Job title:
Associate Professor
Research theme for competitive and other funds (22):
2022 - 2025 Elucidation of the Mechanism of Regenerative Insufficiency in Advanced Liver Cirrhosis Caused by Intestinal Bacterial Extracellular Vesicles and Development of Prevention and Treatment Methods
2020 - 2023 The mechanism in transportation and inflammation of virulent factor which is carried by extracellular vesicles
2018 - 2020 細菌とマクロファージの拡散的細胞外小胞による炎症反応の機序解明
2017 - 2020 Enhancement effect by bone marrow cell transplantation and macrophage regulation by S-allyl glutathione in rat liver fibrosis
2013 - 2015 Bile acid profiles in cholangiocarcinoma developing in printing workers for the application to early diagnosis
2012 - 2015 Analysis of anti-tubercular activity through immune activation by polyphenol and consideration of its effectiveness to the prevention and the treatment
2012 - 2014 マクロファージによる結核菌の休眠への機構の解明
2012 - 2013 潜在性結核のバイオマーカー探索と診断法への応用
2012 - 2013 ケニア国の小学生を対象とした結核菌抗原応答の解析
2010 - 2011 ケニア国における結核菌感染者の休眠期結核菌抗原に対する抗体応答の検出
2009 - 2011 低酸素下での結核菌感染マクロファージにおけるHIF-1alphaの機能解明
2009 - 2010 潜在性結核対策を想定した、抗酸菌の長期生存を可能にする分子メカニズムの解明
2007 - 2009 低酸素で誘導されるマクロファージへの分化と活性化
2004 - 2006 低酸素状態における遺伝子誘導に働くNADPH-P450還元酵素の役割
2002 - 2003 細胞の酸素濃度感知機構の解明
低酸素応答における病態の進展機構
Show all
Papers (57):
Imamiya R, Shinohara A, Yakura D, Yamaguhci T, Ueda K, Oguro A, Minamiyama Y, Ichikawa H, Horiguchi Y, Osada-Oka M. Escherichia coli-derived outer membrane vesicles relay inflammatory responses to macrophage-derived exosomes. mBio. 2023. 14. 1. e0305122
Yukihiro Hiramatsu, Takashi Nishida, Dendi Krisna Nugraha, Mayuko Osada-Oka, Daisuke Nakane, Katsumi Imada, Yasuhiko Horiguchi. Interference of flagellar rotation up-regulates the expression of small RNA contributing to Bordetella pertussis infection. Science advances. 2022. 8. 51. eade8971
Mayuko Osada-Oka, Hikaru Kuwamura, Risa Imamiya, Keiko Kobayashi, Yukiko Minamiyama, Katsuyuki Takahashi, Masako Tanaka, Masayuki Shiota. Suppression of the doxorubicin response by hypoxia-inducible factor-1α is strictly dependent on oxygen concentrations under hypoxic conditions. European journal of pharmacology. 2022. 920. 174845-174845
Mikayo Hayashi, Akihito Nishiyama, Ryuki Kitamoto, Yoshitaka Tateishi, Mayuko Osada-Oka, Yukiko Nishiuchi, Shaban A. Kaboso, Xiuhao Chen, Mamoru Fujiwara, Yusuke Inoue, et al. Adduct Formation of Delamanid with NAD in Mycobacteria. Antimicrobial Agents and Chemotherapy. 2020. 64. 5
Mikayo Hayashi, Akihito Nishiyama, Ryuki Kitamoto, Yoshitaka Tateishi, Mayuko Osada-Oka, Yukiko Nishiuchi, Shaban A. Kaboso, Xiuhao Chen, Mamoru Fujiwara, Yusuke Inoue, et al. Adduct Formation of Delamanid with NAD in Mycobacteria. Antimicrobial Agents and Chemotherapy. 2020. 64. 5
日本薬理学会
, 日本分子生物学会
, 日本生化学会
, SOCIETY FOR FREE RADICAL RESEARCH JAPAN
, the American Society for Microbiology
, JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE
, JAPANESE SOCIETY FOR BACTERIOLOGY