Suzuki Takeshi

スズキタケシ | Suzuki Takeshi

Affiliation and department：
Other affiliations (1)：

Kanazawa University Institute for Frontier Science Initiative

Research field (4)： Medical biochemistry , Molecular biology , Cell biology , Virology

Research keywords (5)：がん遺伝子 , 腫瘍ウイルス , ゲノム情報 , エピジェネティクス , エピトランスクリプトーム

Research theme for competitive and other funds (20)：

2022 - 2025 腫瘍細胞の上皮間葉転換におけるエピゲノム・エピトランスクリプトーム制御
2019 - 2022 Functional analysis of lncRNAs in cancer development identified by genome-wide retroviral insertional mutagenesis
2018 - 2021 Search and function elucidation of lncRNAs that regulate epithelial-mesenchymal transition
2015 - 2018 Functional analysis of epigenetic regulators in cancer development identified by retroviral insertional mutagenesis
2012 - 2015 Functional characterization of epigenetic regulatory factors identified by retroviral insertional mutagenesis

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Papers (62)：

Gerelsuren Batbayar, Akihiko Ishimura, Hanbing Lyu, Sasithorn Wanna-Udom, Makiko Meguro-Horike, Minoru Terashima, Shin-Ichi Horike, Takahisa Takino, Takeshi Suzuki. ASH2L, a COMPASS core subunit, is involved in the cell invasion and migration of triple-negative breast cancer cells through the epigenetic control of histone H3 lysine 4 methylation. Biochemical and biophysical research communications. 2023. 669. 19-29
Kusuma Suphakhong, Minoru Terashima, Sasithorn Wanna-Udom, Risa Takatsuka, Akihiko Ishimura, Takahisa Takino, Takeshi Suzuki. m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-β-induced epithelial-mesenchymal transition of lung cancer cells. The Journal of biological chemistry. 2022. 298. 11. 102554-102554
Hirari Yamahana, Minoru Terashima, Risa Takatsuka, Chikako Asada, Takeshi Suzuki, Yoshihiro Uto, Takahisa Takino. TGF-β1 facilitates MT1-MMP-mediated proMMP-9 activation and invasion in oral squamous cell carcinoma cells. Biochemistry and biophysics reports. 2021. 27. 101072-101072
Saifullah Saifullah, Matomo Sakari, Takeshi Suzuki, Seiji Yano, Toshifumi Tsukahara. P28-11 The CRISPR-Cas13a gene-editing system underlies a potential therapeutic strategy for EML4-ALK-positive lung cancer cells. Annals of Oncology. 2021. 32. S347-S347
Sasithorn Wanna-Udom, Minoru Terashima, Kusuma Suphakhong, Akihiko Ishimura, Takahisa Takino, Takeshi Suzuki. KDM2B is involved in the epigenetic regulation of TGF-β-induced epithelial-mesenchymal transition in lung and pancreatic cancer cell lines. Journal of Biological Chemistry. 2021. 296. 100213-100213

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MISC (7)：

竹内伸司, 福田康二, 片山量平, 南條成輝, 山田忠明, 鈴木健之, 竹内賢吾, 西尾誠人, 矢野聖二. ALK融合遺伝子陽性肺がんにおける上皮間葉転換によるCrizotinib耐性機構の解明と克服治療の開発. 肺癌. 2016. 56. 6. 552-552
UP Dave, K Akagi, A Dupuy, T Suzuki, NA Jenkins, NG Copeland. Proviral tagging combined with human microarray data reveals genes and pathways that cooperate in disease induction. BLOOD. 2004. 104. 11. 952A-952A
UP Dave, T Suzuki, K Akagi, NA Jenkins, NG Copeland. Lmo2 and Il2rg are frequent targets of retroviral insertion in AKXD T cell leukemias. BLOOD. 2003. 102. 11. 250A-250A
M Yoshida, T Suzuki. HTLV-1 Tax oncoprotein binds to DNA topoisomerase I and inhibits its catalytic activity. LEUKEMIA. 2000. 14. 3. 561-561
T SUZUKI, M YOSHIDA. 2 MECHANISMS OF TRANSCRIPTIONAL ACTIVATION BY HTLV-1 TAX THROUGH NF-KAPPA-B BINDING-SITE. JOURNAL OF CELLULAR BIOCHEMISTRY. 1995. 79-79

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Education (2)：

1988 - 1993 The University of Tokyo
1984 - 1988 The University of Tokyo Faculty of Science Department of Biophysics and Biochemistry

Professional career (1)：

Ph. D. (The University of Tokyo)

Work history (4)：

2007 - 現在金沢大学がん進展制御研究所教授
2003 - 2007 京都大学医学研究科准教授
1999 - 2003 米国国立がん研究所研究員
1993 - 1999 東京大学医科学研究所助手

Association Membership(s) (4)：

日本分子生物学会 , 日本癌学会 , The Molecular Biology Society of Japan , Japanese Cancer Association

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