Rchr

J-GLOBAL ID：200901007115758309 Update date: Jul. 08, 2022

Okamoto Hiroshi

オカモトヒロシ | Okamoto Hiroshi

Affiliation and department：
Job title： Professor Emeritus
Homepage URL (2)： http://db.tohoku.ac.jp/whois/detail/f3431c410316984fa67d7813d3feba70.html , http://db.tohoku.ac.jp/whois/e_detail/f3431c410316984fa67d7813d3feba70.html

Research field (2)： Pathobiochemistry , Medical biochemistry

Research keywords (7)： insulin secretion , cyclic ADP-ribose , Okamoto model , beta-cell death , Reg gene , dibates , Regeneration

Papers (179)：

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MISC (19)：

Okamoto H, Takasawa S. Recent advances in physiological and pathological significance of NAD(+) metabolites: roles of poly(ADP-ribose) and cyclic ADP-ribose in insulin secretion and diabetogenesis. (Nutrition Research Reviews). Nutrition Research Reviews. 2003. 16. 2. 253-266
Okamoto Hiroshi. Recent advances in physiological and pathological significance of tryptophan-NAD+ metabolites: lessons from insulin-producing pancreatic beta-cells. (Adv Exp Med Biol). Adv Exp Med Biol. 2003. 527. 243-252
Okamoto Hiroshi, Takasawa Shin. Recent advances in the Okamoto model: the CD38-cyclic ADP-ribose signal system and the regenerating gene protein (Reg)-Reg receptor system in beta-cells. (Diabetes). Diabetes. 2002. 51 Suppl 3. S462-73
Shin Takasawa, Hiroshi Okamoto. Pancreatic β-cell death, regeneration and insulin secretion: Roles of poly(ADP-ribose) polymerase and cyclic ADP-ribose. International Journal of Experimental Diabetes Research. 2002. 3. 2. 79-96
Okamoto H, Takasawa S, Nata K, Kato I, Tohgo A, Noguchi N. Physiological and pathological significance of the CD38-cyclic ADP-ribose signaling system. (Chem Immunol). Chem Immunol. 2000. 75. 121-145

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Education (2)：

- 1969 Kyoto University Graduate School, Division of Medicine 生理系
- 1964 Kanazawa University Faculty of Medicine 医学科

Awards (10)：

2003/06 - 日本学士院日本学士院賞実験糖尿病の発症とその防止に関する研究
2002/11 - 日本政府紫綬褒章医化学研究
1996/11 - べーリンガーインゲルハイム社ベルツ賞新しいインスリン分泌機構とその病態
1993/11 - 財団法人武田科学振興財団武田医学賞インスリン産生細胞破壊とその防止の機構(岡本モデル)の提唱とその展開
1993/05 - 日本糖尿病学会日本糖尿病学会ハーゲドーン賞膵β細胞破壊と防止についての岡本モデルとその展開

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Association Membership(s) (1)：

日本学術会議(2005/10-)

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