Research theme for competitive and other funds (12)：
2017 - 2020 Elucidation of the mechanism of physiological ER stress response required for the homeostasis of cell and whole body
2012 - 2017 The molecular mechanism of ER stress response and the pathophysiology of ER stress disorders
2007 - 2012 Analyses of the physiological roles of unfolded protein response
2002 - 2006 ER Stress-sensing system and Analyses of its signal transduction mechanism.
2003 - 2004 In vivo functions of the endoribonuclease Ire1
2003 - 2004 ストレス応答性RNaseであるIre1と標的RNAのユニークな動態
2002 - 2004 Sensing mechanism of IRE1 to abnormal proteins
2002 - 2002 小胞体ストレス応答性RNaseであるIre1と標的RNAのユニークな動態
2001 - 2002 Functional analyses of ER stress sensor proteins
1995 - 1996 Functional analyzes of molecular chaperons concerning on protein translocation across the ER membrane
小胞体ストレス応答機構に関する研究
Mechanism of endoplasmic reticulum stress response
Show all
Papers (14)：
Ashuei Sogawa, Ryota Komori, Kota Yanagitani, Miku Ohfurudono, Akio Tsuru, Koji Kadoi, Yukio Kimata, Hiderou Yoshida, Kenji Kohno. Signal sequence-triage is activated by translocon obstruction sensed by an ER stress sensor IRE1α. Cell structure and function. 2023. 48. 2. 211-221
Fujimoto T, Nakamura O, Saito M, Tsuru A, Matsumoto M, Kohno K, Inaba K, Kadokura H. Identification of the physiological substrates of PDIp, a pancreas-specific protein disulfide isomerase family member. Journal of Biological Chemistry. 2018. 293. 48. 18421-18433
Mechanism of the production of small dense LIX(sLDC) in hyper triglyceridemia
Athelosclerosis 1998
Mechanism of the production of small dense LIX(sLDC) in hyper triglyceridemia
Athelosclerosis 1998
Lectures and oral presentations (2)：
PERK-ATF4 branch of the unfolded protein response is required for the full activation of IRE1α-XBP1 signaling
(FASEB Science Research Conferences 2015)
