Rchr
J-GLOBAL ID：200901008910449450   Update date: Mar. 01, 2024

OKUDA Akihiko

オクダ アキヒコ | OKUDA Akihiko
Affiliation and department：
Saitama Medical University Faculty of Medicine

About Saitama Medical University Faculty of Medicine


Job title： Professor
Homepage URL  (1)： http://www.saitama-med.ac.jp/uinfo/biomedsci/
Research theme for competitive and other funds  (21)：
  • 2023 - 2026 非生殖細胞での減数分裂関連遺伝子の異所的な発現を抑制するための分子基盤の解明
  • 2023 - 2026 ポリコーム複合体による減数分裂に対する抑制を生殖細胞が解除する仕組みの解明
  • 2021 - 2024 哺乳類生殖細胞の減数分裂開始機構の解明
  • 2022 - 2023 株式会社金太郎セルズパワー・メディカルガスの線維芽細胞に対する増殖効果についての検討
  • 2019 - 2022 Elucidation of the molecular bases of inverse correlation between Max expression level and meiotic onset
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Papers (71)：
  • Yuka Kitamura, Ayumu Suzuki, Kousuke Uranishi, Masazumi Nishimoto, Seiya Mizuno, Satoru Takahashi, Akihiko Okuda. Alternative splicing for germ cell-specific Mga transcript can be eliminated without compromising mouse viability or fertility. Development, Growth & Differentiation. 2022. 64. 7. 409-416
  • Kousuke Uranishi, Masataka Hirasaki, Yuka Kitamura, Yosuke Mizuno, Masazumi Nishimoto M, @Ayumu Suzuki, @Akihiko Okuda. Two DNA binding domains of MGA act in combination to suppress ectopic activation of meiosis-related genes in mouse embryonic stem cells. STEM CELLS. 2021. 39. 11. 1435-1446
  • Takanari Nakano, Hidekazu Aochi, Masataka Hirasaki, Yasuhiro Takenaka, Koji Fujita, Masaru Tamaru, Hiroaki Soma, Hajime Kamezawa, Takehiro Koizumi, Hirotoshi Shibuya, et al. Effects of Pparγ1 deletion on late-stage murine embryogenesis and cells that undergo endocycle. Developmental Biology. 2021. 478. 222-235
  • Yuka Kitamua, Kousuke Uranishi, Masataka Hirasaki, Masazumi Nishimoto, @Ayumu Suzuki, @Akihiko Okuda. Identification of germ cell-specific Mga variant mRNA that promotes meiosis via impediment of non-canonical PRC1. Scientific Reports. 2021. 11. 1. ---
  • Masazumi Nishimoto, Kousuke Uranishi, Masamitsu Asaka, Ayumu Suzuki, Yosuke Mizuno, Masataka Hirasaki, and Akihiko Okuda. Transformation of normal cells by aberrant activation of YAP via cMyc with TEAD. Scientific Reports. 2019. 9. 1. 10933
ｍore...
Lectures and oral presentations  (90)：
  • MAX regulates the meiosis-related genes in mouse germ cells
    (2022)
  • Interaction between Mga and Atf7ip contributes to establishment of heterochromatin in meiosis-related genes.
    (2022)
  • Generation of meiotic germ cell-specific Mga splice variant for promoting meiotic onset via inactivation of non-canonical PRC1
    (第43回日本分子生物学会年会 2020)
  • Mammalian germ cell meiotic initiation is regulated by MAX
    (第43回日本分子学会年会 2020)
  • Max knock-out embryonic stem cells are useful tools to study meiotic initiation in mammals
    (MBSJ2019 2019)
ｍore...
Education (2)：
  • 1984 - 1988 The University of Tokyo Graduate School, Division of Medical Sciences
  • 1978 - 1984 Hiroshima University Faculty of Medicine
Professional career (1)：
  • 博士(医学) (東京大学)
Work history (9)：
  • 2020/04 - 現在 埼玉医科大学 医学部 ゲノム基礎医学 教授
  • 2005/09 - 現在 Professor
  • 2001/07 - 2005/08 Associate Professor
  • 1992/12 - 2001/06 Lecturer
  • 1990/02 - 1992/12 米国カリフォルニア工科大学化学科 研究員・ポスドク
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Committee career (9)：
  • 2018/06 - 現在 中冨健康科学振興財団評議員 評議員
  • 2017/07/01 - 現在 倫理委員会委員 委員
  • 2017/07 - 現在 東京都健康長寿医療センター 臨床研究審査委員会委員 委員
  • 2017/07 - 現在 東京都健康長寿医療センター 研究倫理審査委員会委員 委員
  • 2018/06/15 - 2018/07/05 日本学術振興会 卓越大学院プログラムにおける審査意見書作成について
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