Matsumoto Mitsuyo

マツモトミツヨ | Matsumoto Mitsuyo

Affiliation and department：

Research field (2)： Molecular biology , Tumor biology

Research keywords (4)：微小環境 , 転写因子 , がん , Environmental and Biological Chemistry

Research theme for competitive and other funds (8)：

2022 - 2026 転写因子BACH1と鉄による膵臓癌上皮間葉転換と幹細胞性の促進機構の解明
2020 - 2025 Development of anti-cancer strategy by exploiting BACH1 addiction
2019 - 2022 The study of malignant transformation and vulnerability of mutated-RAS carcinomas defined by epithelial-mesenchymal transition and susceptibility to ferroptosis
2017 - 2019 Identification of the mechanism by which SAM synthesis inhibition induces erythroblast maturation
2016 - 2019 The effect of BACH1 on malignant transformation of tumor

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Papers (44)：

Riko Irikura, Hironari Nishizawa, Kazuma Nakajima, Mie Yamanaka, Guan Chen, Kozo Tanaka, Masafumi Onodera, Mitsuyo Matsumoto, Kazuhiko Igarashi. Ferroptosis model system by the re-expression of BACH1. Journal of biochemistry. 2023
Masatoshi Ikeda, Hiroki Kato, Hiroki Shima, Mitsuyo Matsumoto, Eijiro Furukawa, Yan Yan, Ruiqi Liao, Jian Xu, Akihiko Muto, Tohru Fujiwara, et al. Heme-dependent induction of mitophagy program during differentiation of murine erythroid cells. Experimental hematology. 2022. 118. 21-30
Liang Liu, Mitsuyo Matsumoto, Miki Matsui-Watanabe, Kyoko Ochiai, Bert K K Callens, Long Chi Nguyen, Yushi Kozuki, Miho Tanaka, Hironari Nishizawa, Kazuhiko Igarashi. BACH1 Expression Is Promoted by Tank Binding Kinase 1 (TBK1) in Pancreatic Cancer Cells to Increase Iron and Reduce the Expression of E-Cadherin. Antioxidants (Basel, Switzerland). 2022. 11. 8
Mahabub Alam, Hiroki Shima, Yoshitaka Matsuo, Nguyen Chi Long, Mitsuyo Matsumoto, Yusho Ishii, Nichika Sato, Takato Sugiyama, Risa Nobuta, Satoshi Hashimoto, et al. mTORC1-independent translation control in mammalian cells by methionine adenosyltransferase 2A and S-adenosylmethionine. The Journal of biological chemistry. 2022. 298. 7. 102084-102084
Manuj Ahuja, Navneet Ammal Kaidery, Otis C Attucks, Erin McDade, Dmitry M Hushpulian, Arsen Gaisin, Irina Gaisina, Young Hoon Ahn, Sergey Nikulin, Andrey Poloznikov, et al. Bach1 derepression is neuroprotective in a mouse model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 2021. 118. 45

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MISC (56)：

松本光代, 五十嵐和彦. BACH1による膵臓癌細胞の細胞内自由鉄の増加は上皮間葉移行に影響する(BACH1 promotes epithelial-mesenchymal transition by enhancing cellular labile iron level in pancreatic cancer cell). 日本癌学会総会記事. 2022. 81回. P-3144
Mahabub Alam, Shima Hiroki, Nguyen Long C., Matsumoto Mitsuyo, Sugiyama Takato, Nobuta Risa, Hashimoto Satoshi, Matsuo Yoshitaka, Inada Toshifumi, Igarashi Kazuhiko. メチオニンアデノシルトランスフェラーゼ2Aによる哺乳類細胞のmTORC1非依存的な翻訳制御機構(mTORC1-independent translational regulation of mammalian cells by methionine adenosyltransferase 2A). 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [2T15a-666)]
中嶋一真, 西澤弘成, 成川礼, 松本光代, 五十嵐和彦. ビリベルジン結合型シアノバクテリオクロムを用いたフェロトーシス高感受性細胞の検出. 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [P-498]
西澤弘成, 松本光代, 五十嵐和彦. 転写因子BACH1が活性化するフェロトーシス細胞由来抗老化シグナルモデル. 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [2T13a-487)]
加藤浩貴, Long Nugyen, 石井悠翔, 松本光代, 三枝大輔, 舟山亮, 岡江寛明, 藤原亨, 武藤哲彦, 中山啓子, et al. 幹細胞から赤血球への通り道メチオニン代謝によるエピゲノム調節をかいした赤血球造血制御(Methionine metabolism controls erythropoiesis by epigenetic regulation). 日本血液学会学術集会. 2021. 83回. PSY-4

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Books (1)：

Biosynthesis and Action of Estrogen in Gynecological Cancers
Research Signpost, India 2007

Professional career (1)：

農学博士

Work history (6)：

2014 - 現在 Tohoku University Graduate School of Medicine
2012 - Tohoku University Tohoku Medical Megabank Organization
2010 - 東北大学大学院医学系研究科助教
2008 - がん集学的治療財団若手研究員
2006 - Tohoku University Graduate School of Medicine

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