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J-GLOBAL ID：200901013677184658   Update date: Mar. 07, 2024

Chatani Eri

チャタニ エリ | Chatani Eri
Affiliation and department：
Kobe University Graduate School of Science Division of Chemistry

About Kobe University Graduate School of Science Division of Chemistry


Job title： Associate Professor
Research field  (2)： Biophysics ,  Structural biochemistry
Research keywords  (13)： protein structures ,  aggregation ,  amyloid fibrils ,  misfolding ,  folding ,  Proteins ,  機能 ,  立体構造 ,  凝集 ,  アミロイド線維 ,  ミスフォールディング ,  フォールディング ,  タンパク質
Research theme for competitive and other funds  (13)：
  • 2022 - 2026 液液相分離中アミロイド生成の定量的解析法の確立
  • 2020 - 2024 アミロイド核生成を誘起するタンパク質集合動態の解明
  • 2020 - 2023 病態診断を指向したアミロイド構造多形の簡便かつ迅速な評価法の構築
  • 2017 - 2022 Mechanism and regulation of protein aggregation in complicated cellular systems
  • 2018 - 2021 Biochemical study of maintenance DNA methylation regulated by histone modification(s)
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Papers (72)：
  • Shohei Maekawa, Keisuke Yuzu, Eri Chatani, Kenichi Morigaki. Oligomerization and aggregation of NAP-22 with several metal ions. Neuroscience letters. 2024. 821. 137623-137623
  • Keisuke Yuzu, Hiroshi Imamura, Takuro Nozaki, Yuki Fujii, Shaymaa Mohamed Mohamed Badawy, Ken Morishima, Aya Okuda, Rintaro Inoue, Masaaki Sugiyama, Eri Chatani. Mechanistic modeling of amyloid oligomer and protofibril formation in bovine insulin. Journal of Molecular Biology. 2024. 168461-168461
  • Minami Kurokawa, Tomoya Ohtsu, Eri Chatani, Atsuo Tamura. Hyper Thermostability and Liquid-Crystal-Like Properties of Designed α-Helical Peptide Nanofibers. The journal of physical chemistry. B. 2023. 127. 39. 8331-8343
  • Po-Wei Yi, Wei-Hsiang Chiu, Shuichi Toyouchi, Roger Bresoli-Obach, Johan Hofkens, Eri Chatani, Yoichiroh Hosokawa, Teruki Sugiyama, Hiroshi Masuhara. Two-stage optical trapping and assembling of protein at air/solution interface. Appl. Phys. Express. 2023. 16. 25501
  • Mao Fukuyama, Suguru Nishinami, Yoko Maruyama, Taiki Ozawa, Shunsuke Tomita, Yumiko Ohhashi, Motohiro Kasuya, Masao Gen, Eri Chatani, Kentaro Shiraki, et al. Detection of Fibril Nucleation in Micrometer-Sized Protein Condensates and Suppression of Sup35NM Fibril Nucleation by Liquid-Liquid Phase Separation. Analytical Chemistry. 2023
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MISC (6)：
  • Yanagi Kotaro, Sakurai Kazumasa, Chatani Eri, Naiki Hironobu, Goto Yuji. 3P-010 Analysis of the amyloid fiber extension mechanism using H/D exchange(The 46th Annual Meeting of the Biophysical Society of Japan). Seibutsu Butsuri. 2008. 48. S129
  • Chatani Eri, Onishi Reina, Konuma Tsuyoshi, Sakurai Kazumasa, Naiki Hironobu, Goto Yuji. 2P-083 Monitoring the fibrillation intermediate of β2-microglobulin by Trp fluorescence and H/D exchange-NMR(The 46th Annual Meeting of the Biophysical Society of Japan). Seibutsu Butsuri. 2008. 48. S88
  • Saeka Miwako, Todokoro Yasuto, Egawa Ayako, Kameda Atsushi, Chatani Eri, Yagi Hisashi, Akutsu Hideo, Naiki Hironobu, Fujiwara Toshimichi, Goto Yuji. 2P-008 Structural Analysis of Amyloid Fibrils of β2-Microglobulin by Solid-State NMR(The 46th Annual Meeting of the Biophysical Society of Japan). Seibutsu Butsuri. 2008. 48. S76
  • Chatani Eri, Adachi Rumi, Sakai Miyo, Naiki Hironobu, Goto Yuji. 3P055 Uniforming the Molecular Weigh of Amyloid Fibrils by Ultrasonication(Proteins-stability, folding, and other physicochemical properties,Oral Presentations). Seibutsu Butsuri. 2007. 47. S216
  • Sakata Michiko, Chatani Eri, Kameda Atsushi, Sakurai Kazumasa, Naiki Hironobu, Goto Yuji. 2P109 Folding and Unfolding Kinetics of β2-Microglobulin as Probed by Tryptophan Fluorescence(31. Protein folding and misfolding (II),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006). Seibutsu Butsuri. 2006. 46. 2. S323
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Books (1)：
  • 高圧力下の生物科学
    さんえい出版 2006 ISBN:4915592812
Lectures and oral presentations  (269)：
  • Two-stage optical trapping mechanism of protein at its air/solution interface
    (第70回応用物理学会春季学術講演会 2023)
  • "アミロイド前凝集体を標的とした 分子シャペロンαB-クリスタリンの線維形成阻害様式"
    (第14回 タンパク質の異常凝集と その防御・修復機構に関する研究会 2023)
  • アミロイド核形成段階におけるオリゴマーおよびプロトフィブリルの形成機構
    (第14回 タンパク質の異常凝集と その防御・修復機構に関する研究会 2023)
  • アミロイド線維の核形成メカニズムの解明
    (第14回ナノ・マイクロ計測化学セミナー 2023)
  • Study of oligomer and protofibril mediated amyloid nucleation: Mechanistic insights from insulin and its B chain
    (JSPS Core to Core Program and Technical University of Munich Joint Meeting: Amyloid Symposium Munich 2023 2023)
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Education (3)：
  • 1999 - 2002 Kyoto University Graduate School of Agriculture Department of Applied Life Sciences
  • 1997 - 1999 Kyoto University Graduate School of Agriculture Department of Applied Life Sciences
  • 1993 - 1997 Kyoto University Faculty of Agriculture Department of Agricultural Chemistry
Professional career (2)：
  • 修士(農学) (京都大学)
  • 博士(農学) (京都大学)
Work history (6)：
  • 2011/04 - 現在 Department of Chemistry, Graduate School of Science, Kobe University Associate Professor
  • 2008/04 - 2011/03 Ritsumeikan University College of Pharmaceutical Sciences, Department of Pharmacy Assistant Professor
  • 2006/04 - 2008/03 大阪大学蛋白質研究所 特任研究員
  • 2003/04 - 2006/03 日本学術振興会特別研究員(PD)
  • 2002/04 - 2003/03 京都大学農学部教務補助
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Awards (10)：
  • 2023/11 - 第61回日本生物物理学会 学生発表賞
  • 2022/05 - 化学とマイクロ・ナノシステム学会第45回研究会 優秀研究賞 液液相分離相からのアミロイド形成速度のサイズ依存性
  • 2020/08 - 日本生化学会 第93回日本生化学会大会 若手優秀発表賞
  • 2016/10 - 新学術領域「動的秩序と生体機能」 第3回「動的秩序と機能」若手研究会 優秀ポスター賞 線維前駆中間体に作用点をもつフィブリノーゲンのアミロイド線維化阻害機構
  • 2016/05 - 日本生化学会近畿支部 平成28年度日本生化学会近畿支部奨励賞 Exploring the molecular basis of self-propagation of amyloid fibrils and its manifestation through the observation of prefibrillar species
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Association Membership(s) (3)：
日本生化学会 ,  日本生物物理学会 ,  日本蛋白質科学会
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