Rchr
J-GLOBAL ID：200901015936458349
Update date: Mar. 30, 2024
Murata Mariko
ムラタ マリコ | Murata Mariko
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
http://www.medic.mie-u.ac.jp/organization/course/eiseigaku/
Research field (3)：
Healthcare management, medical sociology
, Hygiene and public health (non-laboratory)
, Hygiene and public health (laboratory)
Research keywords (4)：
公衆衛生学・健康科学
, 衛生学
, Public health・Health science
, Hygiene
Research theme for competitive and other funds (54)：
- 2021 - 2024 果糖は発がんおよびその進展にどう作用するのか?
- 2019 - 2023 認知症における血中エクソソーム内包酸化損傷タンパク質の変動解析とリスク診断
- 2019 - 2023 Mechanism of epigenetic aberration in inflammation-related carcinogenesis: molecular epidemiology by a comparison of risk factors between Japan and China
- 2019 - 2022 Roles of DAMP and autophagy in inflammation-related carcinogenesis and its application to cancer prevention
- 2019 - 2022 An Empirical Study on the Effect of Improvement of Operating Room Noise Environment on Health and Cognitive Behavioral Function of Medical Workers
- 2019 - 2021 Can a dietary factor taurine suppress carcinogenesis?
- 2018 - 2021 Clarification of the role of DAMP in health effects caused by particulate matters and risk assessment
- 2017 - 2020 A comparative molecular epidemiology study of carcinogenicity on the liver flube infection in the Xijiang (China) and Mekong river (Thailand)
- 2016 - 2020 途上国におけるアルツハイマー病発症リスクの検証: 食と環境との関わり
- 2016 - 2019 Carcinogenic mechanisms of stem cells in inflammation-related cancer and its prevention
- 2016 - 2019 Establishment of early diagnostic markers for nasopharyngeal carcinoma and experimental verification through fieldwork in southern China
- 2015 - 2018 Development of minimal-invasive and quantitative analytical method for nitrated DNA damage, and its application to risk assessment of inflammation-related carcinogenesis
- 2015 - 2017 Reset of the epigenetic abnormality by dietary factors for cancer prevention
- 2014 - 2017 Proteomic profiling of exosomal proteins for the early diagnosis of Alzheimer's disease and prevention of Alzheimer's disease
- 2013 - 2016 Epigenetic alteration in inflammation-related carcinogenesis and its application to cancer prevention and therapy
- 2013 - 2016 Development of screening methods for early detection of nasopharyngeal carcinoma in southern China
- 2013 - 2015 炎症関連発がんにおけるエピゲノム異常の機構解明とがん予防・治療への応用
- 2011 - 2014 Development of risk assessment methods for parkinson's disease using carbonylated protein, a protein oxidation product, as a predictive indicator
- 2011 - 2013 Evaluation and prevention of Alzheimer's disease associated with lifestyle and dietary habit factors in the developing country.
- 2011 - 2012 Roles of microRNA in inflammation-related carcinogenesis and its possibility for use as a biomarker
- 2010 - 2012 Molecular mechanism of infection/inflammation-associatedcarcinogenesis and cancer prevention
- 2010 - 2012 A molecular epidemiological study to explore arsenic relation carcinogenesis and malignant progression in an arsenic endemic rural region in Shanxi province of China
- 2010 - 2012 Molecular epidemiology of nasopharyngeal carcinoma in southern Chinaand searching for early detection biomarkers
- 2009 - 2011 Risk assessment of carcinogenicity and fibrogenicity in respiratory systems induced by fibrous and particulate materials
- 2009 - 2011 Molecular epidemiological study on cholangio-carcinogenesis induced by liver fluke Opisthorchis viverrini in Thailand.
- 2008 - 2010 Mechanism of neuronal death induced by oxidative stress in Parkinson's disease
- 2007 - 2009 Roles of obesity and dietary factors on multistage carcinogenesis and risk assessment
- 2007 - 2009 Molecular epidemiology study on carcinogenic mechanism of Epstein-Barr-associated nasopharyngeal carcinoma and modification by environmental factors in southern China
- 2007 - 2008 感染症・炎症に起因する発がんの新規バイオマーカーの開発とがん予防
- 2006 - 2008 Development of the biomarker analysis system for evaluating the risk of carcinogenesis related to infection and inflammation
- 2006 - 2008 Molecular epidemiological study for bladder carcinogenesis induced by parasite in Egypt
- 2005 - 2008 Research of Incidence and Risk Factor of Alzheimer's Disease and Life-Style Related Disease
- 2005 - 2007 Functional proteomic analysis of oxidatively modified proteins associated with senescence acceleration and prevention of pathological aging
- 2005 - 2006 Mechanism of carcinogenesis in female reproductive organs induced by environmental estrogens
- 2005 - 2006 Evaluation of the efficacy and safety of antioxidant supplements on the basis of oxidative DNA damage profiles
- 2003 - 2005 The mechanism for the formation of hotspots in relation to evaluation of carcinogenic risks of environmental chemicals
- 2003 - 2005 Molecular epidemiological study on the pathogenesis of cholangiocarcinoma caused by infection with liver flukes in Thailand
- 2002 - 2003 環境化学物質の内分泌撹乱作用と遺伝毒性の発現機構
- 2001 - 2003 Development of evaluation system for cancer chemopreventive agents based on DNA damage inhibition and gene expression
- 2000 - 2002 Analysis of sequence-specific DNA damage by oxidative stress and prevention of cancer and aging
- 2001 - 2001 環境化学物質の内分泌撹乱作用と遺伝毒性の発現機構
- 2000 - 2001 Analysis of the human DNA damage by dietary factors via reactive oxygen species and cancer prevention
- 1999 - 2001 Evaluation of toxicity of environmental chemicals on the basis of their estrogenic activity and DNA-damaging ability and regional risk assessment
- 1998 - 2000 The method of safety evaluation of chemopreventive agents based on the ability of damaging human genes
- 1997 - 1999 Mechanisms of DNA damage induced by environmental factors and cancer chemoprevention
- 1998 - 1998 太陽紫外線特にUVAによる遺伝子損傷機構の解析
- 1997 - 1998 Analysis of the human DNA damageby antioxidants for evaluation of safety in cancer chemoprevention
- 1997 - 1997 NOと活性酸素の発がんにおける役割
- 1994 - 1996 Clinical study of postnatal depression. -The impact on child development-
- 1988 - 1990 Studies on the Effects of Infrasound on Vestibular Function.
- 1985 - 1986 Studies on the successive effects of noise exposure to pregnant mice
- Mechanisms of carcinogenesis induced by environmental factors
- Study on mental health for mother and child
- Study on teratogenic effects of noise
Show all
Papers (179)：
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Kaoru Midorikawa, Kokoro Kobayashi, Shinya Kato, Shosuke Kawanishi, Hatasu Kobayashi, Shinji Oikawa, Mariko Murata. Oxidative DNA damage: induction by fructose, in vitro, and its enhancement by hydrogen peroxide. Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 2023. 893. 503719-503719
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Yuichiro Hirao, Hatasu Kobayashi, Yurie Mori, Shinya Kato, Shosuke Kawanishi, Mariko Murata, Shinji Oikawa. Myricetin causes site-specific DNA damage via reactive oxygen species generation by redox interactions with copper ions. Mutation research. Genetic toxicology and environmental mutagenesis. 2023. 891. 503694-503694
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Guofei Feng, Yasushi Arima, Kaoru Midorikawa, Hatasu Kobayashi, Shinji Oikawa, Weilin Zhao, Zhe Zhang, Kazuhiko Takeuchi, Mariko Murata. Knockdown of TFRC suppressed the progression of nasopharyngeal carcinoma by downregulating the PI3K/Akt/mTOR pathway. Cancer Cell International. 2023. 23. 1. 185
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Hajime Ishinaga, Yoshinaga Okugawa, Bo Hou, Feng He, Chengzeng Yin, Mariko Murata, Yuji Toiyama, Kazuhiko Takeuchi. The role of miR-21 as a predictive biomarker and a potential target to improve the effects of chemoradiotherapy against head and neck squamous cell carcinoma. Journal of Radiation Research. 2023. 64. 4. 668-676
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Waleeporn Kaewlert, Chadamas Sakonsinsiri, Worachart Lert-itthiporn, Piti Ungarreevittaya, Chawalit Pairojkul, Somchai Pinlaor, Mariko Murata, Raynoo Thanan. Overexpression of Insulin Receptor Substrate 1 (IRS1) Relates to Poor Prognosis and Promotes Proliferation, Stemness, Migration, and Oxidative Stress Resistance in Cholangiocarcinoma. International Journal of Molecular Sciences. 2023. 24. 3. 2428-2428
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MISC (224)：
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馮 国飛, 有馬 寧, 翠川 薫, 及川 伸二, 小林 果, Zhao Weilin, Zhang Zhe, 竹内 万彦, 村田 真理子. トランスフェリン受容体のノックダウンは上咽頭癌の細胞増殖および浸潤を抑制する(Knockdown of transferrin receptor suppresses cell proliferation and invasion of nasopharyngeal carcinoma). 日本癌学会総会記事. 2022. 81回. P-1290
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Effect of RNF213 suppression on endoplasmic reticulum stress. 2022. 77. Suppl. S184-S184
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王 桂鳳, 平本 恵一, 有馬 寧, 大西 志保, 村田 真理子, 川西 正祐. グリチルリチンによる発がん抑制に伴うマウス脾臓の免疫細胞への影響. 日本衛生学雑誌. 2022. 77. Suppl. S219-S219
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岡野 元彦, 何 峰, 有馬 寧, 小林 果, 及川 伸二, 西村 廣明, 俵 功, 村田 真理子. 上咽頭癌細胞のオートファジー及びアポトーシス関連分子発現に対するタウリンの影響. 日本衛生学雑誌. 2022. 77. Suppl. S220-S220
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Feng Guofei, He Feng, 有馬 寧, 翠川 薫, 及川 伸二, 小林 果, 竹内 万彦, 村田 真理子. GDF10はTGF-β/Smad/NF-κB経路を介して上咽頭癌の進展を抑制する. 日本衛生学雑誌. 2022. 77. Suppl. S222-S222
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Books (8)：
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腫瘍薬学
南山堂 2010
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子どもの保健-理論と実践-
日本小児医事出版社 2010
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食品機能性の科学
食品機能性の科学編集委員会 2008
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環境エストロゲンによる生殖器系発がんの機構解明とリスク評価
[村田真理子] 2007
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食餌性因子による活性酸素を介するヒト遺伝子損傷の解析とがん予防
[村田真理子] 2002
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Lectures and oral presentations (84)：
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アクリルアミド代謝産物による塩基配列特異的DNA損傷機構
(第91回日本衛生学会学術総会 2021)
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甘草の主成分グリチルリチンはAOM+DSS誘導性大腸がんを抑制する
(第91回日本衛生学会学術総会 2021)
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Knockdown of transferrin receptor 1 inhibits cell proliferation in nasopharyngeal carcinoma
(2021)
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Downregulation of GLUT5 suppresses cell proliferation and migration in cholangiocarcinoma cells
(2021)
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Rnf213抑制はオスAkitaマウスと異なりメスAkitaマウスの糖尿病を改善しない
(第91回日本衛生学会学術総会 2021)
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Education (1)：
- - 1984 Mie University Faculty of Medicine
Professional career (1)：
Work history (1)：
- 2006/12 - 現在 Mie University Graduate School of Medicine Department of Environmental and Molecular Medicine Professor
Awards (2)：
- 2021/03 - 日本衛生学会 Environmental Health and Preventive Medicine(国際誌)Editor-in-chief Award
- 2018/03 - The Japanese Society for Hygiene -
Association Membership(s) (6)：
日本癌学会
, 日本健康教育学会
, 生理人類学会
, 日本産業衛生学会
, 日本公衆衛生学会
, 日本衛生学会
