Hiroeki Sahara

サハラヒロエキ | Hiroeki Sahara

Affiliation and department：

Research field (1)： Tumor biology

Research keywords (2)：癌 , Immunology, Cancer

Research theme for competitive and other funds (19)：

2018 - 2021 Elucidation of the role of CD44 variant molecule in radiation resistance ability in canine cancer stem cells
2012 - 2013 RNAヘリカーゼによる癌化形質発現の解析
2011 - 2012 ウイルスによる発癌機構の解析
2010 - 2011 ウィルスによる発癌機構の解析
2009 - 2010 イヌ癌の放射線治療における新規放射線増感剤、TSC-0321の治療試験

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Papers (75)：

Atsushi Tanabe, Takatoshi Nakayama, Jo Kashiyanagi, Hitoshi Yamaga, Yoshihiko Hirohashi, Toshihiko Torigoe, Fukino Satomi, Hiroaki Shima, Hideki Maeda, Goro Kutomi, et al. YTHDC2 Promotes Malignant Phenotypes of Breast Cancer Cells. Journal of Oncology. 2022. 2022. 1-11
Atsushi Tanabe, Kento Kimura, Hana Tazawa, Takuya Maruo, Masayuki Taguchi, Hiroeki Sahara. Functional analysis of CD44 variants and xCT in canine tumours. Veterinary Medicine and Science. 2021. 7. 2. 577-585
Hirofumi Kawakubo, Shinji Kamisuki, Kei Suzuki, Jesus Izaguirre-Carbonell, Shiki Saito, Hiroshi Murata, Atsushi Tanabe, Ayumi Hongo, Hironobu Murakami, Sachihiro Matsunaga, et al. SQAP, an acyl sulfoquinovosyl derivative, suppresses expression of histone deacetylase and induces cell death of cancer cells under hypoxic conditions. Bioscience, Biotechnology, and Biochemistry. 2021. 85. 1. 85-91
Atsushi Tanabe, Hiroeki Sahara. The Metabolic Heterogeneity and Flexibility of Cancer Stem Cells. Cancers. 2020. 12. 10. 2780-2802
Atsushi Tanabe, Risa Shimizu, Yui Osawa, Machi Suzuki, Saki Ito, Mutsuo Goto, Luis A. Pastene, Yoshihiro Fujise, Hiroeki Sahara. Age estimation by DNA methylation in the Antarctic minke whale. Fisheries Science. 2020. 86. 1. 35-41

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MISC (13)：

佐原弘益. オートファジーによる内在性抗原のMHC class IIによる提示. 臨床免疫・アレルギー科 (科学評論社). 2007. 137-142
β-SQAG9, sulfo-glycolipid possesses a binding activity to L-selectin, and prevents neutrophil infiltration in a rat hepatic ischemia reperfusion injury model. Journal of Japan Surgical Society. 2006. 107. 2. 631-631
H Shima, T Tsuruma, H Sahara, M Takenouchi, N Takahashi, Y Iwayama, A Yagihashi, N Watanabe, N Sato, K Hirata. Treatment with beta-SQAG9 prevents rat hepatic ischemia-reperfusion injury. TRANSPLANTATION PROCEEDINGS. 2005. 37. 1. 417-421
佐原弘益. 内在性抗原のMHC class IIによる提示機構. 臨床免疫 (科学評論社). 2004. 448-454
佐原弘益. ヒトがん免疫治療の現在と未来. 北海道医誌. 2003. 7-9

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Patents (9)：

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Books (3)：

Lectures and oral presentations (44)：

YTHDC2 promotes malignant transformation of breast tumor cells by regulating c-myb.
(79th Annual Meeting of the Japanese Cancer Association 2020)
Mutant p53 suppresses the metabolic efficiency of xylitol.
(79th Annual Meeting of the Japanese Cancer Association 2020)
The effect of Wint3a on CSC-like properties of colorectal tumor cells.
(78th Annual Meeting of the Japanese Cancer Association 2019)
The role of RNA helicase YTHDC2 in marignant transformation of breast tumor cells.
(78th Annual Meeting of the Japanese Cancer Association 2019)
Functional analysis of CD44 variants and xCT in canine cancer cells.
(77th Annual Meeting of the Japanese Cancer Association 2018)

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Education (2)：

Work history (6)：

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Awards (1)：

Association Membership(s) (4)：

臨床ストレス応答学会 , 日本分子生物学会 , 日本免疫学会 , 日本癌学会

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