Morioka Yuka

モリオカユカ | Morioka Yuka

Affiliation and department：
Job title： Associate professor

Research field (1)： Laboratory animal science

Research keywords (4)：遺伝子工学 , 発生工学 , 遺伝子改変動物 , ウイルスベクター

Research theme for competitive and other funds (21)：

2023 - 2025 ロイシンセンシングによる腫瘍発生機序の解明と予防法の開発
2020 - 2023 母児間鉄代謝に関わる新規因子の解明
2017 - 2020 Analysis of PKX-deficient mice that indicate placental disorder.
2016 - 2019 Molecular targets to suppress microenvironment changes and invasive cancer recurrence after radiotherapy
2015 - 2017 Analysis of a novel protein kinase-deficient mice that indicate perinatal disorders.

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Papers (35)：

Jun-Ichi Kashiwakura, Kodai Saitoh, Takeru Ihara, Yuto Sasaki, Kota Kagohashi, Shiyo Enohara, Yuka Morioka, Hiroshi Watarai, Ryuta Muromoto, Yuichi Kitai, et al. Correction: Expression of signal-transducing adaptor protein-1 attenuates experimental autoimmune hepatitis via down-regulating activation and homeostasis of invariant natural killer T cells. PloS one. 2021. 16. 4. e0250536
Jun-ichi Kashiwakura, Kodai Saitoh, Takeru Ihara, Yuto Sasaki, Kota Kagohashi, Shiyo Enohara, Yuka Morioka, Hiroshi Watarai, Ryuta Muromoto, Yuichi Kitai, et al. Expression of signal-transducing adaptor protein-1 attenuates experimental autoimmune hepatitis via down-regulating activation and homeostasis of invariant natural killer T cells. PLOS ONE. 2020. 15. 11. e0241440-e0241440
Hirotaka Watanabe, Kojiro Ishibashi, Hiroki Mano, Sho Kitamoto, Nanami Sato, Kazuya Hoshiba, Mugihiko Kato, Fumihiko Matsuzawa, Yasuto Takeuchi, Takanobu Shirai, et al. Mutant p53-Expressing Cells Undergo Necroptosis via Cell Competition with the Neighboring Normal Epithelial Cells. Cell reports. 2018. 23. 13. 3721-3729
Yuka Morioka, Jin-Min Nam, Takashi Ohashi. Nik-related kinase regulates trophoblast proliferation and placental development by modulating AKT phosphorylation. PLOS ONE. 2017. 12. 2. e0171503
Megumi Tatematsu, Ryuji Yoshida, Yuka Morioka, Noriko Ishii, Kenji Funami, Ayako Watanabe, Kazuko Saeki, Tsukasa Seya, Misako Matsumoto. Raftlin Controls Lipopolysaccharide-Induced TLR4 Internalization and TICAM-1 Signaling in a Cell Type-Specific Manner. JOURNAL OF IMMUNOLOGY. 2016. 196. 9. 3865-3876

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MISC (4)：

Yusuke Eto, Shinnosuke Kurachi, Tomohiro Morishige, Xinglei Yao, Hikaru Watanabe, Yuka Okada, Hiroyuki Mizuguchi, Yasuo Tsutsumi, Naoki Okada, Shinsaku Nakagawa. Transductional and transcriptional tumor-targeting using adenoviral vector with PEGylation and TERT promoter on systemic administration into tumor-bearing mice. CANCER RESEARCH. 2006. 66. 8
Yuka Okada, Naoki Okada, Shinsaku Nakagawa, Hiroyuki Mizuguchi, Makiko Kanehira, Naoko Nishino, Koichi Takahashi, Nobuyasu Mizuno, Takao Hayakawa, Tadanori Mayumi. Erratum: Fiber-mutant technique can augment gene transduction efficacy and anti-tumor effects against established murine melanoma by cytokine-gene therapy using adenovirus vectors (Cancer Letters (2002) 177 (57-63)). Cancer Letters. 2004. 204. 115-116
Y Okada, N Okada, H Mizuguchi, K Takahashi, T Hayakawa, T Mayumi, N Mizuno. Optimization of antitumor efficacy and safety of in vivo cytokine gene therapy using RGD fiber-mutant adenovirus vector for preexisting murine melanoma. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. 2004. 1670. 3. 172-180
中川哲彦, 水口裕之, 今津進, 森岡裕香, 中川晋作, 真弓忠範, 中西真人. New strategy for solid cancer gene therapy. Induction of anti-tumor effect by TNF-.ALPHA. gene transfer into tumor control artery. 日本薬学会年会要旨集. 1996. 116th. Pt 4. 78

Education (1)：

- 1996 Osaka University School of Pharmaceutical Sciences

Professional career (1)：

博士(薬学) (大阪大学)

Work history (10)：

2019/05 - 現在 Kobe University Institute for Experimental Animals, Graduate School of Medicine
2017/04 - 2019/04 Hokkaido University Institute for Genetic Medicine
2012/04 - 2017/03 Hokkaido University Institute for Genetic Medicine
2010/02 - 2012/03 Hokkaido University Institute for Genetic Medicine
2009/04 - 2010/01 Osaka University Research Institute for Microbial Diseases

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Awards (3)：

2007 - 財団法人阪大微生物病研究会優秀研究奨励賞
2007 - 日本薬学会近畿支部奨励賞
2006 - 日本生殖免疫学会学会賞

Association Membership(s) (4)：

JAPANESE ASSOCIATION FOR LABORATORY ANIMAL SCIENCE , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , 日本生殖免疫学会 , 日本癌学会

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