Takahashi Naoto

タカハシナオト | Takahashi Naoto

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Hematology and oncology

Research keywords (6)：薬物遺伝学 , 薬物動態 , 分子細胞遺伝学 , 血液腫瘍学 , 血液学 , hematological malignancy

Research theme for competitive and other funds (13)：

2018 - 2022 The mechanism of organelle relocation in human erythroblasts.
2014 - 2018 Do patients taking tacrolimus need to undergo CYP3A5 genotyping along with blood concentration monitoring?
2014 - 2017 Therapeutic drug management of the novel agents for multiple myeloma
2014 - 2017 Development of a new treatment strategy using TDM for next generation anticancer drug
2013 - 2016 Identification of microRNAs that might be therapeutic target of malignant lymphomas

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Papers (304)：

Nagi Tozawa, Takaya Yamashita, Miho Nara, Yuki Fujioka, Sho Ikeda, Takahiro Kobayashi, Isuzu Kobayashi, Akihiro Kitadate, Yoshihiro Kameoka, Naoto Takahashi. Ponatinib Improved the Prognosis of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: A Japanese Single-Center Cohort Study. Cureus. 2023. 15. 12. e50416
Naoki Osada, Jiro Kikuchi, Hidekatsu Iha, Hiroshi Yasui, Sho Ikeda, Naoto Takahashi, Yusuke Furukawa. c-FOS is an integral component of the IKZF1 transactivator complex and mediates lenalidomide resistance in multiple myeloma. Clinical and Translational Medicine. 2023. 13. 8
Hajime Kaga, Hirotoshi Matsumura, Ayano Saito, Masaya Saito, Fumito Abe, Takehiro Suzuki, Naoshi Dohmae, Masafumi Odaka, Atsushi Komatsuda, Hideki Wakui, et al. Comparative proteomic analysis of glomerular proteins in IgA nephropathy and IgA vasculitis with nephritis. Clinical Proteomics. 2023. 20. 1
Kazuaki Kameda, Ryo Yanagiya, Yuji Miyatake, Joaquim Carreras, Hiroshi Higuchi, Hiromichi Murayama, Takashi Ishida, Asahi Ito, Shinsuke Iida, Noriko Fukuhara, et al. Hepatic niche leads to aggressive natural killer cell leukemia proliferation through transferrin-transferrin receptor 1 axis. Blood Journal. 2023
金澤達郎, 齋藤雅也, 齋藤綾乃, 阿部史人, 加賀一, 高橋直人. 保存期CKDにおけるESA初期治療抵抗性と予後に関する検討. 日本腎臓学会誌. 2023. 65. 3. 294-294

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MISC (110)：

齊藤由紀子, 小林敬宏, 小林敬宏, 鎌田幸子, 亀岡吉弘, 菊地優子, 永沼綾子, 富谷陽子, 高橋直人, 嵯峨知生, et al. 有毛細胞白血病を疑うリンパ球増多症で発症し,細胞表面解析から診断に至った慢性NK細胞増多症の一例. 日本検査血液学会雑誌. 2021. 22
池田翔, 阿部史人, 北舘明宏, 高橋直人, 田川博之. ヘキソキナーゼ-2は低酸素誘導性オートファジーを促進し、多発性骨髄腫のプロテアソーム阻害薬抵抗性を誘導する(Hexokinase-2(HK2) promotes hypoxia-inducible autophagy, leading to proteasome inhibitor resistance in multiple myeloma). 日本癌学会総会記事. 2019. 78回. J-1016
Makoto Hirokawa, Naohito Fujishima, Masaru Togashi, Akiko Saga, Ayumi Omokawa, Tomoo Saga, Yuki Moritoki, Shigeharu Ueki, Naoto Takahashi, Kazutaka Kitaura, et al. High-throughput sequencing of IgG B-cell receptors reveals frequent usage of the rearranged IGHV4-28/IGHJ4 gene in primary immune thrombocytopenia. Scientific reports. 2019. 9. 1. 8645-8645
福地峰世, 植木重治, 山本洋平, 奈良美保, 今野泰典, 面川歩, 嵯峨知生, 守時由起, 大森泰文, 高橋直人, et al. 好酸球増多疾患・好酸球性肺炎著明な組織内シャルコー・ライデン結晶を認めた好酸球増多症候群患者. アレルギー. 2019. 68. 4-5. 529-529
福地峰世, 植木重治, 山本洋平, 奈良美保, 今野泰典, 面川歩, 嵯峨知生, 守時由起, 大森泰文, 高橋直人, et al. 好酸球増多疾患・好酸球性肺炎著明な組織内シャルコー・ライデン結晶を認めた好酸球増多症候群患者. アレルギー. 2019. 68. 4-5. 529-529

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Education (4)：

- 1997 Akita University
- 1997 Akita University Graduate School, Division of Medicine internal medicine
- 1990 Akita University School of Medicine School of Medicine
- 1990 Akita University Faculty of Medicine

Professional career (1)：

Doctor of medical science (Akita University)

Work history (7)：

2015/02 - 現在 Akita University Graduate School of Medicine
2006/02 - 2015/01 - 秋田大学医学部第三内科学講座講師
2005/09 - 2006/01 Akita University School of Medicine
2003/05 - 2005/08 カナダサスカチュワン大学がんセンター研究員
2002/03 - 2003/04 Akita University School of Medicine

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Committee career (3)：

日本血液学会血液専門医血液指導医評議員
日本内科学会総合内科専門医
The Japanese Society of Internal Medicine FJSIM

Awards (2)：

2001 - 山下太郎学術研究奨励賞
1999 - 第10回秋田医学学術奨励賞

Association Membership(s) (5)：

米国血液学会 , 日本血液学会 , 日本内科学会 , The Japanese Society of Hematology , The Japanese Society of Internal Medicine

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