Nishizawa Kazuhisa

ニシザワカズヒサ | Nishizawa Kazuhisa

Affiliation and department：
Job title： Director
Other affiliations (1)：

NIK Biomolecular Research Group

Homepage URL (1)： http://orcid.org/0000-0002-7642-6054

Research field (8)： Structural biochemistry , Biophysics , Nanobioscience , Medical biochemistry , Chemical biology , Clinical pharmacy , Physiology , Molecular biochemistry

Research keywords (7)：分子進化 , 構造化学 , 計算化学 , computational biophysics , 分子医化学 , Genetics , Biophysics

Research theme for competitive and other funds (7)：

2016 - 2019 Physiological role of voltage-sensing phosphatase in mammals
2009 - 2011 Atomistic molecular dynamics simulation analysis of molecular physiological problems involving ion channel activity regulation
2004 - 2005 Molecular simulation - based analysis of signal transduction system in neuronal cells
1999 - 2000 浸透圧ストレス応答としての硫酸化糖脂質発現制御機序の解明
イオンチャネルの分子動力学シミュレーション// 脂質膜融合促進ペプチドの作用機序// 脂質膜とタンパク質の相互作用の理論および実験による解析

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Papers (52)：

Reiko Seki, Riku Miyawaki, Akane Matsuda, Kazuhisa Nishizawa. Rapid Decrease and Subsequent Increase in the Serum Triglycerides Accompanied by <i>CD36</i> Transcript Increase in an Acute Stress Mice Model. Journal of Biosciences and Medicines. 2022. 10. 10. 98-107
Seki R, Nishizawa K. Serum Urea Nitrogen Level Shows Stronger Correlations with Metabolic Syndrome Risk Factors in Women Than in Men in a Japanese General Population. FRONTIERS IN MEDICINE AND HEALTH RESEARCH. 2020. 2. 109
Why does Adiposity Associate with Hyperuricemia more Strongly in Women than in Men? A Question-oriented Review and Hypothesis. 2020. 3. 120
Reiko Seki, Kazuhisa Nishizawa. Use of TLR9 and TLR7/8 agonists in combination with D-galactosamine in exploring models for distinct severities of systemic inflammation relative to liver injury. Physiological Research (in press). 2020. 1125-1129
Kazuhisa Nishizawa, Reiko Seki. Epidemiological Studies of Uric Acid: A Mini-review with a Focus on Mendelian Randomization. Annals of Biomedical Research. 2020. 3. 1. 119

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MISC (4)：

西澤和久. Editorial--- Phage display libraries in sequelization of autoantibody signature analyses in cancer immunomics. Biomedical Research and Clinical Practice. 2017. 2. 4
Radhakrishnan Gnanasambandam, Kazuhisa Nishizawa, Frederick Sachs, Thomas Suchyna. Positively Charged Residues on GsMTx4 are Crucial for Inhibition of the Mechanosensitive Ion Channel Piezo1. BIOPHYSICAL JOURNAL. 2013. 104. 2. 467A-467A
Kazuhisa Nishizawa. Molecular Dynamics Simulations of Kv Channels and Gating-Modifier Peptide Toxins. CURRENT COMPUTER-AIDED DRUG DESIGN. 2009. 5. 3. 155-173
Nishizawa M and Nishizawa K Curvature-driven lipid sorting: coarse-grained dynamics simulations of a membrane mimicking a hemifusion intermediate J Biophys Chem (2010) (in press) .......................Nishizawa M, Nishizawa K. Molecular dynamics sim・・・

Patents (1)：

米国特許(Cloning and characterization of a CDC15-like adapter protein CD2BP1(Patent No:US 6,444,439 B1; Sep.3, 2002))

Books (6)：

Atomistic molecular simulation of gating modifier venom peptides: two binding modes and effects of lipid structure.
in Mechanosensitivity of Cells and Tissues: Mechanosensititvity and Mechanotransduction by Andre Kamkin ed 2010
Molecular Dynamics Simulations of Kv Channels and Gating-Modifier Peptide Toxins
2009
Local repetitiveness and slippage-like mutations in genomic sequences.
2003
翻訳とmRNAの制御
高等動物の分子生物学(朝倉書店) 1998
遺伝子制御,遺伝子発現(他20項目)
分子細胞生物学辞典(東京化学同人) 1997

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Lectures and oral presentations (6)：

電位依存性ホスファターゼにおける膜相互作用の動態と役割,
(第94回日本生理学会大会 2017)
Roles of membrane interaction in electrochemical coupling of voltage-sensing phosphatase
(Cold Spring Harbor Laboratory Symposium on Membrane Proteins: Structure & Function 2017 . 2017)
東京医科歯科大学_大学院講義
(脂質膜と膜タンパク質の分子動力学シミュレーション解析 2014)
大阪大学医学部_講義
(選択科目_生体情報科学 2013)
Positively Charged Residues on GsMTx4 are Crucial for Inhibition of the Mechanosensitive Ion Channel Piezo1
(Annual meeting of Biophysical Society_(Biophys J, vol 104:467a) 2012)

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Works (5)：

医療技術学部FD委員会委員長 2015-2019年度
西澤和久
帝京大学遺伝子組換え生物実験安全委員会委員長平成18-23年度(平成19-23年度安全主任者兼任)
西澤和久
ホームページ作成および問題集の掲載, 暗証番号による成績速報の整備
西澤和久
問題集の作成(「国家試験対策-臨床化学生化学-正文集」)
西澤和久
参考図書の翻訳「一目でわかる医科生化学」(メディカルサイエンスインターナショナル)
西澤和久

Education (4)：

- 1994 The University of Tokyo
- 1994 The University of Tokyo Graduate School, Division of Medical Sciences
- 1989 The University of Tokyo Faculty of Medicine School of Medicine
- 1989 The University of Tokyo Faculty of Medicine

Professional career (1)：

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Work history (6)：

2022/04 - 現在 Biomolecular Logic Research Laboratory (代表)
2021/10 - 現在 NIK-Biomolecular Research Group
2006 - 2022/03 - 帝京大学医療技術学部臨床検査学科教授 (2006年学科長)
1995 - 1998 Postdoctral fellow at Laboratory of Immunobiology, Dana-Farber Cancer Institute, Harvard Medical School. (Dr Reinherz lab; Teikyo-Harvard fellowshipによる)
1998 - - 帝京大学医学部第二生化学 1998年講師, 2003年助教授

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Committee career (11)：

2017/12 - 現在 Editor-in-Chief _____Annals of Biomedical Research_____ http://escires.com/annals-of-biomedical-research
2017/03 - 現在 Editor-in-Chief ___ J. Biophys. Chem___http://www.scirp.org/journal/jbpc
2013/02 - 現在 Editorial Board Member of____ BioMed Research International___area of Computational Biology_http://www.hindawi.com/journals/bmri/editors/computational.biology/
2013/02 - 現在 Editorial Board member of_ BioMed Research International__area of computational biology________http://www.hindawi.com/journals/bmri/editors/computational.biology/
2012 - 現在 Editoral Board member of_______ International Scholarly Research Notice --area of Biophysics

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Association Membership(s) (2)：

THE BIOPHYSICAL SOCIETY OF JAPAN , Biophysical society

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