Rchr
J-GLOBAL ID：200901007993219692   Update date: Mar. 02, 2024

Oishi Tohru

オオイシ トオル | Oishi Tohru
Affiliation and department：
Kyushu University Faculty of Sciences Department of Chemistry

About Kyushu University Faculty of Sciences Department of Chemistry


Job title： Associate Professor
Homepage URL  (1)： http://www.scc.kyushu-u.ac.jp/Seibutsuyuki/index.htm
Research field  (2)： Bioorganic chemistry ,  Structural/physical organic chemistry
Research keywords  (5)： 有機合成化学 ,  天然物化学 ,  Bioorganic Chemistry ,  Synthetic Organic Chemistry ,  Natural Products Chemistry
Research theme for competitive and other funds  (33)：
  • 2023 - 2026 Structure-Activity Relationship Study of Maitotoxin Based on Chemical Synthesis
  • 2021 - 2024 Development of a novel antifungal agent based on the membrane acting molecule which discriminate human and fungal membrane
  • 2019 - 2022 Design and synthesis of calcium ion regulatory molecules based on maitotoxin
  • 2018 - 2020 Elucidation of stereochemistry and biological function by total synthesis of super-carbon-chain natural products
  • 2016 - 2019 Elucidation of mode-of-action of maitotoxin based on chemical synthesis
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Papers (120)：
  • Masahiro Kaneko, Atsuhiro Yamashita, Yoko Yasuno, Kosei Yamauchi, Ken Sakai, Tohru Oishi. Synthesis of the MN Ring of Caribbean Ciguatoxin C-CTX-1 via Desymmetrization by Acetal Formation. Organic Letters. 2024. 26. 4. 855-859
  • Nobuaki Matsumori, Manami Hieda, Masayuki Morito, Yuma Wakamiya, Tohru Oishi. Truncated derivatives of amphidinol 3 reveal the functional role of polyol chain in sterol-recognition and pore formation. Bioorganic & Medicinal Chemistry Letters. 2024
  • Yuichi Umegawa, Tomoya Yamamoto, Mayank Dixit, Kosuke Funahashi, Sangjae Seo, Yasuo Nakagawa, Taiga Suzuki, Shigeru Matsuoka, Hiroshi Tsuchikawa, Shinya Hanashima, et al. Amphotericin B assembles into seven-molecule ion channels: An NMR and molecular dynamics study. Science advances. 2022. 8. 24. eabo2658
  • Keitaro Umeno, Hisaaki Onoue, Keiichi Konoki, Kohei Torikai, Yoko Yasuno, Masayuki Satake, Tohru Oishi. Convergent Synthesis of the WXYZA′B′C′D′E′F′ Ring Segment of Maitotoxin. Bulletin of the Chemical Society of Japan. 2022. 95. 2. 325-330
  • Yuta Watanabe, Kohei Torikai, Yoko Yasuno, Tohru Oishi. Synthetic study of the c'd'e' ring system of maitotoxin via furan based strategy. Heterocycles. 2021. 102. 12. 2313-2318
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MISC (106)：
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Lectures and oral presentations  (1)：
  • Total Synthesis of Amphidinol 3
    (Pacifichem 2021 2021)
Works (4)：
  • Synthesis of Diacylglycerols
    1995 - 2000
  • Z-Selective Horner-Wadsworth-Emmons Reaction
    1999 -
  • The absolute configuration and total synthesis of korormicin
    1997 -
  • ユウレイボヤ精子活性化物質の作用機構解明
Education (4)：
  • - 1992 Tohoku University
  • - 1992 Tohoku University Graduate School, Division of Natural Science
  • - 1987 Tohoku University Faculty of Science
  • - 1987 Tohoku University Faculty of Science
Professional career (1)：
  • Doctor of Science (Tohoku University)
Work history (11)：
  • 2010 - 現在 Kyushu University Graduate School of Science Professor
  • 2002 - 2010 Osaka University Graduate School of Science
  • 2000 - 2002 Osaka University Graduate School of Science
  • 2000 - 2002 Graduate School of Science, Osaka University, Lecturer
  • 2002 - - Graduate School of Science, Osaka University, Associate Professor
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Committee career (1)：
  • 2000 - 有機合成化学協会 編集協力委員
Awards (6)：
  • 2023/04 - Nagase Science and Technology Foundation Nagase Foundation Award 2023 Design and synthesis of molecules that control Ca2+ influx based on marine natural toxin maitotoxin
  • 2022/02 - Chemical Society of Japan BCSJ Award Convergent Synthesis of the WXYZA’B’C’D’E’F’ Ring Segment of Maitotoxin.
  • 2019/03 - The Chemical Society of Japan The Chemical Society of Japan Award for Creative Work for 2018 Structure Determination, Chemical Synthesis, and Evaluation of Biological Activity of Super Carbon Chain Natural Products
  • 2016 - Asian Core Program (ACP) Advanced Research Network Lectureship Award (2016)
  • 2001 - BCSJ賞
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Association Membership(s) (3)：
有機合成化学協会 ,  アメリカ化学会 ,  日本化学会
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