Rchr
J-GLOBAL ID:200901010520519509   Update date: Jan. 30, 2024

Sakurai Fuminori

サクライ フミノリ | Sakurai Fuminori
Affiliation and department:
Research field  (3): Clinical pharmacy ,  Pathobiochemistry ,  Pharmacology
Research keywords  (2): Gene Therapy, DDS, Biopharmaceutics, Pharmacokinetics ,  Gene Therapy
Research theme for competitive and other funds  (23):
  • 2021 - 2025 難治性がん治療用デザイナー細菌の開発
  • 2022 - 2024 血管を経由する新発想での臓器の脱線維化技術の開発
  • 2021 - 2024 A study of drug repurposing of oncolytic virus for idiopathic pulmonary fibrosis
  • 2021 - 2024 Elucidation of oncolytic virus-mediated intratumorl infiltration of immune cells and development of further promotion methods
  • 2020 - 2023 血管透過性を抑制する新機序で作用する炎症疾患治療薬の開発
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Papers (192):
  • Kahori Shimizu, Moe Ono, Takenari Mikamoto, Yuya Urayama, Sena Yoshida, Tomomi Hase, Shotaro Michinaga, Hiroki Nakanishi, Miho Iwasaki, Tomoyuki Terada, et al. Overexpression of lysophospholipid acyltransferase, LPLAT10/LPCAT4/LPEAT2, in the mouse liver increases glucose-stimulated insulin secretion. The FASEB Journal. 2024. 38. 2
  • Sena Ikemoto, Fuminori Sakurai, Sora Tokuoka, Tomoki Yamashita, Kosuke Takayama, Kazuaki Hoshi, Takahiro Okabe, Issei Sumiyoshi, Shinsaku Togo, Kazuhisa Takahashi, et al. Novel conditionally replicating adenovirus-mediated efficient detection of circulating tumor cells in lung cancer patients. PLOS ONE. 2023. 18. 10. e0286323-e0286323
  • Takuma Hotani, Kanako Nakagawa, Tomohito Tsukamoto, Hiroyuki Mizuguchi, Fuminori Sakurai. Involvement of Protein Kinase R in Double-Stranded RNA-Induced Proteasomal Degradation of Hypoxia Inducible Factor-1α. Inflammation. 2023
  • Eiko Sakai, Tsutomu Imaizumi, Ruruka Suzuki, Marcos Taracena-Gándara, Toshiki Fujimoto, Fuminori Sakurai, Hiroyuki Mizuguchi. miR-27b targets MAIP1 to mediate lipid accumulation in cultured human and mouse hepatic cells. Communications biology. 2023. 6. 1. 669-669
  • Haoyang Zhou, Zhiqi Xie, Naosuke Morikawa, Fuminori Sakurai, Hiroyuki Mizuguchi, Daisuke Okuzaki, Naoki Okada, Masashi Tachibana. Modified method for differentiation of myeloid-derived suppressor cells in vitro enhances immunosuppressive ability via glutathione metabolism. Biochemistry and biophysics reports. 2023. 33. 101416-101416
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MISC (67):
  • 櫻井文教, 井上智重子, 種昂なお実, 神宮司健太郎, 神宮司健太郎, 辻川和丈, 辻川和丈, 水口裕之, 水口裕之, 水口裕之, et al. レオウイルス感染がん細胞由来細胞外小胞のがん細胞に対する殺細胞効果の検討. 日本DDS学会学術集会プログラム予稿集. 2021. 37th
  • Keisaku Wakabayashi, Fuminori Sakurai, Ryosuke Ono, Toshiyoshi Fujiwara, Hiroyuki Mizuguchi. Development of a Novel Oncolytic Adenovirus Expressing a Short-hairpin RNA Against Cullin 4A. Anticancer research. 2020. 40. 1. 161-168
  • Masahisa Hemmi, Masashi Tachibana, Natsuki Fujimoto, Masaki Shoji, Fuminori Sakurai, Kouji Kobiyama, Ken J. Ishii, Shizuo Akira, Hiroyuki Mizuguchi. Type I IFN signaling induces Th17 cells capable of promoting gut-mucosal CTLs following intramuscular vaccination of an adenovirus vector. CYTOKINE. 2017. 100. 150-150
  • Kahori Shimizu, Sakurai Fuminori, Shunsuke Iizuka, Masashi Tachibana, Toru Nishinaka, Tomoyuki Terada, Hiroyuki Mizuguchi. Adenovirus Vector-Induced Hepatotoxicity During the Early Phase of Adenoviral Treatment Is Attributed to Inflammatory Cytokine-Induced Leaky Expression of Adenovirus Genes. MOLECULAR THERAPY. 2017. 25. 5. 264-265
  • F. Sakurai, T. Kaminade, M. Tachibana, H. Mizuguchi. Reovirus-mediated efficient killing of cancer-associated fibroblasts. HUMAN GENE THERAPY. 2016. 27. 11. A86-A86
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Books (15):
  • 腫瘍溶解性ウイルスによる抗腫瘍免疫の活性化とがん免疫療法との併用
    Drug delivery system 2023
  • アデノウイルスベクターワクチンの現状と展望
    Drug delivery system 2022
  • ヒト35型アデノウイルスを基本骨格とした腫瘍溶解性アデノウイルスの開発
    BIO Clinica 2022
  • アデノウイルスってどんなものでしたっけ?
    日経メディカル(オンライン掲載) 2021
  • ヒトiPS細胞由来肝細胞のB型肝炎ウイルス感染評価系への応用
    ファルマシア 2020
more...
Lectures and oral presentations  (19):
  • Antifibrotic effects of oncolytic reovirus
    (The 29th Annual Meeting of Japan Society of Gene and Cell Therapy 2023)
  • Development of a novel oncolytic adenovirus composed of human adenovirus serotype 35
    (The 29th Annual Meeting of Japan Society of Gene and Cell Therapy 2023)
  • Development of a replication-incompetent adenovirus vector and oncolytic adenovirus containing microRNA-mediated post-transcriptional de-targeting system
    (2022)
  • Methods of production, propagation, and purification of adenovirus vectors
    (2021)
  • Development of a novel oncolytic adenovirus based on adenovirus serotype 35
    (2021)
more...
Education (4):
  • 1996 - 2001 京都大学大学院 薬学研究科 薬品動態制御学分野
  • - 2001 Kyoto University Graduate School of Phamacentical Sciences Drug Delivery System
  • 1992 - 1996 Kyoto University Faculty of Pharmaceutical Sciences
  • - 1996 Kyoto University Faculty of Pharmaceutical Sciences
Professional career (1):
  • Doctor(Pharmacy) (Kyoto University)
Work history (5):
  • 2010/04 - 現在 Osaka University Graduate School of Pharmaceutical Sciences
  • 2013/04 - 2017/03 大阪大学大学院薬学研究科 創薬臨床研究推進分野 核酸医薬評価学 准教授(兼任)
  • 2014/08 - 2016/07 Ministry of Education,Culture,Sports,Science and Technology
  • 2005/04 - 2010/03 National Institutes of Biomedical Innovation, Health and Nutrition
  • 2003/04 - 2005/03 国立医薬品食品衛生研究所 研究官
Committee career (10):
  • 2022/08 - 現在 日本遺伝子細胞治療学会 幹事
  • 2022/04 - 現在 文部科学省 科学技術・学術政策研究所 科学技術予測センター 専門調査員
  • 2018/07 - 現在 日本遺伝子細胞治療学会 評議員
  • 2017/08 - 現在 日本DDS学会 評議員
  • 2016/07 - 現在 日本遺伝子細胞治療学会 若手ワーキンググループメンバー
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Awards (8):
  • 2018/07 - 日本遺伝子細胞治療学会 タカラバイオ賞
  • 2017/03 - 大阪大学 薬友会賞(研究部門)
  • 2016/07 - 大阪大学 総長奨励賞
  • 2015/07 - 大阪大学 総長奨励賞
  • 2015/06 - 公益財団法人臨床薬理研究振興財団 研究大賞
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Association Membership(s) (12):
THE JAPANESE SOCIETY of IMMUNOTOXICOLOGY ,  THE JAPANESE SOCIETY FOR VIROLOGY ,  日本癌学会 ,  日本DDS学会 ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  日本遺伝子細胞治療学会 ,  アメリカ遺伝子治療学会 ,  The Japanese Cancer Association ,  Japan Society of Drug Delivery System ,  The Japan Society of Gene Therapy ,  American Society of Gene Therapy ,  The Academy of Pharmaceutical Science and Technology, Japna
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