Yamazaki Naoshi

ヤマザキナオシ | Yamazaki Naoshi

Affiliation and department：
Other affiliations (2)：

徳島大学薬学部准教授
徳島大学大学院薬科学教育部准教授

Research field (3)： Pharmaceuticals - health and biochemistry , Cell biology , Molecular biology

Research keywords (2)：生物系薬学 , Biopharmaceutics

Research theme for competitive and other funds (14)：

2016 - 2019 Use of modified U1 snRNA for rescue from exon skipping caused by 5' splice site mutation of human CTSA gene
2011 - 2012 Development of a novel approach toward nucleic acids-based therapeutics
2010 - 2012 Characterization of a novel protein which inhibits adipocytes differentiation
2008 - 2009 腫瘍内微小環境変化を利用した新規DDSの開発
2004 - 2005 脂肪細胞の分化を抑制する新規タンパク質の解析とこれを標的とした抗肥満戦略

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Papers (66)：

Kiri Akieda, Kazuto Takegawa, Takeshi Ito, Gaku Nagayama, Naoshi Yamazaki, Yuka Nagasaki, Kohei Nishino, Hidetaka Kosako, Yasuo Shinohara. Unique Behavior of Bacterially Expressed Rat Carnitine Palmitoyltransferase 2 and Its Catalytic Activity. Biological and Pharmaceutical Bulletin. 2024. 47. 1. 23-27
Toshihiko Tsutsumi, Kohei Kawabata, Naoshi Yamazaki, Kenji Tsukigawa, Hiroyuki Nishi, Akira Tokumura. Extracellular and intracellular productions of lysophosphatidic acids and cyclic phosphatidic acids by lysophospholipase D from exogenously added lysophosphatidylcholines to cultured NRK52E cells. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2023. 1868. 9. 159349-159349
Kazuto Takegawa, Takeshi Ito, Atsushi Yamamoto, Naoshi Yamazaki, Mitsuru Shindo, Yasuo Shinohara. KH-17, a simplified derivative of bongkrekic acid, weakly inhibits the mitochondrial ADP/ATP carrier from both sides of the inner mitochondrial membrane. Chemical Biology & Drug Design. 2023. 101. 4. 865-872
Yoshinobu Fujiwara, Takeshi Ito, Atsumi Toiyama, Takenori Yamamoto, Naoshi Yamazaki, Mitsuru Shindo, Yasuo Shinohara. Suramin Inhibits Mitochondrial ADP/ATP Carrier, Not Only from the Cytosolic Side But Also from the Matrix Side, of the Mitochondrial Inner Membrane. BPB Reports. 2021. 4. 3. 92-97
Toshihiko Tsutsumi, Risa Matsuda, Katsuya Morito, Kohei Kawabata, Miho Yokota, Miki Nikawadori, Manami Inoue-Fujiwara, Satoshi Kawashima, Mayumi Hidaka, Takenori Yamamoto, et al. Identification of human glycerophosphodiesterase 3 as an ecto phospholipase C that converts the G protein-coupled receptor 55 agonist lysophosphatidylinositol to bioactive monoacylglycerols in cultured mammalian cells. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2020. 1865. 9. 158761-158761

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MISC (4)：

木村麻里安, 金澤慶祐, 斎藤朱里, 山崎尚志, 池啓伸, 伊藤孝司, 南川典昭, 滝口祥令. 改変U1 snRNAを用いた変異カテプシンAスプライス異常の修復. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [1P0762]-[1P0762]
池啓伸, 山崎尚志, 田中翔子, 金澤慶祐, 滝口祥令, 南川典昭, 伊藤孝司. 改変U1 snRNAによるヒトカテプシンAの遺伝子発現におけるスプライシング異常の修復. 日本生化学会大会プログラム・講演要旨集. 2014. 87回. [3P-362]
大黒多希子, 篠原康雄, 島厚志, 山崎尚志, 寺田弘. 褐色脂肪組織と白色脂肪組織におけるエネルギー代謝機構の相違. 日本分子生物学会年会プログラム・講演要旨集. 1996. 19. 263-263
ミトコンドリア輸送タンパクスーパーファミリー. 生体の科学. 1995. 46. 5.605

Patents (3)：

Lectures and oral presentations (16)：

GDE7はリゾホスホリパーゼD型酵素としてN-アシルエタノールアミンとLPAを生成する
(日本生化学会大会プログラム・講演要旨集 2016)
口腔粘膜上皮細胞に存在する膜結合型リゾホスホリパーゼD
(脂質生化学研究 2016)
改変U1 snRNAを用いたヒトカテプシンAの遺伝子発現におけるスプライシング異常の是正
(日本薬学会年会要旨集 2016)
Rescue of mutation-induced exon 7 skipping in human Cathepsin A by using modified U1 small nuclear RNA.
(MOLECULAR BIOLOGY OF THE CELL 2016)
改変型低分子RNAを用いたヒトカテプシンAの遺伝子発現におけるスプライシング異常の是正
(日本生化学会大会(Web) 2015)

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Professional career (1)：

ph.D.

Association Membership(s) (2)：

日本生化学会 , 日本薬学会

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