Rchr
J-GLOBAL ID：200901009610377764   Update date: Feb. 01, 2024

Itoh Motoyuki

ITOH MOTOYUKI | Itoh Motoyuki
Affiliation and department：
Chiba University

About Chiba University


Homepage URL  (1)： http://www.p.chiba-u.jp/lab/seika/index.html
Research field  (5)： Laboratory animal science ,  Pharmaceuticals - health and biochemistry ,  Developmental biology ,  Cell biology ,  Molecular biology
Research keywords  (9)： Dementia ,  metabolism ,  Aging ,  Brain function ,  Wntシグナル ,  Notchシグナル ,  神経発生 ,  ゼブラフィッシュ ,  zebrafish neural development Notch signaling Wnt signaling
Research theme for competitive and other funds  (19)：
  • 2022 - 2025 Elucidation of the molecular and neural basis that controls the environmental factor-dependent forgetting mechanism
  • 2021 - 2025 Integrative analysis of mechanisms of neurological abnormalities due to aging and pathological background
  • 2021 - 2024 ゲノムジャンク領域にコードされる機能ペプチドの制御機構の情報学的推定と実験的検証
  • 2021 - 2024 非コード領域・タンパク構造情報を含むオミクス統合解析に基づく精密医療の実現
  • 2020 - 2023 Pathophysiological roles of cell senescence related gene in the polycystic kidney disease
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Papers (62)：
  • Sizhe Lyu, Noritaka Terao, Hirofumi Nakashima, Motoyuki Itoh, Ayako Tonoki. Neuropeptide diuretic hormone 31 mediates memory and sleep via distinct neural pathways in Drosophila. Neuroscience research. 2023. 192. 11-25
  • Xue Hou, Reina Hayashi, Motoyuki Itoh, Ayako Tonoki. Small-molecule screening in aged Drosophila identifies mGluR as a regulator of age-related sleep impairment. Sleep. 2023. 46. 5
  • Tohgo Kanoh, Jingyu Lu, Takamasa Mizoguchi, Motoyuki Itoh. The E3 ubiquitin ligase MIB1 suppresses breast cancer cell migration through regulating CTNND1 protein level. Biochemical and Biophysical Research Communications. 2023
  • Takamasa Mizoguchi, Shohei Mikami, Mari Yatou, Yui Kondo, Shuhei Omaru, Shuhei Kuwabara, Wataru Okura, Syouta Noda, Takeshi Tenno, Hidekazu Hiroaki, et al. Small-Molecule-Mediated Suppression of BMP Signaling by Selective Inhibition of BMP1-Dependent Chordin Cleavage. International Journal of Molecular Sciences. 2023. 24. 5
  • Ayako Tonoki, Saki Nagai, Zhihua Yu, Tong Yue, Sizhe Lyu, Xue Hou, Kotomi Onuki, Kaho Yabana, Hiroki Takahashi, Motoyuki Itoh. Nitric oxide-soluble guanylyl cyclase pathway as a contributor to age-related memory impairment in Drosophila. Aging cell. 2022. e13691
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MISC (47)：
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Books (1)：
  • ゼブラフィッシュ実験ガイド
    朝倉書店 2020 ISBN:9784254171730
Works (3)：
  • 個体発生期におけるNotchシグナル伝達経路の時空間的統合理解
    2007 -
  • Notch, LEF1転写複合体の活性制御機構の解明
    2006 -
  • 細胞動態に着目した側線発生機構の解明
    2006 -
Education (3)：
  • 1994 - 1998 Osaka University
  • 1991 - 1993 Osaka University Graduate School of Pharmaceutical Sciences
  • 1987 - 1991 Osaka University
Professional career (1)：
  • Ph.D (Osaka University)
Work history (12)：
  • 2012/05 - Chiba University Graduate School of Pharmaceutical Sciences
  • 2011/04 - Nagoya University
  • 2006/11 - Nagoya University Nagoya University
  • 2006 - - 特任准教授
  • 2003/07 - Nagoya University Graduate School of Science
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Committee career (3)：
  • 2020/06 - 現在 猪鼻奨学会 評議員
  • 2007/04 - 現在 ナショナルバイオリソースプロジェクト「ゼブラフィッシュ」 運営委員
  • 2017/02 - 2019/01 日本薬学会 代議員(関東支部幹事)
Awards (1)：
  • 2015/10 - 日本学術振興会 科研費第1段審査(書面審査)委員表彰
Association Membership(s) (5)：
The Engineering Academy of Japan ,  The Molecular Biology Society of Japan ,  アメリカ神経科学会 ,  日本薬学会 ,  日本分子生物学会
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