Rchr
J-GLOBAL ID：200901014133180493
Update date: Feb. 01, 2024
Yukitake Hideharu
ユキタケ ヒデハル | Yukitake Hideharu
Affiliation and department：
Job title：
Others(describe your title)
Research field (1)：
Oral medicine
Research theme for competitive and other funds (11)：
- 2022 - 2025 歯周病原細菌の9型分泌機構における選択的分泌メカニズムの解明
- 2022 - 2025 歯周病原細菌などのバクテロイディア綱細菌固有のリポタンパク質輸送機構の解明
- 2020 - 2023 Elucidation of feedback regulation of the expression of the type IX secretion system (T9SS) of Porphyromonas gingivalis
- 2019 - 2022 Function of a novel Rab protein in neutrophils and its role in periodontal disease
- 2016 - 2018 Elucidation of cascade regulation by two different control systems of the type IX secretion system
- 2013 - 2016 Supermolecule structure and mechanism of a novel bacterial protein secretion system, type IX secretion system
- 2013 - 2016 Regulation of the gene expression of the type IX secretion component proteins in Porphyromonas gingivalis
- 2012 - 2014 Challenge to generate site-direct mutants of the periodontal pathogen Prevotella intermedia
- 2010 - 2011 Dual regulation of secretion system of periodontal virulence factors by novel two-component system and ECF sigma factor
- 2008 - 2010 Secretion mechanism of pathogenic proteases and adhesions in the periodontal pathogen Porphyromonas gingivalis.
- 2006 - 2007 ゲノム情報に基づいたP.gingivalisの宿主内での病原性因子調節機構の解析
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Papers (77)：
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Yuko Sasaki, Mikio Shoji, Takayuki Sueyoshi, Satoshi Shibata, Takehiro Matsuo, Hideharu Yukitake, Matthias Wolf, Mariko Naito. A conditional gene expression system in Porphyromonas gingivalis for study of the secretion mechanisms of lipoproteins and T9SS cargo proteins. Molecular Oral Microbiology. 2023
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M. Shoji, K. Sato, H. Yukitake, A. Kamaguchi, Y. Sasaki, M. Naito, K. Nakayama. Identification of genes encoding glycosyltransferases involved in lipopolysaccharide synthesis in Porphyromonas gingivalis. Molecular Oral Microbiology. 2021. 33. 1. 68-80
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Hideharu Yukitake, Mikio Shoji, Keiko Sato, Yusuke Handa, Mariko Naito, Katsumi Imada, Koji Nakayama. PorA, a conserved C-terminal domain-containing protein, impacts the PorXY-SigP signaling of the type IX secretion system. Scientific Reports. 2020. 10. 1
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Sato K, Kakuda S, Yukitake H, Kondo Y, Shoji M, Takebe K, Narita Y, Naito M, Nakane D, Abiko Y, et al. Immunoglobulin-like domains of the cargo proteins are essential for protein stability during secretion by the type IX secretion system. Molecular microbiology. 2018
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Shoji M, Sato K, Yukitake H, Kamaguchi A, Sasaki Y, Naito M, Nakayama K. Identification of genes encoding glycosyltransferases involved in lipopolysaccharide synthesis in Porphyromonas gingivalis. Mol Oral Microbiol. 2018. 33. 1. 68-80
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MISC (49)：
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Poster. Nippon Saikingaku Zasshi. 2023. 78. 1. 80-80
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Mikio Shoji, Keiko Sato, Hideharu Yukitake, Yoshio Kondo, Yuka Narita, Tomoko Kadowaki, Mariko Naito, Koji Nakayama. Por Secretion System-Dependent Secretion and Glycosylation of Porphyromonas gingivalis Hemin-Binding Protein 35 (vol 6, e21372, 2011). PLOS ONE. 2018. 13. 8
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Mikio Shoji, Keiko Sato, Hideharu Yukitake, Yoshio Kondo, Yuka Narita, Tomoko Kadowaki, Mariko Naito, Koji Nakayama. Correction: Por secretion system-dependent secretion and glycosylation of porphyromonas gingivalis hemin-binding protein 35 (PLoS ONE 6 (2011) 6 (e21372) DOI: 10.1371/journal.pone.0021372). PLoS ONE. 2018. 13
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雪竹英治, 門脇知子, 内藤真理子, 佐藤啓子, 庄子幹郎, 中山浩次. Porphyromonas gingivalis IX型分泌機構の調節メカニズムに関与する分子の解析. 日本細菌学雑誌(Web). 2017. 72. 1
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田口裕子, 佐藤啓子, 雪竹英治, 井上哲圭, 井上哲圭, 中山真彰, 中山真彰, 内藤真理子, 中山浩次, 大原直也, et al. Porphyromonas gingivalisの表層蛋白質の修飾と機能に関与する分子の解析. 日本細菌学雑誌. 2015. 70. 1
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Lectures and oral presentations (17)：
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T9SS CTD タンパク質の一つであるPorAはT9SS構成タンパク質の遺伝子発現調節に関わる
(第94回日本細菌学会総会 2021)
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A cargo protein, PorA, of the type IX secretion system (T9SS) acts as a T9SS regulator upstream of the two-component system PorXY and the ECF sigma factor SigP
(2019)
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9型分泌機構の基質タンパク質であるPorAは二成分制御系PorXYとECFシグマ因子SigPの上流で正の制御因子として機能する
(第72回日本細菌学会九州支部総会 2019)
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A T9SS cargo protein involved in regulation of the T9SS expression in Porphyromonas gingivalis
(2018)
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Porphyromonas gingivalis IX型分泌機構の調節メカニズムに関与する分子の解析
(第90回日本細菌学会総会 2017)
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Professional career (1)：
Work history (2)：
- 2006 - - 長崎大学大学院医歯薬学総合研究科新興感染症病態制御学系専攻新興感染症病態制御学系専攻(歯) 職員(技術系)
- 2006 - - Engineering Staff,Infection Research,Infection Research,Graduate School of Biomedical Sciences,Nagasaki University
Association Membership(s) (4)：
歯科基礎医学会
, 日本細菌学会
, JAPANESE ASSOCIATION FOR ORAL BIOLOGY
, JAPANESE SOCIETY FOR BACTERIOLOGY
