Rchr
J-GLOBAL ID：200901013385455120
Update date: Apr. 23, 2024
Horiuchi Hiroyuki
ホリウチ ヒロユキ | Horiuchi Hiroyuki
Affiliation and department：
Job title：
教授
Research field (2)：
Laboratory animal science
, Animals: biochemistry, physiology, behavioral science
Research keywords (9)：
dementia
, genome editing
, germ cell
, pluripotent stem cell
, embryonic stem cells
, membrane protein
, Cytokine
, thrombocyte
, chicken
Research theme for competitive and other funds (14)：
- 2022 - 2031 Bio-Digital Transformation (バイオDX)産学共創拠点研究課題3家禽のデジタル育種とバイオ医薬品製造技術の開発
- 2022 - 2026 ニワトリ・ウズラリソースの収集・保存・提供
- 2020 - 2023 Comprehensive identification of responsible regulatory molecules that define the seizure periodicity and inflammatory diversity of autoinflammatory diseases
- 2019 - 2022 ニワトリの雌雄産み分けは可能か?ー鳥類性決定機構の解析を通してー
- 2019 - 2021 鳥類のゲノム編集・自由自在
- 2013 - 2016 Conservation of Onagadori designated as a special natural treasure of Japan by developmental engineering
- 2013 - 2016 Development of genome editing technology in birds
- 2007 - 2009 Basic and Applied Study on Chicken Embryonic Stem Cell Lines
- 2004 - 2005 Establishment of chicken transgenic technology using embryonic stem cells.
- 2000 - 2001 リコビナントgp130を用いたニワトリIL6とLIFのクローニング
- 1999 - 2000 Analysis of T cell selection in the germinal center
- 1996 - 1996 ニワトリ栓球由来細胞増殖因子の遺伝子解析
- 1995 - 1995 ニワトリ型単クローン抗体を用いた主要組織適合(MHC)遺伝子の解析
- 1994 - 1994 ニワトリ型単クローン抗体を用いた主要組織適合(MHC)遺伝子の解析
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Papers (90)：
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Toshiaki Nonaka, Yasushi Iwasaki, Hiroyuki Horiuchi, Katsuya Satoh. Detection limitations of prion seeding activities in blood samples from patients with sporadic prion disease. BMC Neurology. 2024. Open Access. Open Access. Open Access-Open Access
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Tenkai Watanabe, Takumi Terada, Ryo Ezaki, Mei Matsuzaki, Syuichi Furusawa, Hiroyuki Horiuchi. Chicken Interleukin-5 is Expressed in Splenic Lymphocytes and Affects Antigen-Specific Antibody Production. Journal of Poultry Science, 61, j. 2024. 61. jpsa2024002. on line-on line
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Ryota Kajihara, Ryo Ezaki, Kennosuke Ichikawa, Tenkai Watanabe, Takumi Terada, Mei Matsuzaki, Hiroyuki Horiuchi. Wnt signaling blockade is essential for maintaining the pluripotencyof chicken embryonic stem cells. Poultry Science. 2023. open access. open access. open access-open access
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Ryota Kajihara, Ryo Ezaki, Tenkai Watanabe, Kennosuke Ichikawa, Mei Matsuzaki, Hiroyuki Horiuchi. Evaluation of expression systems for recombinant protein production in chicken egg bioreactors. Biotechnology Journal. 2023
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Tenkai Watanabe, Yuta Ochi, Ryota Kajihara, Kennosuke Ichikawa, Ryo Ezaki, Mei Matsuzaki, Hiroyuki Horiuchi. Lipofection with LipofectamineTM 2000 in a heparin-free growth medium results in high transfection efficiency in chicken primordial germ cells. Biotechnology Journal. 2023
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MISC (2)：
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Mikiharu Nakano, Masaki Nishimoto, Ryo Ezaki, Shuichi Furusawa, Hiroyuki Horiuchi. Germ line competency of chicken embryonic stem cells to produce genetically modified chickens. TRANSGENIC RESEARCH. 2011. 20. 5. 1160-1160
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Nikiharu Nakano, Yuji Fukushima, Kenjiro Arisawa, Masaki Nishimoto, Ryo Ezaki, Shuichi Furusawa, Haruo Matsuda, Hiroyuki Horiuchi. Establishment of novel chicken embryonic stem cells capable of differentiating into germ cells. DEVELOPMENTAL BIOLOGY. 2010. 344. 1. 523-523
Patents (18)：
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鳥類,鳥類の作出方法および鳥類の卵
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ニワトリ胚性幹細胞およびその評価方法
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ニワトリ胚性幹細胞およびその評価方法
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ニワトリ胚性幹細胞およびその評価方法
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ニワトリキメラ抗体およびその利用
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Books (18)：
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広島経済レポート
株式会社 広島経済研究会 2024
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明日の食品産業2024 1・2
食品産業センター 2024
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ゲノム編集の最新技術と医薬品・遺伝子治療・農業・水畜産物・有用物質生産への活用
情報技術協会 2023 ISBN:9784861049781
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ゲノム編集の最新技術と医薬品・遺伝子治療・農業・水畜産物・有用物質生産への活用
技術情報協会 2023 ISBN:9784861049781
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ゲノム編集技術~実験上のポイント/産業利用に向けた研究開発動向と安全性周知
株式会社 情報機構 2023 ISBN:9784865022421
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Lectures and oral presentations (80)：
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低アレルゲン鶏卵の作出と安全性評価について
(SFSS食のリスコミフォーラム第1回 2024)
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Effects of Wnt signaling regulation on chicken embryonic stem cells
(The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
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Effect of cell cycle regulation on genome editing efficiency in chicken cells
(The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
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Transfection and genome editing in chicken primordial germ cells
(The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
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Toward building digital breeding in poultry
(The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
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Education (4)：
- 1988 - 1990 Hiroshima University Graduate School, Division of Biophere Sciences
- 1988 - 1990 Hiroshima University Graduate School, Division of Biophere Sciences
- 1983 - 1988 Hiroshima University Faculty of Applied Biological Science
- 1983 - 1988 Hiroshima University Faculty of Applied Biological Science
Professional career (1)：
- Doctor of Science (Hiroshima University)
Work history (4)：
- 2012/05/01 - Hiroshima University professor
- 2010/04/01 - 2012/04/30 Hiroshima University associate professor
- 2007/04/01 - 2010/03/31 Hiroshima University Graduate School of Biosphere Science Research associate
- 1992/01/01 - 2002/03/31 Hiroshima University Faculty of Applied Biological Science Research Assistant
Awards (9)：
- 2023/12/01 - Japanese Association for Animal Cell Technology JAACT2023 Oral Awardee Somatic Differentiation of Chicken Primordial Germ Cells Exhibits Partial Epithelial-to-Mesenchymal Transition (EMT)-like Features
- 2022/03/17 - 日本養豚学会 若手優秀発表賞 豚サーコウイルス2型(PCV2)の検出法に 関する研究
- 2021/12/04 - 鳥類内分泌研究会 第45回鳥類内分泌研究会 ニワトリPGCsにおける遺伝子工学的な特徴
- 2021/03/27 - 日本家禽学会 優秀発表賞 アヒル RIG-I ノックイン DF-1 細胞における, 自然免疫応答の解析
- 2016/12/01 - The 39th Annual Meeting of the Molecular Biology Society of Japan, Best Poster Award Are chicken epiblast-derived stem cells naïve or primed pluripotent state?
- 2016/12/01 - The Molecular Biology Society of Japan The 39th Annual Meeting of the Molecular Biology Society of Japan, Best Poster Award Are chicken epiblast-derived stem cells naive or primed pluripotent state?
- 2015/12/03 - BMB2015 Young-Scientist Presentation Award Study on male sex determination gene in the chicken using genome editing technology
- 2015/12/03 - The Molecular Biology Society of Japan, Japanese Biochemical Society BMB2015 Young-Scientist Presentation Award Study on male sex determination gene in the chicken using genome editing technology
- 2011/10/26 - Dr. Lluis Montoliu ISTT Executive Committee, President 10th Transgenic Technology (TT) meeting,Best Poster Award
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Association Membership(s) (2)：
The Japanease Society for Genome Editing
, The Molecular Biology Society of Japan
