Rchr
J-GLOBAL ID:200901016370744914   Update date: Feb. 01, 2024

MOTOKO SASAKI

ササキ モトコ | MOTOKO SASAKI
Affiliation and department:
Job title: Associate Professor
Research field  (1): Human pathology
Research keywords  (1): Pathology of the hepatobiliary diseases; primary biliary cholangitis (cirrhosis), Cholangiocarcinoma
Research theme for competitive and other funds  (20):
  • 2022 - 2025 老化細胞を標的とした原発性胆汁性胆管炎の新しい治療法開発
  • 2018 - 2021 Development of new therapy for liver disease by regulating cellular senescence
  • 2015 - 2018 Involvement of dysregulated autophagy in autoimmune diseases
  • 2012 - 2015 Novel approach to primary biliary cirrhosis putting focus on deregulated autophagy
  • 2009 - 2011 Novel approach to liver disease from aspect of cellular senescence
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Papers (367):
  • Motoko Sasaki, Yasunori Sato, Yasuni Nakanuma. Nestin may be a candidate marker for differential diagnosis between small duct type and large duct type intrahepatic cholangiocarcinomas. Pathology - Research and Practice. 2024. 253. 155061-155061
  • Soo Ryang Kim, Soo Ki Kim, Yu-Ichiro Koma, Motoko Sasaki, Akira Asai, Hiroki Nishikawa. Hepatic Inflammatory Pseudotumor-Focusing on Its Heterogeneity. Diagnostics (Basel, Switzerland). 2023. 13. 17
  • Motoko Sasaki, Yasunori Sato, Yasuni Nakanuma. Bile duct adenoma and small-sized small duct type intrahepatic cholangiocarcinoma show distinct differences in genetic alterations, expression of IMP3 and EZH2 and stromal and inflammatory components. Histopathology. 2023. 83. 2. 298-309
  • Motoko Sasaki, Yasunori Sato, Yasuni Nakanuma. An involvement of Hippo-yes-associated protein pathway in biliary epithelial senescence in primary biliary cholangitis. Clinics and research in hepatology and gastroenterology. 2023. 47. 4. 102106-102106
  • Soo Ryang Kim, Soo Ki Kim, Takako Fujii, Hisato Kobayashi, Toyokazu Okuda, Takanobu Hayakumo, Atsushi Nakai, Yumi Fujii, Ryuji Suzuki, Noriko Sasase, et al. Drug-induced sarcoidosis-like reaction three months after BNT162b2 mRNA COVID-19 vaccination: A case report and review of literature. World journal of clinical cases. 2023. 11. 1. 177-186
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MISC (149):
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Books (22):
  • 胆道疾患を診る医師のための胆道病理テキスト
    南江堂, 東京 2015
  • 胆道疾患を診る医師のための胆道病理テキスト
    南江堂, 東京 2015
  • 胆道疾患を診る医師のための胆道病理テキスト
    南江堂, 東京 2015
  • C型肝炎の診療を極める。〜基本から最前線まで〜
    文光堂, 東京 2014
  • 専門医のための消化器病学 第2版
    2013
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Lectures and oral presentations  (48):
  • Enhanced VASH1 expression in splenic sinus lining cells relates to splenomegaly in IPH
    (The Asian Pacific Association for the Study of the Liver (APASL) 2016 Tokyo 2016)
  • Bile acids and cholangiocyte autophagy
    (The XXIV International Bile Acid Meeting“Bile Acids in Health and Disease”. Düsseldorf 2016)
  • ARID 1A mutations may represent a novel pathway of carcinogenesis in biliary carcinomas.
    (The 66th Annual meeting of American Association for the Study of Liver Diseases (AASLD). San Francisco 2015)
  • Increased expression of ORM1-like protein 3 (ORMDL3) in biliary epithelial cells may be related to the pathogenesis of primary biliary cirrhosis.
    (The 66th Annual meeting of American Association for the Study of Liver Diseases (AASLD). San Francisco 2015)
  • Recent Advances in Liver Pathology. Cholangiocarcinoma and precursor lesions: An involvement of cellular senescence in cholangiocarcinogenesis.
    (The Annual Meeting of GEST 2015)
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Education (2):
  • 1989 - Kanazawa University Graduate School, Division of Medicine
  • - 1988 Kanazawa University
Professional career (1):
  • 医学博士
Committee career (10):
  • 2016/04 - 現在 日本肝臓学会 評議員
  • 2014/04 - 現在 日本臨床細胞学会 評議員
  • 2014/04 - 現在 日本胆道学会 評議員
  • 2013/04 - 現在 日本肝癌研究会 幹事
  • 2011/04 - 現在 日本肝胆膵外科学会 胆道癌取扱い規約委員会実務委員
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Awards (6):
  • 2017/12 - はあざみ女性研究者賞 (紫花賞)
  • 2017/09 - 北國がん基金「北國がん基金研究助成」
  • 金沢市医師会 金沢医学館記念医学賞 (2009)
  • 日本病理学会学術研究賞 (2009)
  • 北國がん基金 北國がん基金研究助成 (2006)
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Association Membership(s) (8):
American Association for the study of liver diseases(AASLD) ,  日本組織細胞化学会 ,  International Academy of Pathology (IAP) ,  日本臨床細胞学会 ,  日本肝癌研究会 ,  日本胆道学会 ,  日本肝臓学会 ,  日本病理学会
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