Takeuchi Hiroko

Affiliation and department：

Research field (4)： Biophysics , Physiology , Neuroscience - general , Clinical pharmacy

Research keywords (26)： Ion Channel , Signal transduction , Olfactory masking , Olfactory adaptation , 感覚生理学 , Electrophysiology , Patch Clamp , Olfaction , Olfactory receptor cell , 蛍光物質 , Cilia , 生体分子 , Caged substances , UV , 生理活性 , 情報伝達 , Cyclic nucleotide , Second messenger , cAMP , Chemical Senses , AC , Sense , Real time recording , LSM , Molecular dynamics , Neruon

Research theme for competitive and other funds (9)：

2019 - 2024 嗅覚情報変換チャネルにおける興奮と抑制を修飾する分子メカニズム解明
2016 - 2020 嗅覚神経細胞における感度モジュレーションの分子メカニズム解明
2013 - 2017 Elucidation of mechanism of real-time molecular dynamics of second messengers using caged compounds
2014 - 2016 情報伝達チャネルの興奮と抑制を修飾する少数分子の機構解明
2010 - 2014 Signal transduction system of human olfactory receptor cells

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Papers (18)：

Hiroko Takeuchi, Takashi Kurahashi. Segregation of Ca2+ signaling in olfactory signal transduction. Journal of General Physiology. 2023. 155. 4
Takeuchi H, Kurahashi T. Suppression of olfactory signal transduction by insecticides. npj Science of Food. 2019. 3. 9
Tamari K, Takeuchi H, Kobayashi M, Takeuchi K, Kurahashi T, Yamamoto T. Electrical properties of cells from human olfactory epithelium. Auris Nasus Larynx. 2019. S0385-8146. 18. 30697-30697
Takeuchi H, Kurahashi T. Second messenger molecules have a limited spread in olfactory cilia. J Gen Physiol. 2018. 150. 12. 1647-1659
Hiroko Takeuchi, Hiroyuki Kato, Takashi Kurahashi. 2,4,6-Trichloroanisole is a potent suppressor of olfactory signal transduction. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013. 110. 40. 16235-16240

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MISC (1)：

MS-Windows application executing the non-stationary noise analysis of whole-cell transient current. Aroma research. 2008. 19. 3. 233-240

Books (14)：

Lippincott Ilustrated Review: Physiology, 2nd Edition
2021 ISBN:9784621306079
嗅覚のシグナルトランスダクション
Clinical Neuroscience Vol.34 (16年) 12月号嗅覚-New horizon 中外医学社 2016年12月 2019
Molecular Mechanism of Olfactory Masking by 2, 4, 6-Trichloroanisole
2019
Taste and Smell (Topics in Medicinal Chemistry)
Springer 2018 ISBN:3319840495
Topics in Medical Chemistry, Taste and Smell
Springer 2017

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Lectures and oral presentations (68)：

生体ナノチューブ構造体内物質拡散制限に関するランダムウォークモデルによる検証
(第114回近畿生理談話会 2022)
生体ナノチューブ構造体の蛍光イメージングを用いた輝度測定
(第114回近畿生理談話会 2022)
Segregation of Ca2+ signalings in olfactory signal transduction
(The 99th Annual Meeting of the Physiological Society of Japan 2022)
Diffusion dynamics analysis of substances after intracellular caged cAMP dissociation by UV laser confocal microscopy
(2021)
Functional separation of two conflicting Ca2+ signaling in olfactory cilia
(2021)

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Professional career (1)：

博士(理学) (大阪大学)

Work history (5)：

2014/04 - 現在 Osaka University Graduate School of Frontier Biosciences
2007/04 - Osaka University Graduate School of Frontier Biosciences
2005/07 - 2005/08 SISSA (International School for Advanced Studies) Neurobiology (Prof. A. Menini) Research fellow
2002/04 - Osaka University Graduate School of Frontier Biosciences
2000/04 - Osaka University Graduate School of Engineering Science

Awards (5)：

2015/07 - 大阪大学総長奨励賞(研究部門)
2015/04 - Ministry of Education, Culture, Sports, Science and Technology (MEXT) The Young Scientists’ Prize
2014/07 - 大阪大学総長奨励賞(研究部門)
2011/09 - THE FEDERATION OF THE ASIAN AND OCEANIAN PHYSIOLOGICAL SOCIETIES Young Investigator Award
2006/05 - The Physiological Society of Japan Promotion Award of the Physiological Society of Japan for Young Scientists

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