• - 1987 Konan University Faculty of Science Biology

• Doctor of Philosophy in Medical Science (Kagawa Medical School)
• Doctor of Philosophy in Science (Konan University)

• 2019 - 現在 Associate Professor, Biochemistry, Nagoya City University Graduate School of Medical Sciences
• 2008 - 2019 Associate Professor, Biochemistry, Nagoya City University Graduate School of Medical Sciences
• 1996 - 2008 Assistant Professor, Biochemistry 1, Nagoya City University Medical School (Nagoya, Japan)
• 1993 - 1996 Postdoctoral fellow, Lipid and Lipoprotein Research Group, University of Alberta, Canada.
• 1993 - 1996 Assistant Professor, Biochemistry, Kagawa Medical School

• 2023/03 - 現在 The ABC transporter FEBS Special Meeting Organizer
• 2022/11 - 現在 The Japanese Biochemical Society Council member
• 2018/07 - 現在 Japan Atheroscleosis Society International comittee member, Council member
• 2018/03 - 現在 ABC2020-8th FEBS Special Meeting ABC2020 Scientific Advisory Board
• 2024/04 - 2026/03 Japanese Circulation Society Delegate member

• 2021/09 - The American Heart Association Paul Dudley White International Scholar Award
• 2019/10 - Nagoya City University International Collaboration Journals Award
• 2019/05 - the American Heart Association International Fellow, conferred by ATVB
• 1999/12 - Nagoya City University Medical Research Award

Japan Society for Dementia Research ,  Japan Transporter Research Association ,  P450_UGT_SULT ,  European Atherosclerosis Society ,  American Heart Association, ATVB (International Fellow of AHA) ,  The Japanese Circulation Society, Delegate (R6-R7) ,  Japan Atherosclerosis Society(International committee member, and Council member) ,  The Japanese Biochemical Society (Counsil member) ,  The Japanese Society for Neurochemistry