Rchr

J-GLOBAL ID：200901006607634200 Update date: Apr. 25, 2024

Ashihara Takashi

アシハラタカシ | Ashihara Takashi

Affiliation and department：
Job title： Assistant Professors
Homepage URL (1)： http://square.umin.ac.jp/ash/arrhythmia.html

Research field (10)： Internal medicine - General , Biological, health, and medical informatics , Information networks , Computer systems , Medical systems , Biomaterials , Biomedical engineering , Clinical pharmacy , Physiology , Cardiology

Research keywords (4)：コンピュータシミュレーション , 医用生体工学 , 不整脈 , 循環器内科

Research theme for competitive and other funds (32)：

2023 - 2026 A translational research to elucidate the mechanism of rotor control based on real-time imaging of refractory atrial fibrillation.
2021 - 2024 Development of mature iPSC cardiomyocytes toward drug development
2021 - 2023 位相分散解析と不整脈の臨床的可視化手法の統合による慢性心房細動の多元的治療戦略
2021 - 2023 位相シンギュラリティに基づく心房細動のダイナミクス変容とロバスト性に関する研究
2020 - 2022 Development of a new ablation strategy based on the real-time imaging and analysis of non-paroxysmal atrial fibrillation

2020 - 2022 多階層3次元心臓モデルを用いた不整脈誘発性・持続性の評価に関するインシリコ研究

2020 - 2022 WPW症候群の顕在化メカニズム解明に向けたシミュレーション研究

2019 - 2022 ヒトiPS細胞を用いた新世代統合的評価法による薬物誘発性不整脈の病態解析

2016 - 2019 The elucidation of mechanisms underlying triggered activity in inheritable lethal arrhythmias: in silico predictions

2016 - 2019 Clinical and in silico fusion studies for producing innovations in chronic atrial fibrillation ablation

2016 - 2019 Arrhythmic origin identification by a four-dimensional constructive method using virtual heart simulation and vector electrocardiogram

2016 - 2019 Simulation study of investigating mechanisms of ventricular rate in atrioventricular node using 3-dimensional atrioventricular node model

2016 - 2019 A new technology for tissue diagnosis with combination of Raman scattering spectrometry and bioimpedance measurement

2015 - 2019 Multidisciplinary approach to cardiac arrhythmogenesis assessment during drug discovery

2015 - 2018 Elucidation of Mechanism of Ventricular Fibrillation and Development of Markers in Predicting Sudden Cardiac Death by Medical-Engineering Cooperation

2015 - 2018 Termination mechanisms of atrial fibrillation by rotor-based ablation and establishment of patient-tailored atrial fibrillation therapy

2015 - 2018 Multilateral Research on the Mechanisms of Inherited Arrhythmias

2015 - 2018 Novel ablative approaches based on computational science for atrial fibrillation driver

2013 - 2017 遺伝性不整脈に対するカテーテルアブレーション治療法の開発

2013 - 2016 Theoretical studies on ablation targets and optimal approach of chronic atrial fibrillation treatment.

2012 - 2015 Roles of subcellular sodium channel redistribution in the generation of lethal arrhythmia: in silico study

2012 - 2015 Investigating mechanisms of ventricular arrhythmias induced in the Purkinje fiber network using computer simulation

2012 - 2015 Development of Electrophysiological Indices in Predicting Sudden Cardiac Death through medicine-engineering collaboration

2012 - 2015 Reconstruction of three dimensional excitation propagation waveform in heart wall from two dimensional optical mapping data

2010 - 2015 Integrative simulation of electrophysiological activities in the heart reflecting multi-level data

2011 - 2014 Multidisciplinary Studies on Molecular Pathogenesis of Inherited Primary Arrhythmia Syndromes

2009 - 2012 In silico study of mechanism and therapy of chronic atrial fibrillation based on the human atrial numerical model

2009 - 2011 Evaluation of Efficacy and Long-term Results of Catheter Ablation in Drug-refractory Atrial Fibrillation

2009 - 2011 Development of functional modeling techniques for predicting arrhythmic risk in virtual heart simulation

2007 - 2009 New strategies for treatment and prevention of life-threatening ventricular tachyarrhythmias by unpinning of spiral-wave reentry

2006 - 2008 Study for the modeling tools to compose a virtual heart electrophysiological simulator and for designing modularized software with the aim of integrated human body simulation

2005 - 2006 ヒト心室筋モデルの構築を基盤とした致死性不整脈発生の予知に関する理論的研究

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Papers (357)：

Yusuke Okuyama, Tomoya Ozawa, Takuma Nishikawa, Yusuke Fujii, Koichi Kato, Yoshihisa Sugimoto, Yoshihisa Nakagawa, Takashi Ashihara. Association with the nonparoxysmal atrial fibrillation duration and outcome of ExTRa Mapping-guided rotor ablation. Journal of Arrhythmia. 2023. 39. 4. 531-538
Tadafumi Nanbu, Akihiko Yotsukura, George Suzuki, Hiroyuki Takekawa, Yuki Tanaka, Katsuma Yamanashi, Masaya Tsuda, Izumi Yoshida, Masayuki Sakurai, Takashi Ashihara. Organization of atrial fibrillation using a pure sodium channel blocker: Implications of rotor ablation therapy. Journal of Arrhythmia. 2023. 39. 3. 327-340
Asuka Nishimura, Masahide Harada, Takashi Ashihara, Yoshihiro Nomura, Yuji Motoike, Masayuki Koshikawa, Takehiro Ito, Eiichi Watanabe, Yukio Ozaki, Hideo Izawa. Effect of pulmonary vein isolation on rotor/multiple wavelet dynamics in persistent atrial fibrillation, association with vagal response and implications for adjunctive ablation. Heart and Vessels. 2023. 38. 5. 699-710
Kadota Yosuke, Morino Katsutaro, Motoyama Kazutaka, Shigetoshi Kenji, Fukue Kei, Ishii Mariko, Ashihara Takashi. Impact of Remote and Face-to-face Lecture on the Grade Point Average Using Telecommunication Big Data. Journal for Academic Computing and Networking. 2022. 26. 1. 79-86
Tetsuo Ono, Kodai Hino, Tomoko Kimura, Yasuhiro Uchimura, Takashi Ashihara, Takako Higa, Hideto Kojima, Takashi Murakami, Jun Udagawa. Excessive folic acid intake combined with undernutrition during gestation alters offspring behavior and brain monoamine profiles. Congenital anomalies. 2022. 62. 4. 169-180

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MISC (328)：

How do cardiovascular implantable electronic devices perform electrical pacing or defibrillation?. Heart View. 2024. 28. 1. 27-32
坂田憲祐, 芦原貴司. 最先端医療の今臨床不整脈映像化システムによる最適な非発作性心房細動治療戦略の確立. Medical Science Digest. 2023. 49. 12. 678-680
Takashi Ashihara, M.D., Ph.D. Medical-engineering collaboration in the development of a clinical arrhythmia imaging system. 2023. 287. 1. 58-66
芦原貴司. 「ちょっとぼーっと」した疲れた頭を解きほぐす!ChatBotの話. 心電図. 2023. 43. 2. 87-88
中澤純, 廣坂雄介, 吉田尚平, 佐々木裕二, 高谷季穂, 荒牧陽, 大橋誠治, 川人浩之, 西山順博, 山田衆, et al. 長期間の腎機能推移(Long-term eGFR plot)に立脚した潜在的腎予後不良症例の実態調査. 日本腎臓学会誌. 2023. 65. 3. 276-276

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Patents (10)：

表示制御装置および表示制御装置の作動方法
心筋興奮補完・可視化装置及び心筋興奮検出装置.
心筋興奮判別装置
心筋興奮補完・可視化装置及び心筋興奮検出装置
心筋興奮補完・可視化装置

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Books (39)：

Handbook for Medical Engineering
2022 ISBN:9784860437350
スマート医療テクノロジー
エヌ・ティー・エス 2019 ISBN:9784860436193
上級医の循環器治療手技:カテーテルアブレーション
2019 ISBN:9784784962709
心電図検定公式問題集&ガイド:受験者必携! 2級/3級改訂3版
メディカ出版 2018
線維芽細胞と興奮伝導・伝播異常
メディカルレビュー社 2017

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Lectures and oral presentations (991)：

心電図判読力アップのために.心電図検定対策講座(2~3級向け):心電図検定に向けて、心電図の判読力を上げよう!
(第2回日本不整脈心電学会近畿支部地方会 2022)
不整脈の可視化:心房細動をリアルタイムで映像化する医療機器.
(森ノ宮医療大学系統講義:先進科学技術論. 2022)
Exponential Mapを用いた3次元心房モデル上の興奮伝播可視化.
(Visual Computing + VC Communications 2022 (VC+VCC 2022). 2022)
除細動に関する基礎的事項:電気的除細動の効率化に必要なことは何か:理論的研究に基づく洞察.
(第55回ペーシング治療研究会 2022)
非発作性心房細動の術中リアルタイム映像化にかかる解析的手法の開発と改良:人工知能の応用を含めて.
(東京大学臨床生命医工学連携研究機構寄付研究部門「次世代臨床医用計測技術研究ネットワーク拠点」第3回シンポジウム. 2022)

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Education (4)：

- 2002 Shiga University of Medical Science
- 2002 Shiga University of Medical Science Graduate School, Division of Medical Sciences
- 1996 Shiga University of Medical Science Undergraduate School of Medicine Faculty of Medicine
- 1996 Shiga University of Medical Science Faculty of Medicine

Professional career (1)：

博士(医学) (滋賀医科大学)

Work history (20)：

2019/06 - 現在 Shiga University of Medical Science Multi Media Center Director
2019/06 - 現在 Shiga University of Medical Science Management Department of Medical Informatics
2019/06 - 現在 Shiga University of Medical Science Center for Information Technology Professor
2018/04 - 2019/05 Shiga University of Medical Science
2018/04 - 2019/05 Shiga University of Medical Science Multi Media Center Deputy Director

2017/08 - 2019/05 Shiga University of Medical Science

2017/04 - 2019/05 Shiga University of Medical Science Medical Director of Education of Cardiovascular Medicine

2016/04 - 2019/05 Shiga University of Medical Science Associate Professor, Department of Medical Informatics and Biomedical Engineering

2012 - 2017/07 Shiga University of Medical Science Associate Professor, Department of Cardiovascular and Respiratory Medicine

2015/03 - 2017/01 Shiga University of Medical Science Medical Director of Cardiovascular Medicine Ward,

2005 - 2016 National Cardiovascular Center Research Institute Visiting Researcher

2011/02 - 2015/02 Shiga University of Medical Science Medical Director of Outpatient Clinic of Cardiovascular and Respiratory Medicine,

2007 - 2012 Shiga University of Medical Science Heart Rhythm Center, Assistant Professor, Department of Cardiovascular Medicine,

2005 - 2007 Shiga University of Medical Science Heart Rhythm Center, Assistant Professor,

2004 - 2005 Tulane University Department of Biomedical Engineering, Adjunct Professor,

2004 - 2005 Kyoto University Graduate School of Medicine Department of Physiology and Biophysics, Assistant Professor (Researcher),

2002 - Tulane University (New Orleans, LA, U.S.A.) Computational Cardiac Electrophysiology Laboratory, Department of Biomedical Engineering, Postdoctoral Research Fellow,

2002 - Shiga University of Medical Science Department of Cardiovascular and Respiratory Medicine, Attending Staff,

1998 - at National Cardiovascular Center Research Institute Externship

1996 - Trainee Doctor in Shiga University of Medical Science passed the National Exam for Medical Practitioners

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Committee career (24)：

2016/08 - 現在日本不整脈心電学会(JHRS) 心電図検定委員会委員
2016 - 現在日本生体医工学会代議員
2016 - 現在日本不整脈心電学会(JHRS) 不整脈専門医資格認定試験問題作成医員
2016 - 現在日本不整脈心電学会(JHRS) 学会誌「心電図」編集委員、最優秀論文賞選考委員
2016 - 現在日本生体医工学会論文賞・阪本賞選定委員会委員

2016 - 現在日本生体医工学会荻野賞選定委員会・委員

2016 - 現在日本不整脈心電学会(JHRS) 健康保険委員会・委員

2014/09 - 現在日本不整脈心電学会(JHRS) 日本心電学会誌「心電図」編集委員会・委員

2014 - 現在医薬品医療機器総合機構(PMDA)後援事業心臓安全性に関するシンクタンクミーティング・Computational (In silico) Safety Pharmacology WG・委員

- 現在日本不整脈心電学会(JHRS) 学術大会プログラム委員会委員

- 現在日本不整脈心電学会(JHRS) 植込みデバイス委員会社会問題対策部会部会員

- 現在日本不整脈心電学会(JHRS) 評議員

2013/10 - 2016/08 日本不整脈心電学会(JHRS) 心電図検定ワーキンググループ・委員

2015/10 - 2016 平成27年度日本生体医工学会論文賞・阪本賞選定委員会委員

2015/02 - 2015/03 経済産業省:医療機器等の開発・実用化促進のためのガイドライン策定事業ナビゲーション医療分野PDT機器開発WG・委員

2013/09 - 2015/03 厚生労働省・経済産業省連携事業次世代医療機器評価指標作成事業・心臓カテーテルアブレーション審査WG・委員

2014/01 - 2015 日本コンピュータ外科学会(JSCAS) 将来構想委員会・委員

2011/09 - 2014/08 日本心電学会(JSE) 技術・機器精度委員会・委員

2012/10 - 2013/10 第6回アジア太平洋不整脈学会(APHRS2013) 組織委員

2011/10 - 2012/10 第5回アジア太平洋不整脈学会(APHRS2012) 組織委員

2010/06 - 2011/09 第4回アジア太平洋不整脈学会(APHRS2011) 組織委員

2009/11 - 2010/12 日本心電学会(JSE) 日本不整脈学会(JHRS)統合WG・委員

2008/01 - 2010/12 日本心電学会(JSE) 将来構想委員会・委員

2006 - 2008 Japanese Society of Electrocardiology Boardman

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Awards (23)：

2019/06 - 医療情報学連合大会 2018年学術奨励賞(優秀口演賞) 心内心電図処理に基づく心房細動のリアルタイム可視化がもたらすカテーテルアブレーションの変革.
2018/09 - 生体医工学シンポジウム2018 生体医工学シンポジウムベストレビューワーアワード
2017/06 - Japanese Society for Computerized Electrocardiology (2017). Winner of the Best Abstract Award
2013/10 - The 30th Annual Meeting of the Japanese Society of Electrocardiology (JSE 2013) Winner of the Suzuken Memorial Foundation Award, The Japanese Society of Electrocardiology (2013) The role of fibroblasts in complex fractionated electrograms during persistent/permanent atrial fibrillation: Implications for electrogram-based catheter ablation.
2012/10 - DIGITAL CONTENT EXPO 2012 Winner of Innovative Technologies Special Award

2012/05 - Japanese Society for Medical and Biological Engineering Winner of the Ogino Award

2010/10 - Asia Pacific Heart Rhythm Society Clinical, The 3rd Asia-Pacific Heart Rhythm Society Scientific Session (APHRS). Roles of fibroblasts in the mechanisms of complex fractionated atrial electrograms and catheter ablation during chronic atrial fibrillation.

2009/07 - The 24th Annual Meeting of the Japanese Heart Rhythm Society (JHRS). The 26th Annual Meeting of the Japanese Society of Electrocardiology (JSE). Winner of the Young Investigator Award Tunnel propagation of postshock activations as a hypothesis for fibrillation induction and isoelectric window.

2009/07 - 2009 Winner of the Young Investigator Award, The Japanese Society of Electrocardiology.

2004/06 - The 31st International Congress on Electrocardiology (ICE) Finalist of the YIA Mechanisms of shock-induced arrhythmogenesis: Role of tissue discontinuity and electroporation in the initiation of focal repetitive postshock activations.

2004/06 - The 31st International Congress on Electrocardiology, Young Investigator's Award Finalist

2003/10 - Good Design Award of the Japan Good Design Award of the Japan Industrial Design Promotion Organization

2003/09 - 第20回日本心電学会学術集会第8回日本心電学会学術奨励賞 Widening of the excitable gap and enlargement of the core of reentry during atrial fibrillation with a pure sodium channel blocker in canine atria.

2001/11 - International Workshop on Chronoastrobiology and Chronotherapy Winner of the Halberg Prize

2001/11 - Grand Award (Halberg Prize) of the International Symposium: Workshop on Chronoastrobiology and Chronotherapy

2001/09 - Nikkei Science Visual Science Festa. Grand Award

2001/09 - Grand Award of the Nikkei Science (Japanese version of Scientific American) Visual Science Festa

1999/10 - 第13回日本エム・イー学会秋季大会. The 13th Autumn Conference of Japanese Society for Medical and Biological Engineering (JSMBE). Winner of the YIA The mechanisms of spontaneous wave breakup of spiral reentry in ventricular fibrillation: A simulation study.

1999/10 - Young Investigators Award (First Prize) of the Japanese Society for Medical and Biological Engineering

1999/06 - Nikkei Science (Japanese version of Scientific American) Computer Visualization Symposium Winner of the AVS Prize

1999/06 - Grand Award (AVS Prize) of the Nikkei Science (Japanese version of Scientific American) Computer Visualization Symposium

1999/04 - the 24th International Society Young Investigators Award Finalist Dynamics of the filaments of vortexlike reentry in three dimensional computer models.

1999/04 - Young Investigators Award Finalist of the 24th International Society for Computerized Electrocardiology

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Association Membership(s) (22)：

JSCAS , JAPAN ASSOCIATION FOR MEDICAL INFORMATICS , The Japanese College of Cardiology (JCC) , Asia Pacific Heart Rhythm Society (APHRS) , HRS , The Physiological Society of Japan (PSJ) , Japanese Society for Medical and Biological Engineering (JSMBE) , JAPANESE HEART RHYTHM SOCIETY , Japanese Circulation Society (JCS) , Japanese Society of Internal Medicine (JSIM) , The Japanese College of Cardiology , Asia Pacific Heart Rhythm Society , Heart Rhythm Society , Japanese Society for Bioinformatics , The Physiological Society of Japan , Japanese Society for Medical and Biological Engineering , Japanese Society of Electrocardiology , Japanese Circulation Society , Japanese Society of Internal Medicine , JSAI , ESC , JTTA

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