Rchr
J-GLOBAL ID:200901010064155044   Update date: Oct. 24, 2023

Hatano Akihiko

ハタノ アキヒコ | Hatano Akihiko
Affiliation and department:
Job title: Prof.
Homepage URL  (1): https://www.a-hatano-lab.com/
Research field  (6): Chemical biology ,  Pharmaceuticals - chemistry and drug development ,  Bioorganic chemistry ,  Synthetic organic chemistry ,  Molecular biochemistry ,  Applied biofunctional and bioprocess engineering
Research keywords  (5): 酵素工学 ,  生物有機化学 ,  Synthetic Chemistry ,  ケミカルバイオロジー ,  生体関連化学
Research theme for competitive and other funds  (14):
  • 2021 - 2024 血管新生因子をターゲットとした癌細胞特異的蛍光プローブの開発
  • 2018 - 2022 Cancer cell-specific imaging with the fluorescent probe responding by thymidine phosphorylase
  • 2012 - 2015 Synthesis of the variety nucleostide probes produced by synchronization of the biocatalyst and the palladium catalyst
  • 2014 - 2015 人工核酸を用いた細胞内レドックス環境のセンシングとイメージング
  • 2012 - 2013 核酸代謝酵素を利用した安定同位体導入ヌクレオシドの効率的合成
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Papers (34):
  • Genki SHIMANE, Nanae Terado, Akihiko HATANO. Chemoenzymatic synthesis of unnatural nucleoside with stable isotopes. 3rd Japan-Switzerland-Germany Workshop on Biocatalysis and Bioprocess Development, 2023. 2023. P28
  • Rai Hamano, Akihiko Hatano, Riki Matsuzaka. Synthesis of pentostatin precursor with pyrimidine nucleoside phosphorylase. 3rd Japan-Switzerland-Germany Workshop on Biocatalysis and Bioprocess Development, 2023. 2023. P24
  • Akihiko Hatano, Riki Matsuzaka, Genki Shimane, Hiroyuki Wakana, Kou Suzuki, Chisato Nishioka, Aoi Kojima, Masatoshi Kidowaki. Introduction of pseudo-base benzimidazole derivatives into nucleosides via base exchange by a nucleoside metabolic enzyme. Bioorganic & Medicinal Chemistry. 2023. 91. 117411-117411
  • Saki Endo, Mahiro Sarai, Akihiko Hatano, Kenichi Niikura. Supramolecular Conjugation between 18-Crown 6-Ether and Tannic Acid with Unique pH Responsiveness. Chemistry Letters. 2023
  • Rei HAMANO, Koichi OTSUKIi, Akihiko HATANO. Effects of Functional Groups Recognition of Nucleoside Structure for Phosphorolysis with Pyrimidine Nucleoside Phosphorylase PyNP. SEATUC 2023. 2023
more...
MISC (20):
Patents (4):
  • ヌクレオシド化合物の製造方法およびヌクレオシド化合物含有組成物
  • ヌクレオシド化合物の製造方法
  • 免疫測定用試薬及び免疫測定法
  • C-ヌクレオシド又はC-ヌクレオチド
Works (2):
  • 新規生理活性物質の合成と探索研究 (パーマケムアジア社)
    2004 -
  • 岩城製薬 (βアミロイドタンパクの構造転移制御)
    2002 -
Education (6):
  • - 2000 The Graduate University for Advanced Studies
  • - 2000 The Graduate University for Advanced Studies Graduate School, Division of Mathematical and Physical Science
  • - 1993 Tokyo Institute of Technology Bioscience and Biotechnology
  • - 1993 Tokyo Institute of Technology Graduate School, Division of Life Science and Engineering
  • - 1991 University of Fukui Faculty of Engineering
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Professional career (2):
  • (BLANK) (Tokyo Institute of Technology)
  • Dr. of Science (The Graduate University for Advanced Studies)
Work history (7):
  • 2014/04 - 現在 Shibaura Institute of Technology College of Engineering
  • 2008/04 - 2014/03 Shibaura Institute of Technology College of Engineering
  • 2000/10 - 2008/04 Shizuoka Institute of Science and Technology Faculty of Science and Technology
  • 1999 - 2000 日本学術振興会 特別研究員
  • 1999 - 2000 JSPS Research Fellowships
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Committee career (2):
  • 2019/04 - 2022/03 日本化学会関東支部 化学クラブ実行委員
  • 2002 - 日本化学会 トピックス編集委員
Awards (2):
  • 2005 - ITE award
  • 2002 - 有機合成化学協会 研究企画賞 (第一製薬)
Association Membership(s) (5):
日本薬学会 ,  生命化学研究会 ,  日本化学会 ,  酵素工学研究会 ,  高分子学会
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