Research field (4)：
Experimental pathology
, Developmental biology
, Molecular biology
, Functional biochemistry
Research theme for competitive and other funds (24)：
2020 - 2023 IL-18のがん治療における新たな抑制シグナルの解明
2018 - 2022 Potential for IL-18 immunotherapy targeting tumor-associated macrophages
2018 - 2021 Inhibition of lymphatic metastasis in oral squamous cell carcinoma with the new anti-lymphangiogenic factor
2017 - 2020 Elucidation of new physiological function of IL-18
2015 - 2018 Inibition of lymphangiogenesis in oral squamous cell carcinoma
2014 - 2017 Effect of IL-22 on immune response against periodontal bacteria
2014 - 2017 Potential role of IL-1 family cytokines in periodontal diseases
2012 - 2015 Inhibition of inducing multidrug resistance in human osteosarcoma cells by histone deacetylase inhibitor and DNA methylation inhibitor
2011 - 2013 The effect of IL-22 on biological activity of periodontal ligament cells
2011 - 2013 Identification and the elucidation of the mechanism of interleukin 18 induced metastasis inhibitory factor(s)
2008 - 2010 The effects of IL-35 on periodontal diseases
2008 - 2010 A study on the effects of products from non-hemocyte cells activated by crosslinking HLA-II molecules on Th-cell differentiation in periodontal diseases
2008 - 2010 Identification of IL-18-induced Tumor-Cell Migration Inhibitory Factor(s) and Elucidation of its Action Mechanism..
2007 - 2009 A study on the effect of periodontal diseases on the onset and progression of steatohepatitis.
2006 - 2007 IL-18により誘導される血清中の転移抑制因子の解析
2006 - 2007 A study for the involvement of IL-22 in the pathogenesis of periodontal diseases
2003 - 2005 IL-18による破骨細胞分化制御の分子機構の解明
2002 - 2004 Mitochondrial pathway of apoptosis in target organs of sex steroid hormones
2001 - 2002 IL-18による破骨細胞の骨収吸抑制の分子機構の解明
2001 - 2001 腫瘍の骨破壊性骨転移のインターロイキン18による治療
2000 - 2001 Molecular mechanism ofapoptosis in target organs of sex steroid hormones
悪性腫瘍の治療に関する基礎的検討
破骨細胞の分化及び骨吸収機能におけるIL-18の役割
Analysis of bone-absorption mechanism by osteoclast
