Rchr
J-GLOBAL ID：200901014121721596
Update date: Jan. 30, 2024
Hashimoto Noriyoshi
ハシモト ノリヨシ | Hashimoto Noriyoshi
Affiliation and department：
Research field (1)：
Laboratory animal science
Research keywords (8)：
実験動物学
, KSマウス
, 胚移植用レシピエントマウス
, legumain
, asparaginyl transferase
, Glycosyltransferase
, Knockout mice
, Pathological Model
Research theme for competitive and other funds (25)：
- 2018 - 2021 Development of new albino inbred strain mice for embryo-transfer recipient
- 2011 - 2013 Identification of novel homing molecules of hematopoietic stem cells and development of efficient bone marrow transfer methods by modifying carbohydrates
- 2009 - 2011 Characterization of AEP/Legumain-deficient mice as a new model of lysosome disease
- 2006 - 2011 アスパラギンエンドペプチダーゼ欠損による血球貪食症候群様病態の解析
- 2006 - 2011 Analysis of Hemophagocytic syndrome like disease in legumain deficient mice
- 2007 - 2009 Development of mouse models for human diseases caused by impaired glycosylation and analysis of their mechanisms
- 2006 - 2008 Characterization of AEP/Legumain-deficient mice as a model of hemophagocytic syndrome-like disease
- 2005 - 2006 β4-ガラクトース転移酵素-I欠損によるIga腎症発症機構の解析
- 2004 - 2004 自己免疫疾患におけるアスパラギンエンドペプチダーゼによる免疫記憶の調節
- 2003 - 2004 ORC4変異マウスを用いた個体レベルでの細胞周期研究
- 2003 - 2004 Functional analysis of carbohydrate antigens in chemically induced tumor cells derived from beta-1,4-galactosyltransferase-I knockout mice
- 2004 - アスパラギンエンドペプチダーゼの免疫系での機能解析
- 2002 - 2003 改良遺伝子トラップ法による新規発生制御遺伝子の単離と機能解析
- 2001 - 2003 Elucidation of individual roles of the galactosyl|ransferase gene family using gene knockout mice
- 2001 - 2001 糖転移酵素遺伝子欠損マウスを用いた発癌・転移における糖鎖機能の解析
- 2001 - 2001 改良遺伝子トラップ法による新規発生制御遺伝子の単離と機能解析
- 2000 - 2000 糖転移酵素遺伝子欠損マウスを用いた発癌・転移における糖鎖機能の解析
- 2000 - 2000 ガラクトース転移酵素遺伝子ノックアウトマウスを用いた糖鎖機能の解析
- 1998 - 2000 Functional analysis of IL-1 in immune and stress responses using gene knockout mice
- 2000 - 癌の浸潤と転移における糖鎖機能の役割
- 1999 - 1999 ガラクトース転移酵素遺伝子ノックアウトマウスを用いた糖鎖機能の解析
- 1997 - 1998 カルニチン欠乏症(JVS)マウスの病態発生に及ぼす環境ストレスの影響
- 1996 - 1997 Evaluation of disease model traits in cultured cells derived from carnitine deficient JVS mice
- 1995 - 1995 免疫担当細胞の分化研究モデルとしてのLeaky SCIDマウスの確立
- 1991 - 1993 Characterization of mice carrying multiple mutant genes which cause the different immunological defects.
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Papers (9)：
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Soichiro Takagaki, Rieko Yamashita, Noriyoshi Hashimoto, Kazushi Sugihara, Kanako Kanari, Keisuke Tabata, Toshikazu Nishie, Shogo Oka, Masanori Miyanishi, Chie Naruse, et al. Galactosyl carbohydrate residues on hematopoietic stem/progenitor cells are essential for homing and engraftment to the bone marrow. Scientific reports. 2019. 9. 1. 7133-7133
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N. Hashimoto, S. Shimoda, H. Kawanaka, K. Tsuneyama, H. Uehara, T. Akahoshi, N. Kinjo, A. Taketomi, K. Shirabe, K. Akashi, et al. Modulation of CD4(+) T cell responses following splenectomy in hepatitis C virus-related liver cirrhosis. CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2011. 165. 2. 243-250
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山本 靖彦, 土井 俊夫, 加藤 一郎, 櫻井 繁, 米倉 秀人, 渡辺 琢夫, Myint Khin Mar, 原島 愛, 高澤 伸, 岡本 宏, et al. 糖尿病腎症におけるRAGEの役割の解明 RAGEノックアウトマウス(RAGE-/-)を用いて. 糖尿病. 2004. 47. Suppl.1. S177-S177
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大成 亜希, 木戸 康人, 加々美 徹, 崔 吉道, 二階堂 浩子, 橋本 憲佳, 浅野 雅秀, 玉井 郁巳, 辻 彰. 血液脳関門におけるカルニチン/有機カチオントランスポーターOCTN2の機能発現. 薬物動態. 2000. 15. Suppl. S164-S164
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山口 佳一, 崔 吉道, 玉井 郁巳, 辻 彰, 橋本 憲佳, 二階堂 浩子. jvsマウスを用いた有機カチオン性物質の体内動態変動解析. 日本薬学会年会要旨集. 2000. 120年会. 4. 58-58
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MISC (44)：
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Hemophagocytic syndrome-like disorders in asparaginyl endopeptidase-deficient mice. 2011. 63. 6. 634-639
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Chi-Bun Chan, Michiyo Abe, Noriyoshi Hashimoto, Chunhai Hao, Ifor R. Williams, Xia Liu, Shinji Nakao, Akitsugu Yamamoto, Chengyun Zheng, Jan-Inge Henter, et al. Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome (vol 106, pg 468, 2008). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009. 106. 14. 6023-6023
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Chi-Bun Chan, Michiyo Abe, Noriyoshi Hashimoto, Chunhai Hao, Ifor R. Williams, Xia Liu, Shinji Nakao, Akitsugu Yamamoto, Shi-Yong Li, Ikuko Hara-Nishimura, et al. Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009. 106. 2. 468-473
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Chi-Bun Chan, Michiyo Abe, Noriyoshi Hashimoto, Chunhai Hao, Ifor R. Williams, Xia Liu, Shinji Nakao, Akitsugu Yamamoto, Shi-Yong Li, Ikuko Hara-Nishimura, et al. Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009. 106. 2. 468-473
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Toshikazu Nishie, Osamu Miyaishi, Haruhito Azuma, Akihiko Kameyama, Chile Naruse, Noriyoshi Hashimoto, Hitoshi Yokoyama, Hisashi Narimatsu, Takashi Wada, Masahide Asano. Development of immunoglobulin A nephropathy-like disease in beta-1,4-galactosyltransferase-I-deficient mice. AMERICAN JOURNAL OF PATHOLOGY. 2007. 170. 2. 447-456
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Education (4)：
- - 1992 Hokkaido University
- - 1992 Hokkaido University Graduate School, Division of Veterinary Medicine
- - 1987 Hokkaido University School of Veterinary Medicine Veterinary Medicine
- - 1987 Hokkaido University Faculty of Veterinary Medicine
Professional career (1)：
Work history (4)：
- 1992 - 2003 : 金沢大学 助手
- 1992 - 2003 : Kanazawa University
- 2003 - -: 金沢大学 准教授
- 2003 - -: Kanazawa University
Awards (1)：
Association Membership(s) (3)：
日本獣医学会
, 日本実験動物医学会
, 日本実験動物学会
