Research keywords (2):
神経障害性疼痛 イオンチャンネル 電気生理
, Neuropathic pain Ion channels Electrophysiology
Research theme for competitive and other funds (11):
2019 - 2022 Establishment of the drug discovery research for pruritus treatments targeting neurotransmitter pathways
2015 - 2018 Synaptic mechanisms of pain relief by increasing inhibitory transmission in the spinal dorsal horn
2011 - 2013 Pathophysiological and pharmacological assessment of synaptic transmission in chronic pain states
2008 - 2010 Basic research for the establishment of the pharmacological assessment for drug development based on the study on synaptic transmission in chronic pain states
2008 - 2010 Spinal Cord Injury : Establishment of Measurement for Electrophysiological Function and Pharmacological Evaluation of Drugs
2006 - 2007 Modulation of synaptic transmission as the therapeutic strategies for chronic pain
2003 - 2004 The monoaminergic modulation of spinal motor function and the alteration in the motor disease
Takashi Iwai, Rei Mishima, Shigeto Hirayama, Honoka Nakajima, Misa Oyama, Shun Watanabe, Hideaki Fujii, Mitsuo Tanabe. SYK-623, a δ Opioid Receptor Inverse Agonist, Mitigates Chronic Stress-Induced Behavioral Abnormalities and Disrupted Neurogenesis. Journal of Clinical Medicine. 2024. 13. 2. 608-608
Motoki Morita, Shun Watanabe, Natsumi Nomura, Kanako Takano-Matsuzaki, Misa Oyama, Takashi Iwai, Mitsuo Tanabe. Sulfatide-selectin signaling in the spinal cord induces mechanical allodynia. Journal of neurochemistry. 2023. 164. 5. 658-670
Misa Oyama, Shun Watanabe, Takashi Iwai, Mitsuo Tanabe. Distinct synaptic mechanisms underlying the analgesic effects of γ-aminobutyric acid transporter subtypes 1 and 3 inhibitors in the spinal dorsal horn. Pain. 2022. 163. 2. 334-349
Misa Oyama, Shun Watanabe, Takashi Iwai, Mitsuo Tanabe. Mirogabalin activates the descending noradrenergic system by binding to the α2δ-1 subunit of voltage-gated Ca2+ channels to generate analgesic effects. Journal of Pharmacological Sciences. 2021. 146. 1. 33-39
宮田直樹, 田辺光男, 内田恵理子, 川崎ナナ. Stems used in drug names: For the better understanding of pharmacological actions of drugs New stems defining specific enzyme inhibitors-2: -parstat, -polstat, -telstat, -tristat, -xestat, etc. Pharm Tech Japan. 2021. 37. 1
宮田直樹, 田辺光男, 内田恵理子, 川崎ナナ. A common stem defining enzyme inhibitors: -stat(-). Pharm Tech Japan. 2021. 37. 5
宮田直樹, 頭金正博, 田辺光男, 内田恵理子, 川崎ナナ. Stems used in drug names: For the better understanding of pharmacological actions of drugs Special edition: Therapeutic agents for COVID-19. Pharm Tech Japan. 2021. 37. 8
宮田直樹, 田辺光男, 内田恵理子, 川崎ナナ. Stems used in drug names: For the better understanding of pharmacological actions of drugs Special edition: Therapeutic agents for COVID-19, Part 2. Pharm Tech Japan. 2021. 37. 9