Momose Isao

モモセイサオ | Momose Isao

Affiliation and department：
Job title： Chief Researcher
Homepage URL (1)： http://www.bikaken.or.jp/

Research field (3)： Pharmaceuticals - health and biochemistry , Environmental and pharmaceutical development resources , Chemical biology

Research keywords (4)：天然物化学 , 応用微生物学・応用生物化学 , Natural Product Chemistry , Drug Development

Research theme for competitive and other funds (10)：

2022 - 2025 細胞膜リン脂質リモデリングを標的とした新規抗がん剤の創出
2020 - 2023 Development of comprehensive cancer immunotherapy using metabolism inhibitors
2019 - 2022 乳がんにおけるc-Mycと合成致死作用を示す新たな抗がん剤の創出
2015 - 2018 Elucidation of androgen-dependent growth inhibition mechanism in prostate cancer of novel small molecule compound APA
2014 - 2018 がん特異的代謝機構に基づいた抗腫瘍薬の開発と応用

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Papers (44)：

Yuji Kubota, Yuko Fujioka, Ashwini Patil, Yusuke Takagi, Daisuke Matsubara, Masatomi Iijima, Isao Momose, Ryosuke Naka, Kenta Nakai, Nobuo N. Noda, et al. Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer. Nature Communications. 2022. 13. 1
Isao Momose, Takefumi Onodera, Manabu Kawada. [Potential Anticancer Activity of Auranofin]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2021. 141. 3. 315-321
Takefumi Onodera, Isao Momose, Hayamitsu Adachi, Yohko Yamazaki, Ryuichi Sawa, Shun-ichi Ohba, Manabu Kawada. Human pancreatic cancer cells under nutrient deprivation are vulnerable to redox system inhibition. JOURNAL OF BIOLOGICAL CHEMISTRY. 2020. 295. 49. 16678-16690
Momose I, Onodera T, Doi H, Adachi H, Iijima M, Yamazaki Y, Sawa R, Kubota Y, Igarashi M, Kawada M. Leucinostatin Y: A Peptaibiotic Produced by the Entomoparasitic Fungus Purpureocillium lilacinum 40-H-28. Journal of natural products. 2019. 82. 5. 1120-1127
Onodera T, Momose I, Kawada M. Potential Anticancer Activity of Auranofin. Chemical & pharmaceutical bulletin. 2019. 67. 3. 186-191

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Professional career (1)：

Work history (2)：

Committee career (2)：

Association Membership(s) (4)：

THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER , 日本癌学会 , 日本放線菌学会 , 日本農芸化学会

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