Yasumoto Ken-ichi

Affiliation and department：
Job title： Associate Professor
Homepage URL (2)： https://www.lifesci.tohoku.ac.jp/research/fields/laboratory.html?id=2520 , https://www.lifesci.tohoku.ac.jp/en/research/fields/laboratory.html?id=2520

Research field (3)： Cell biology , Medical biochemistry , Molecular biology

Research keywords (7)： DLK , Osmotic stress , PHD3 , Melanogenesis , Xenobiotic Response , Hypoxia , Transcriptional Regulation

Research theme for competitive and other funds (19)：

2014 - 2017 Elucidation of pathogenic mechanism of Parkinson's disease through analysis of IPAS, a novel substrate of Parkin
2006 - 2007 Visualization of the VBC complex in living cells by FLIM-FRET
2006 - 2007 外来薬物による遺伝子発現誘導における転写因子複合体の機能解析
2006 - 2007 生細胞でのAhリセプター転写複合体のイメージングと活性化機構
2005 - 2006 FRETによる単一生細胞でのPMLボディ生理機能の可視化

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Papers (71)：

Sho Tabata, Yasushi Kojima, Takeharu Sakamoto, Kaori Igarashi, Ko Umetsu, Takamasa Ishikawa, Akiyoshi Hirayama, Rie Kajino-Sakamoto, Naoya Sakamoto, Ken-Ichi Yasumoto, et al. L-2hydroxyglutaric acid rewires amino acid metabolism in colorectal cancer via the mTOR-ATF4 axis. Oncogene. 2023. 42. 16. 1294-1307
Shuya Kasai, Xianyu Li, Satoru Torii, Ken-ichi Yasumoto, Kazuhiro Sogawa. Direct protein-protein interaction between Npas4 and IPAS mutually inhibits their critical roles in neuronal cell survival and death. Cell Death Discovery. 2021. 7. 1. 300-300
Shuya Kasai, Ken-ichi Yasumoto, Kazuhiro Sogawa. Attenuation of inhibitory PAS domain protein-induced cell death by synthetic peptides derived from Mcl-1 transmenbrane domain. Cell Death Discovery. 2021. 7. 1. 92
Satoru Torii, Shuya Kasai, Tatsushi Yoshida, Ken-Ichi Yasumoto, Shigeomi Shimizu. Mitochondrial E3 Ubiquitin Ligase Parkin: Relationships with Other Causal Proteins in Familial Parkinson's Disease and Its Substrate-Involved Mouse Experimental Models. International journal of molecular sciences. 2020. 21. 4
Shuya Kasai, Mary J. E. Richardson, Satoru Torii, Ken-ichi Yasumoto, Hiroki Shima, Kazuhiko Igarashi, Ken Itoh, Kazuhiro Sogawa, Kazutaka Murayama. Increase in proapoptotic activity of inhibitory PAS domain protein via phosphorylation by MK2. FEBS JOURNAL. 2017. 284. 23. 4115-4127

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MISC (30)：

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Professional career (1)：

Awards (1)：

Association Membership(s) (4)：

The Japanese Society for Pigment Cell Research , 日本癌学会 , 日本分子生物学会 , 日本生化学会

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