Rchr
J-GLOBAL ID：200901012000083271   Update date: Jan. 30, 2024

Fujii Takeshi

フジイ タケシ | Fujii Takeshi
Affiliation and department：
Doshisha Women's College of Liberal Arts Faculty of Pharmaceutical Sciences, Department of Clinical Pharmacy

About Doshisha Women's College of Liberal Arts Faculty of Pharmaceutical Sciences, Department of Clinical Pharmacy


Job title： Professor
Research field  (3)： Pharmacology ,  Pharmaceuticals - health and biochemistry ,  Neuroscience - general
Research keywords  (2)： アセチルコリン ,  Acetylcholine
Research theme for competitive and other funds  (24)：
  • 2022 - 2025 Roles of alpha7 nicotinic acetylcholine receptor in the differentiation of CD8+ T cells
  • 2015 - 2018 Roles of lymphocytic cholinergic system in T cells in regulation of the differentiation of naive T cells via muscarinic acetylcholine receptors
  • 2015 - 2018 Role of SLURP-1, an endogenous alpha7 nicotinic acetylcholine receptor allosteric ligand, in T cell differentiation
  • 2012 - 2015 Investigation on the role of nicotinic acetylcholine receptors in regulation of inflammatory and immune responses
  • 2011 - 2013 Interaction between vacuolar H+ ATPase and lymphocytic cholinergic system in regulation of immune function
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Papers (26)：
  • Masato Mashimo, Koichiro Kawashima, Takeshi Fujii. Non-neuronal Cholinergic Muscarinic Acetylcholine Receptors in the Regulation of Immune Function. Biological & pharmaceutical bulletin. 2022. 45. 6. 675-683
  • Masato Mashimo, Yasuhiro Moriwaki, Hidemi Misawa, Koichiro Kawashima, Takeshi Fujii. Regulation of Immune Functions by Non-Neuronal Acetylcholine (ACh) via Muscarinic and Nicotinic ACh Receptors. International journal of molecular sciences. 2021. 22. 13
  • Takeshi Fujii, Masato Mashimo, Yasuhiro Moriwaki, Hidemi Misawa, Shiro Ono, Kazuhide Horiguchi, Koichiro Kawashima. Expression and Function of the Cholinergic System in Immune Cells. FRONTIERS IN IMMUNOLOGY. 2017. 8. 1085
  • Takeshi Fujii, Masato Mashimo, Yasuhiro Moriwaki, Hidemi Misawa, Shiro Ono, Kazuhide Horiguchi, Koichiro Kawashima. Physiological functions of the cholinergic system in immune cells. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2017. 134. 1. 1-21
  • Masato Mashimo, Yukari Iwasaki, Shoko Inoue, Shoko Saito, Koichiro Kawashima, Takeshi Fujii. Acetylcholine released from T cells regulates intracellular Ca2+, IL-2 secretion and T cell proliferation through nicotinic acetylcholine receptor. Life sciences. 2017. 172. 13-18
ｍore...
MISC (117)：
  • Takeshi Fujii, Yuki Takada-Takatori, Koichiro Kawashima. Basic and clinical aspects of non-neuronal acetylcholine: Expression of an independent, non-neuronal cholinergic system in lymphocytes and its clinical significance in immunotherapy. Journal of Pharmacological Sciences. 2008. 106. 2. 186-192
  • Koichiro Kawashima, Takeshi Fujii. Basic and clinical aspects of non-neuronal acetylcholine: Overview of non-neuronal cholinergic systems and their biological significance. Journal of Pharmacological Sciences. 2008. 106. 2. 167-173
  • T Yamada, T Fujii, T Kanai, T Amo, T Imanaka, H Nishimasu, T Wakagi, H Shoun, M Kamekura, Y Kamagata, et al. Expression of acetylcholine (ACh) and ACh-synthesizing activity in Archaea. LIFE SCIENCES. 2005. 77. 16. 1935-1944
  • K Arimoto, K Fujimoto, T Fujii, K Kawashima. Lymphocytic cholinergic activity in senescence-accelerated mouse (SAM) with immune deficiency. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2005. 97. 231P-231P
  • J Watanabe, T Fujii, K Kawashima. Murine antigen-presenting cells express various subtypes of muscarinic and nicotinic acetylcholine receptor genes. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2005. 97. 231P-231P
ｍore...
Books (6)：
  • Presence of acetylcholine in the blood and its production by choline acetyltransferase in lymphocytes.In Neurochemistry(Teelken, kort eds)
    Plenum 1997
  • Tリンパ球由来アセチルコリンの免疫・神経間相互作用における役割
    リンパ球と神経間シグナリングにおけるキナーゼとホスファターゼ 1997
  • Presence of acetylcholine in the blood and its production by choline acetyltransferase in lymphocytes.In Neurochemistry(Teelken,kort eds)
    Plenum 1997
  • Acetylcholine from T-lymphocytes has a potential role in the regulation of interaction between the immune and Nervous systems.
    Kinases and Phosphatases in Lymphocyte and Neuronal Signaling. Springer 1997
  • デシプラミン長期投与によるラット海馬におけるセロトニン受容体を介するコリン作動性神経伝達の促進
    1996
ｍore...
Works (2)：
  • 羊水・羊膜におけるアセチルコリンの存在
    1999 -
  • Localization of acetylcholine in amniotic cells and fluid
    1999 -
Education (4)：
  • - 1993 Kyoto University
  • - 1993 Kyoto University Graduate School, Division of Pharmaceutical Sciences Pharmacology
  • - 1988 Kyoto University Faculty of Pharmaceutical Sciences
  • - 1988 Kyoto University Faculty of Pharmaceutical Science Pharmaceutical Science/Pharmacology
Professional career (1)：
  • Ph.D. (Kyoto University)
Work history (9)：
  • 2004 - - 共立薬科大学 助教授
  • 2004 - - Kyoritsu College of Pharmacy,
  • 1995 - 2003 Kyoritsu University of Pharmacy
  • 1995 - 2003 Kyoritu College of Pharmacy,
  • 1993 - 1994 共立薬学大学 助手
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Committee career (1)：
  • 日本薬理学会 学術評議員
Awards (4)：
  • 2003 - 第19回日本薬理学会学術奨励賞
  • 2003 - 19th Young Investigator Award of the Japanese Pharmacological Society
  • 2000 - 第6回JJP 優秀論文賞
  • 2000 - 6<sup>th</sup> the JJP Prize
Association Membership(s) (3)：
日本薬学会 ,  日本神経科学学会 ,  日本薬理学会
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