Rchr
J-GLOBAL ID:200901014702626829   Update date: Feb. 01, 2024

Mori Hiroyuki

モリ ヒロユキ | Mori Hiroyuki
Affiliation and department:
Homepage URL  (1): https://infront-biomembrane.jp
Research field  (3): Molecular biology ,  Functional biochemistry ,  Cell biology
Research keywords  (2): 生体膜 ,  Biomembrane
Research theme for competitive and other funds  (36):
  • 2023 - 2026 タンパク質膜透過装置による分泌モニター因子VemPの翻訳アレスト解除の調節メカニズム
  • 2022 - 2026 大腸菌BepAによる外膜タンパク質トリアージ機構とその制御
  • 2020 - 2023 分泌モニタータンパク質VemPの翻訳アレスト解除の分子機構
  • 2017 - 2020 Molecular mechanism of protein translocation stimulation by SecDF using proton motive force
  • 2017 - 2019 新生鎖VemPの翻訳伸長停止/解除機構の解明
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Papers (81):
  • 石井 英治, 松田 重輝, 飯田 哲也, 秋山 芳展, 森 博幸. 細菌の遺伝子発現制御の新展開 ビブリオ属細菌における翻訳アレストを介した遺伝子発現制御. 日本細菌学雑誌. 2023. 78. 1. 32-32
  • Ryoji Miyazaki, Mengting Ai, Natsuko Tanaka, Takehiro Suzuki, Naoshi Dhomae, Tomoya Tsukazaki, Yoshinori Akiyama, Hiroyuki Mori. Inner membrane YfgM-PpiD heterodimer acts as a functional unit that associates with the SecY/E/G translocon and promotes protein translocation. The Journal of biological chemistry. 2022. 298. 11. 102572-102572
  • Ryoji Miyazaki, Hiroyuki Mori, Yoshinori Akiyama. A Photo-Crosslinking Approach to Monitoring the Assembly of an LptD Intermediate with LptE in a Living Cell. Methods in molecular biology (Clifton, N.J.). 2022. 2548. 97-107
  • MIYAZAKI Ryoji, MORI Hiroyuki, AKIYAMA Yoshinori. PiXie Analysis for Monitoring Dynamic Protein Interaction and Folding in a Living Cell. Seibutsu Butsuri. 2021. 61. 1. 36-39
  • Ryoji Miyazaki, Yoshinori Akiyama, Hiroyuki Mori. Fine interaction profiling of VemP and mechanisms responsible for its translocation-coupled arrest-cancelation. eLife. 2020. 9
more...
MISC (83):
Books (5):
  • 「タンパク質膜透過の駆動メカニズム」分子マシンの科学
    化学同人 2017
  • 「ビブリオ属細菌における2つのタンパク質膜透過促進因子の生理的意義と使い分け機構」医学の歩み
    医歯薬出版 2017
  • 細菌のタンパク質分泌を促進する 膜タンパク質 SecDF の構造と機能
    日本農芸化学会「化学と生物」 2013
  • 「立体構造解析からみえてきたSecA による蛋白質膜透過の分子メカニズム」蛋白質核酸酵素54, 685-695
    共立出版 2009
  • The Sec protein secretion system
    Caister Academic Press, Norfolk, UK. 2009
Lectures and oral presentations  (29):
  • Nascent chain-monitored remodeling of the Sec machinery for salinity adaptation of a marine bacterium, Vibrio alginolyticus.
    (Commemorative symposium for 33rd international prize for biology ‘Marine biology opens a frontier for the future’ 2017)
  • Identification and characterization of a translation arrest motif in VemP by systematic mutational analysis.
    (2017)
  • Structure and Physiological Function of SecDF That Enhances Protein Export.
    (International symposium ‘Harmonized supermolecular motility machinery and its diversity’ 2017)
  • Nascent chain-monitored remodeling of the Sec machinery for salinity adaptation of marine bacteria.
    (NASCENT CHAIN BIOLOGY 2016)
  • Environmental adaptation of marine Vibrio by nascent chain-mediated remodeling of protein export machinery.
    (2016)
more...
Education (3):
  • 1990 - 1992 Osaka University
  • 1988 - 1990 Osaka University
  • 1984 - 1988 Osaka University School of Science
Professional career (1):
  • Doctor of Science (Osaka University)
Work history (7):
  • 2022/04 - 現在 Kyoto University
  • 2016/10 - 2022/03 Kyoto University
  • 2007/08 - 2016/09 Kyoto University Institute for Virus Research
  • 2007/04 - 2007/07 Kyoto University Institute for Virus Research
  • 1996/10 - 2007/03 Kyoto University Institute for Virus Research
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Association Membership(s) (2):
日本分子生物学会 ,  日本生化学会
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