Rchr
J-GLOBAL ID：200901017851066630
Update date: Apr. 09, 2024
Kitamura Masahiro
キタムラ マサヒロ | Kitamura Masahiro
Affiliation and department：
Job title：
Associate Professor
Research field (1)：
Conservative dentistry and endodontics
Research keywords (4)：
歯周病の病態解析
, 歯周組織再生療法
, 歯周治療系歯学
, Periodontological Dentistry
Research theme for competitive and other funds (41)：
- 2021 - 2024 LAP依存性組織リモデリングによる歯周組織再生医療の新機軸
- 2019 - 2022 Activation of the regenerative process of periodontal tissue by elucidating the function of nerve-related molecules
- 2019 - 2021 Elucidation of mechanisms of regeneration of periodontal tissue by mathematical modelling
- 2019 - 2021 Fabrication of three-dimensional periodontal ligament tissue with nanometer-sized extracellular matrix films and creation of new system to analyze the cell-cell interaction
- 2018 - 2021 Challenge to the development of new treatments applying the enhancement of periodontal tissue regeneration by controlling stem cell aging
- 2016 - 2019 Application to periodontal tissue regeneration therapy by microcirculatory improvement medicine through non- neuronal cholinergic system
- 2015 - 2019 Identification of genetic risk factors of aggressive periodontitis by genome wide approach
- 2015 - 2018 A basic study for the development of stem cell-cytokine therapy aimed at the enhancing periodontal tissue regeneration effect.
- 2011 - 2015 Development of predictive periodontology based on molecular epidemiological study
- 2012 - 2014 Molecular pathogenesis of aggressive periodontitis utilizing hereditary connective tissue disorder mouse model
- 2011 - 2014 Molecular analysis of inflammasome in periodontal tissue destruction and regeneration.
- 2011 - 2014 A Challenge to the expansion of indications in periodontal tissue regeneration using FGF-2 by analyzing cross talk between signal molecules
- 2010 - 2013 FGF-2誘導性再生歯根膜における末梢神経ネットワーク再構築
- 2011 - 2012 Passive smoking-induced epigenetic regulation in tooth・periodontal tissue-associated genes.
- 2009 - 2011 脂肪組織由来の幹細胞とアディポカインによる炎症と再生の双方向性制御
- 2009 - 2011 Regulation of periodontal tissue re-generation with combination use of FGF-2 and on-demand 3D shaped graft material
- 2008 - 2009 遺伝子導入による歯周組織オルガノイドティシュエンジニアリング
- 2008 - 2009 Periodontal system biology: analysis of molecular bases of periodontal disease associated genes.
- 2007 - 2008 Involvement of purine nucleotide in periodontal regeneration by transplantation of adipose tissue-derived stem cells
- 2006 - 2008 The establishment of a new periodontal tissue regeneration therapyusing adipose-tissue derived stem cells
- 2006 - 2007 歯根膜全遺伝子パスウェイ解析による未来型オーダーメード歯周組織再生治療の新展開
- 2006 - 2007 New development of the regeneration ofpulp-dentin complex by FGF-2
- 2003 - 2005 Molecular-biological analysis by DNA microarray for diagnosis of occlusal trauma
- 2003 - 2004 ヒト歯根膜DNAチップを用いた根尖性歯周炎の遺伝子病態解析
- 2003 - 2004 Effects of basic fibroblast growth factor on the remodeling of alveolar bone
- 2002 - 2004 Establishment of periodontal tissue engineering by FGF-2
- 2001 - 2003 Study of preventive and early treatment for periodontitis and pulaiti s on person of advanced years
- 2001 - 2002 MULTIPLE ANALYSIS OF PERIODONTAL LESIONS BY DIFFERENTIAL DISPLAY
- 2002 - 咬合性外傷の診断法の開発
- 1998 - 2000 Establishment of periodontal regenerative therapy by basic libroblast growth lactor (bFGF)
- 1998 - 1999 The Role of Immune Regulatory Mechanisms in the Pathogenesis of Periapical Periodontitis
- 1997 - 1999 The development of controlled release-drug utilizing new quinolones for perlodontitis
- 1997 - 1999 Establishment of molecular biological diagnostic strategies for periodontal diseases
- 1998 - 1998 歯内ならびに歯周治療効果の細菌学的評価システムの構築とその疫学的調査への応用
- 1997 - 1998 歯周組織再生過程における細胞分化に関与する生理活性物質の検討
- 1996 - 1996 早期発症型歯周炎における局所病変の生化学的および分子生物学的検討
- 1995 - 1995 根尖性および辺縁性歯周炎におけるIL-1およびIL-1raの産生動態の検討
- 1995 - 歯周組織再生療法の開発
- 1992 - 1993 Diagnostic method of high risk patient for period on titis by martivariate statistical analysis
- 歯周病変の疾病活動度に関する研究
- Study on Periodontal Disease Activity
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Papers (93)：
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Koji Miki, Noboru Takeshita, Motozo Yamashita, Masahiro Kitamura, Shinya Murakami. Calcitonin gene-related peptide regulates periodontal tissue regeneration. Scientific reports. 2024. 14. 1. 1344-1344
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Shinji Matsuda, Tomoaki Shintani, Tsuyoshi Miyagawa, Hiromichi Yumoto, Yasutaka Komatsu, Nanae Dewake, Takanori Iwata, Takatoshi Nagano, Toshiya Morozumi, Ryoma Goto, et al. Effect of periodontal treatment on reducing chronic inflammation in systemically healthy patients with periodontal disease: a multicenter study. The American Journal of Medicine. 2023
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Masahide Takedachi, Kohsuke Kawasaki, Keigo Sawada, Kazuma Sakura, Mari Murata, Junpei Shimomura, Kazuma Kawakami, Chiaki Morimoto, Koji Miki, Noboru Takeshita, et al. Periodontal Tissue Regeneration by Transplantation of Autologous Adipose Tissue-Derived Multi-Lineage Progenitor Cells With Carbonate Apatite. Cell transplantation. 2023. 32. 9636897231198296-9636897231198296
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北垣 次郎太, 松本 昌大, 藤原 千春, 阪下 裕美, 平井 麻絵, 山下 元三, 北村 正博, 村上 伸也. 歯根膜細胞の骨芽細胞分化におけるカテプシンAの影響. 日本歯科保存学雑誌. 2023. 66. 4. 214-223
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Toshie Nagayasu-Tanaka, Jun Anzai, Masahide Takedachi, Masahiro Kitamura, Tatsuhiro Harada, Shinya Murakami. Effects of combined application of fibroblast growth factor (FGF)-2 and carbonate apatite for tissue regeneration in a beagle dog model of one-wall periodontal defect. Regenerative therapy. 2023. 23. 84-93
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MISC (187)：
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北村正博. 歯周組織再生剤」リグロス ®」誕生から6年ーそのアップデートとアップグレードー. 歯界展望. 2024. 143. 2. 228-243
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江口 千尋, 柏木 陽一郎, 北村 正博, 本多 二三枝, 池 美保, 村上 伸也. 非外科的歯周治療により垂直性骨吸収に改善がみられた一症例. 日本歯周病学会会誌. 2022. 64. 春季特別. 155-155
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Masahiro Kitamura, Motozo Yamashita. Regeneration Therapy for Periodontal Disease. Progress in Medicine. 2022. 42. 4. 75-80
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川嵜公輔, 竹立匡秀, 沢田啓吾, 下村純平, 村田真里, 河上和馬, 三木康史, 竹下登, 佐倉千萬, 松山晃文, et al. 炭酸アパタイトを足場材とした脂肪組織由来多系統前駆細胞の自己移植による歯周組織再生効果. 日本再生医療学会総会(Web). 2022. 21st
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北村 正博, 山下 元三, 三木 康史, 池上 久仁子, 竹立 匡秀, 柏木 陽一郎, 野崎 剛徳, 増田 聖, 石原 容子, 山中 克之, et al. 特定臨床研究 歯周炎を対象とした歯周組織再生剤(REGROTH)と人工骨(Cytrans Granules)の併用療法の安全性及び有効性の評価. 日本歯周病学会会誌. 2021. 63. 秋季特別. 122-122
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Books (21)：
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023 Regenerative Therapy Guidelines for Patients with Periodontal Disease
2023
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JSP Guidelines for the Use of Antimicrobial Agents in Patients with Periodontal Disease 2020
2020
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FGF-2と歯周組織再生療法
クインテッセンス出版 2020
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Exploring Innovative Frontiers in Periodontal Health and Implantology
2020
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HAND MANUAL of MAXILLOFACIAL SURGERY' 19
Quintessence 2019
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Works (6)：
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歯周炎を対象としたFGF-2のエムドゲイン®ゲルとの比較試験
北村 正博 2012 - 2014
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KCB-1D(FGF-2)歯周組織再生試験 (第III相・検証的試験)
北村 正博 2008 - 2010
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FGF-2観察研究(追跡調査)
北村 正博 2010 -
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辺縁性歯周炎患者を対象としたKCB-1D(塩基性線維芽細胞増殖因子)歯周組織再生試験(第II相) ープラセボを含む二重盲験・並行群間比較用量-反応試験ー
2005 -
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KCB-1D(塩基性線維芽細胞増殖因子)歯周組織再生試験(第II相) ー追跡調査ー
2004 -
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Education (4)：
- - 1990 Osaka University
- - 1990 Osaka University Graduate School, Division of Dental Research
- - 1986 Osaka University School of Dentistry School of Dentistry
- - 1986 Osaka University Faculty of Dentistry
Work history (6)：
- 2024/04 - 現在 Osaka University Graduate School of Dentistry
- 2008 - 2024/03 Osaka University Graduate School of Dentistry
- 1992 - 1996 Osaka University School of Dentistry
- 1992 - 1996 Osaka university faculty of Dentistry, Instructor
- 1996 - - 大阪大学歯学部附属病院 講師
- 1996 - - Osaka university dental hospital, Assistant professor
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Committee career (7)：
Awards (2)：
- 2011/12 - 2012 IADR/AADR William J. Gies Award for Clinical Research
- 2009/09 - R. EARL ROBINSON REGENERATION AWARD
Association Membership(s) (5)：
大阪大学歯学会
, THE JAPANESE SOCIETY OF INFLAMMATION AND REGENERATION
, THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE
, 日本歯科保存学会
, 日本歯周病学会
