Rchr
J-GLOBAL ID：200901011246028540   Update date: Mar. 27, 2024

Ishida Tatsuhiro

イシダ タツヒロ | Ishida Tatsuhiro
Affiliation and department：
The University of Tokushima Institute of Health Biosciences The University of Tokushima Graduate School

About The University of Tokushima Institute of Health Biosciences The University of Tokushima Graduate School


Job title： Professor
Homepage URL  (1)： http://www.tokushima-u.ac.jp/ph/faculty/labo/ykz/
Research field  (2)： Pharmaceuticals - chemistry and drug development ,  Pharmaceuticals - analytical and physicochemistry
Research keywords  (7)： 免疫 ,  補体 ,  ガン ,  ターゲティング ,  リポソーム ,  ドラッグデリバリーシステム ,  生物薬剤学
Research theme for competitive and other funds  (71)：
  • 2023 - 2027 イオン液体を用いた中分子医薬品の革新的・非侵襲的吸収促進技術の開発
  • 2023 - 2027 人工高分子PEGに対する生体防御反応の解明と統合的理解
  • 2022 - 2024 脳腫瘍移行性の高い免疫細胞の探索と免疫細胞への薬物搭載による脳腫瘍治療法の開発
  • 2021 - 2024 高活性抗体の誘導を実現する抗原発現エキソソームの脾臓免疫技術基盤の構築
  • 2021 - 2024 Development of albumin DDS carrier based on an understanding of the endogenous albumin transport system
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Papers (227)：
  • Hirai Takeru, Ikeda-Imafuku Mayumi, Tasaka Nanami, Victor Tuan Giam Chuang, Ming Xian, Ishida Tatsuhiro, Akaike Takaaki, Ishima Yu. Human hair keratin responds to oxidative stress via reactive sulfur and supersulfides. Advances in Redox Research. 2024. Vol.10. 100091-100091
  • Sherif A Gaballa, Shimizu Taro, Takata Haruka, ANDO Hidenori, Mohamed Ibrahim, Sherif Emam Abdallah Emam, Matsuo Amorim Cristina Nana, Kim Yuri, Youssef W Naguib, Fatma M Mady, et al. Impact of anti-PEG IgM induced via the topical application of a cosmetic product containing PEG derivatives on the antitumor effects of PEGylated liposomal antitumor drug formulations in mice. Molecular Pharmaceutics. 2024. Vol.21. No.2. 622-632
  • Mayumi Ikeda-Imafuku, Tatsuya Fukuta, Victor Tuan Giam Chuang, Tomohiro Sawa, Toru Maruyama, Masaki Otagiri, Tatsuhiro Ishida, Yu Ishima. Acute Kidney Injury Caused by Rhabdomyolysis Is Ameliorated by Serum Albumin-Based Supersulfide Donors through Antioxidative Pathways. Pharmaceuticals (Basel, Switzerland). 2024. 17. 1
  • Taro Shimizu, Amr S Abu Lila, Yuka Kitayama, Ryo Abe, Haruka Takata, Hidenori Ando, Yu Ishima, Tatsuhiro Ishida. Peritoneal B Cells Play a Role in the Production of Anti-polyethylene Glycol (PEG) IgM against Intravenously Injected siRNA-PEGylated Liposome Complexes. Biological & pharmaceutical bulletin. 2024. 47. 2. 469-477
  • Sakai Hiromi, Kure Tomoko, Kobayashi Naoko, Ito Tadashi, Yamada Yasushi, Yamada Tetsuya, Miyamoto Rina, Imaizumi Takahito, Ando Jiro, Soga Takaomi, et al. Absence of Anaphylactic Reactions to Injection of Hemoglobin-vesicles (Artificial Red Cells) to Rodents. ACS Omega. 2024. Vol.9. No.1. 1904-1915
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MISC (95)：
  • Gaballa Sherif A, Shimizu Taro, ANDO Hidenori, Takata Haruka, Emam Abdallah Emam Sherif, Abdelhameed Mostafa Ramadan Eslam, Naguib Youssef W, Mady Fatma M, Khaled Khaled A, Ishida Tatsuhiro. Treatment-induced and pre-existing anti-PEG antibodies: Prevalence, clinical implications, and future perspectives. Journal of Pharmaceutical Sciences. 2024. Vol.113. No.3. 555-578
  • Ikeda Mayumi, Fukuta Tatsuya, 岩尾 康範, 小田切 優樹, 丸山 徹, Ishida Tatsuhiro, Ishima Yu. 血清アルブミンに存在する超硫黄の解析と創薬応用. Journal of the Pharmaceutical Society of Japan. 2024. Vol.144. No.1. 51-56
  • Shimizu Taro, 濱本 英利, Ishida Tatsuhiro. イオン液体を利用した外用剤・経皮吸収製剤の開発と疾患治療への応用. Drug Delivery System. 2023. Vol.38. No.3. 230-238
  • Mohamed Ibrahim, Abdelhameed Mostafa Ramadan Eslam, Elhewan Ali Emam Elsadek Emam Nehal, Emam Abdallah Emam Sherif, Shimizu Taro, ANDO Hidenori, Ishima Yu, Omar Helmy Elgarhy, Hatem A Sarhan, Amal K Hussein, et al. Polyethylene glycol (PEG): The nature, immunogenicity, and role in the hypersensitivity of PEGylated products. Journal of Controlled Release. 2022. Vol.351. 215-230
  • Matsuo Nana, ANDO Hidenori, Doi Yusuke, Shimizu Taro, Ishima Yu, Ishida Tatsuhiro. The challenge to deliver oxaliplatin (l-OHP) to solid tumors: development of liposomal l-OHP formulations. Chemical & Pharmaceutical Bulletin. 2022. Vol.70. No.5. 351-358
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Patents (6)：
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Books (26)：
  • The Post-insertion Method for the Preparation of PEGylated Liposomes. in Liposomes Methods and Protocols (3rd Edition)
    Springer 2023
  • The Post-insertion Method for the Preparation of PEGylated Liposomes
    Springer 2023
  • 中分子医薬品やDDSに対する免疫応答
    CMC Publishing Co.,Ltd. 2022
  • ナノフィブリル化バクテリアセルロースの生産とその応用
    NTS Inc. 2021
  • タンパクやナノ粒子に対するPEG修飾の有用性と免疫系に与える影響
    Technical Information Institute Co., Ltd. 2021
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Lectures and oral presentations  (746)：
  • 新規hTNFαワクチン製剤の開発を目指した不活化hTNFα誘導体のマウスへの免疫と抗体誘導評価
    (第2回日本抗体学会学術大会 2023)
  • エクソソームの脾臓免疫による抗体誘導評価:ホスト細胞膜表面に対する結合性評価
    (第2回日本抗体学会学術大会 2023)
  • Impact of pre-existing anti-PEG IgM on the mRNA/LNP i.m. vaccination
    (16th International Symposium on Nanomedicine 2023)
  • Role of B cells in antitumor immune responses induced by antigen-loaded hydroxyl PEG-modified liposomes
    (16th International Symposium on Nanomedicine 2023)
  • The molecular weight limitation on increased intestinal absorption by ionic liquids
    (16th International Symposium on Nanomedicine 2023)
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Education (3)：
  • 1995 - 1998 徳島大学 大学院薬学研究科 薬品科学専攻博士後期課程
  • 1993 - 1995 The University of Tokushima
  • 1989 - 1993 The University of Tokushima Faculty of Pharmaceutical Sciences
Professional career (1)：
  • (BLANK) (The University of Tokushima)
Work history (12)：
  • 2018/04 - 現在 徳島大学 産業院研究開発事業部門 教授(兼任)
  • 2015/04 - 現在 徳島大学 大学院医歯薬学研究部(呼称変更) 教授
  • 2014/03 - 現在 The University of Tokushima Faculty of Pharmaceutical Sciences
  • 2014/10 - 2015/09 Tohoku University Frontier Research Institute for Interdisciplinary Sciences
  • 2014/03 - 2015/03 The University of Tokushima Institute of Health Biosciences The University of Tokushima Graduate School
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Committee career (19)：
  • 2020/04 - 現在 日本薬剤学会 理事
  • 2019/04 - 現在 日本薬物動態学会 DISセレクション委員会委員長(DDS DIS)
  • 2018/10 - 現在 日本血液代替物学会 評議員
  • 2018/04 - 現在 日本薬剤学会 広報委員
  • 2017/01 - 現在 Journal of Controlled Release Editorial Board
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Awards (14)：
  • 2023/05/17 - 日本薬剤学会 第17回(2023年度)タケル&アヤ・ヒグチ記念賞
  • 2022/10/15 - Tokushima Prefectural Government 徳島県科学技術大賞 科学技術振興部門
  • 2022/03/25 - The Pharmaceutical Society of Japan The Most Published Author Award 20172021 in Biological and Pharmaceutical Bulletin (BPB)
  • 2022/03/25 - The Pharmaceutical Society of Japan 2021 Highly Cited Review Award for Biological and Pharmaceutical Bulletin (BPB) Liposomal Delivery Systems: Design Optimization and Current Applications
  • 2021/05 - The Pharmaceutical Society of Japan 2020 Highly Cited Review Award for Biological and Pharmaceutical Bulletin (BPB) Liposomal Delivery Systems: Design Optimization and Current Applications
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Association Membership(s) (15)：
Sozai Forum ,  日本核酸医薬学会 ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  日本胃癌学会 ,  American Society of Gene Therapy ,  遺伝子デリバリー研究会 ,  日本癌治療学会 ,  American Association for Cancer Research ,  日本癌学会 ,  日本薬剤学会 ,  日本薬物動態学会 ,  controlled release society ,  日本DDS学会 ,  日本薬学会 ,  日本血液代替物学会
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